iiinova — where your digital self keeps evolving

NTU Metabolism @ntumeta.bsky.social · 04/09/2026

🔬 The Matrix: Adipose Remodelled 📍 Nottingham | 7–8 Dec 2026 Meet experts in #AdiposeBiology and ECM research. Leading speakers, ECR career sessions + oral/poster prizes. Open to all-join us! ⏰ Super Early: 7 Sept ⏰ Abstracts/Early Booking: 7 Oct 👉 bit.ly/Matrix-2026 #NTU_SHIMR #NTU #ECRCommunity

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British Society for Neuroendocrinology @bsneuroendo.bsky.social · 26/08/2026

What is JNE's main strength? "Society-owned journals allow scientists to be in control of publishing research that serves science and society." #LoveMyJNE @rebeccadumbell.bsky.social chatted with JNE Editor-in-Chief @mikelehman.bsky.social to find out more:

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 28/07/2026

Never too old to be presenting a poster at conference! If you missed me at the poster session I'm still around for the rest of the meeting. Thank you @bsneuroendo.bsky.social for the travel grant to Nagoya for the #ICN2026! @infneuroendo.bsky.social @ntuneuro.bsky.social @ntumeta.bsky.social

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Nikoletta Kalenderoglou @nkalender.bsky.social · 19/05/2026

Increased #miR-10b-5p abundance promoted a #thermogenic program in #WhiteAdipose tissue, enhancing expression of thermogenic markers including #UCP1, #Cidea and #Ppargc1a, while improving #mitochondrial bioenergetic capacity and #β-adrenergic responsiveness. @mark-christian-lab.bsky.social #NTU

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Nikoletta Kalenderoglou @nkalender.bsky.social · 19/05/2026

Our study further demonstrated that #miR-10b-5p regulates later stages of #adipogenesis at least in part through downregulation of #Tubby a direct target of miR-10b-5p. We also found that miR-10b-5p alleviated impaired adipocyte differentiation by suppressing Tubby-mediated #GProteinSignaling. #GPCR

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Nikoletta Kalenderoglou @nkalender.bsky.social · 19/05/2026

Our findings suggest that #miR-10b-5p regulates early #adipogenesis by influencing cell fate bias toward the #paraxialMesoderm lineage through modulation of the #Gata6 / #Bmp2 signaling axis. #NTU_Metabolic #SHIMR_NTU @ntumeta.bsky.social @mark-christian-lab.bsky.social @ntuyourlibrary.bsky.social

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Nikoletta Kalenderoglou @nkalender.bsky.social · 19/05/2026

This study shows that #miR-10b-5p inhibition plays a dynamic role in #AdipocyteBiology, as its inhibitory effects manifest differently during #StemCell #commitment and #adipocyte differentiation. @ntumeta.bsky.social @mark-christian-lab.bsky.social #miRNA #adipogenesis #SHIMR_NTU #NTUMetabolic

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Nikoletta Kalenderoglou @nkalender.bsky.social · 19/05/2026

The final published version of our paper is now available in Cell Communication and Signaling. We investigated how #miR-10b-5p regulates adipocyte lineage commitment and differentiation through targeting of #Gata6 & #Tubby doi.org/10.1186/s129... @mark-christian-lab.bsky.social @jhobbs22.bsky.social

🔗https://link.springer.com/article/10.1186/s12964-026-02834-y

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NTU Metabolism @ntumeta.bsky.social · 08/03/2026

Jasmin Simpson presented research at #SfEBES2026 on how combined maternal and paternal #lowProtein diets affect early embryo development. Mouse embryos from two low-protein parents showed 20% lower #blastocyst survival and altered morphology, linked to disrupted 1C-metabolism. #NTU #SHIMR_NTU

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Nikoletta Kalenderoglou @nkalender.bsky.social · 05/03/2026

Great few days in Harrogate at #SFEBES2026 presenting our work on how miR-10b-5p promotes #BrownAdipocyte differentiation & the #thermogenic program in #WhiteAdipose tissue. Lots of inspiring science and great discussions throughout the #conference. #Metabolism #miRNA @socendocrinology.bsky.social

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NTU Metabolism @ntumeta.bsky.social · 04/03/2026

Antonysunil Adaikalakoteswari presented at #SFEBES2026 on how maternal vitamin #B12 deficiency affects #placental development. Using #multiomics data from the #PRiDE cohort, the study found changes in #DNAmethylation, gene expression and #miRNAs linked to low B12. @socendocrinology.bsky.social

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NTU Metabolism @ntumeta.bsky.social · 03/03/2026

Jacob Hobbs presenting at #SFEBES2026 #conference 🔬 Sharing findings on Tubby as a novel regulator of early #BrownAdipocyte differentiation and its role in #PPAR signalling and #lipolysis Come and say hello, Poster 133 @mark-christian-lab.bsky.social @amandacoutts.bsky.social #NTU #SHIMR_NTU

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Nikoletta Kalenderoglou @nkalender.bsky.social · 02/03/2026

Excited to present our work at #SFEBES2026 on how miR-10b-5p influences adipocyte #differentiation and #thermogenic programming in #WhiteAdipose tissue 🔥 We uncover a novel miR-10b–Tub regulatory axis shaping #BrownAdiposeTissue physiology. #Metabolism #Thermogenesis #miRNA @ntumeta.bsky.social

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NTU Metabolism @ntumeta.bsky.social · 24/02/2026

Super excited to announce The Matrix: Adipose Remodelled 🧬Join us in Nottingham 📍| 7–8 December 2026 🗓️ Register your interest👇 www.biochemistry.org/events-and-t... #NTU #SHiMR_NTU #NTUResearch #NTUMetabolic #Adipose #AdiposeTissue #conference #organoid #metabolism #OMICS #ExtracellularMatrix

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NTU Metabolism @ntumeta.bsky.social · 17/12/2025

@ntumeta.bsky.social and @ntuneuro.bsky.social joined forces for our #ISTeC Dish Party, a celebration of culture, community, and amazing food. Huge thanks to @marwaalkhalidi.bsky.social for the brilliant organisation and unforgettable food performance 👏🍽️ Thanks to everyone who joined! 🙌 #SHiMR_NTU

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NTU Metabolism @ntumeta.bsky.social · 03/11/2025

🎓 Congratulations to Dr. Joshua N. Awoke, PhD AFHEA, on successfully defending his thesis on the role of #carnosine and #inflammation in #metabolic diseases! 👏 Thanks to Dr. Sergio Colombo & Prof. Mark Turner for their support. #SHIMR_NTU #NTUMetabolic

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NTU Metabolism @ntumeta.bsky.social · 30/10/2025

We were delighted to host Prof Delphine Boche ( #SouthamptonUni) for our #SHiMR_NTU Seminar! She shared insights into #neuroinflammation in #Alzheimer’s disease and innovative methods to study #microglial cells in the human brain. Thanks to Dr Shreyasi Chatterjee for hosting! @ntuneuro.bsky.social

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NTU Neuro @ntuneuro.bsky.social · 13/10/2025

💡Big questions and bigger ideas at Friday's Neuroscience-metabolism Journal Club! Hosted by Alex Wilson-Slomkowski, sparking lively debate on how much data is enough for a paper? Brilliant insights, great company and of course, cake 🍰 #NTU #SHiMR #Neuroscience #Metabolism #JournalClub #ScienceChat

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 26/09/2025

This week we welcomed new team member Maisie Smedley on placement from @uniofnottingham.bsky.social BSc Neuroscience who will be working on tissue clearing and mapping hypothalamic networks. We were all busy in the lab this week! @ntuneuro.bsky.social @ntumeta.bsky.social www.Dumbell-lab.com

L-R Maisie, Rebecca, Annabelle and Marwa working at the bench in the lab

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 19/09/2025

Restarting neuro/metabolism #JournalClub with a cake! Will it turn into baking club? (I hope so) @marwaalkhalidi.bsky.social @ntuneuro.bsky.social @ntumeta.bsky.social

Homemade victoria sponge looking a little ...rustic after it was made quite late last night in between MSc thesis marking!

Marwa kicks us off with the paper she picked to present

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 02/09/2025

A great session this morning, thank you to my co-chair Stephen Manchishi and all the speakers Jonathan Johnton, Beatrice Filippi, Chris Coyle and Szilvia Vas and great discussion from the audience. 🧠🎤🍔🕘🐭

Rebecca Dumbell holding a microphone to close the session. In front of a slide "thank you for your attention"

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 02/09/2025

In this afternoon's poster session come and meet Bharat Muthukumar talk about ZFHX3 #metabolic effects and Sam Bennett on mice divergently selected for metabolic differences and altered behavioural #rhythms. #BSNbradford2025 #NTUresearch @bsneuroendo.bsky.social @ntuneuro.bsky.social

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 03/09/2025

What a great conference @bsneuroendo.bsky.social #BSNbradford2025 with team NTU (and Annabelle not in the photo). Showcasing Neuroendocrine NTU! ✔️three posters ✔️one poster prize 🏆 ✔️one session chaired ✔️one presentation to the AGM ✔️a lot of curries eaten 🍛 ✔️some crazy dancing ✔️Lots of cool science

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 01/09/2025

Presenting her work on today's poster session @marwaalkhalidi.bsky.social talking about ZFHX3 and it's molecular action on energy balance neuropeptides @bsneuroendo.bsky.social @ntuneuro.bsky.social @ntumeta.bsky.social #BSNbradford2025

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 02/09/2025

The #DumbellLab on tour! #BSNbradford2025 left-right it's me, Bharat, Marwa @marwaalkhalidi.bsky.social and Annabelle. Posters might be over but chat to us about our work here at the @bsneuroendo.bsky.social annual meeting! www.Dumbell-lab.com @ntuneuro.bsky.social @ntumeta.bsky.social

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 03/09/2025

Well done Sam! Great to see NTU neuroendocrinology highlighted and winning prizes 🏆 #BSNbradford2025 #NTUresearch @bsneuroendo.bsky.social @ntuneuro.bsky.social @ntumeta.bsky.social

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NTU Neuro @ntuneuro.bsky.social · 06/08/2025

🧠 New Research Alert! Dr. Gareth Banks' latest study in Translational Psychiatry highlights the role of the murine ATP-binding cassette transporter Abcc5 (MRP5/cMOAT) in memory consolidation, circadian rhythm regulation, and glutamatergic signalling. 📄 Read the full paper: doi.org/10.1038/s413...

doi.org

The murine ATP-binding cassette transporter C5 (Abcc5/MRP5/cMOAT) plays a role in memory consolidation, circadian rhythm regulation and glutamatergic signalling - Translational Psychiatry

Translational Psychiatry - The murine ATP-binding cassette transporter C5 (Abcc5/MRP5/cMOAT) plays a role in memory consolidation, circadian rhythm regulation and glutamatergic signalling

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NTU Metabolism @ntumeta.bsky.social · 25/07/2025

A huge well done to our incredible PhD graduates from the Metabolic Health team, Dr Laura Lenham, and Dr Jade Creighton. We are proud to celebrate this important milestone with you. #SHIMR_NTU #NTU #NTUMetabolic @ntuneuro.bsky.social #PhD #Graduation #Classof2025

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NTU Neuro @ntuneuro.bsky.social · 15/07/2025

PhD student Zak and Professor Tom Wishart are at the #AnatomicalSociety #cerebralcortex conference in Oxford, presenting their latest research on the role of PpT1 in #Batten disease. Exciting insights from the #NTUneuro and #SHiMR team!🧠🔬 #Neuroscience #Research #PhDLife #MolecularBiology #SciComm

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NTU Metabolism @ntumeta.bsky.social · 18/07/2025

Dr Alice Murphy spoke at the UKHAIC networking event, sharing how her #FTMA grant with Intelligent OMICS Ltd is advancing research into predicting #type2diabetes improvement post-bariatric surgery using urine. Great discussions on #healthyAgeing. #diabetes #NTU #NTUMetabolic #SHiMR_NTU

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 08/07/2025

At the @physoc.bsky.social Physiology of obesity meeting in @uniofnottingham.bsky.social today. Bharat will be presenting his poster this afternoon on ZFHX3 in #BrownFat and metabolism @bsneuroendo.bsky.social @socendocrinology.bsky.social @ntumeta.bsky.social @ntuneuro.bsky.social #NTUresearch

Bharat Muthukumar presenting his poster (blurred)

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

#SHiMR2025 wrapped up with closing remarks from Prof Gareth Lavery, celebrating a day of brilliant science. Congrats to our prize winners:Maria Pia Savoca, Abha Kushwaha & Ollie Megram! Huge thanks to all speakers, chairs & attendees for making it such an inspiring event. #NTU_Metabolic #SHIMR_NTU

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

Highlight of #SHiMR2025: an insightful keynote from Nabil-Fareed Alikhan on #EntericPathogens, #COVID19 genomics, and how #bioinformatics, large-scale #genomics and open software are shaping global #PublicHealth responses. #COGUK #PathogenSurveillance #NTU_Metabolic #BigData #NTU #NTU_Metabolic

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

Session 3 at #SHiMR2025 put the spotlight on #BigData! Chaired by Dr David Boocock, the session opened with Dr David Negus from AROM, who explored how large-scale data can accelerate the search for novel #antimicrobials. #SHIMR_NTU #NTU

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

An inspiring afternoon session at #SHIMR2025 Symposium. Chaired by Dr Marion Hogg, the session began with Professor Tom Wishart offering a look into the proteomic profiling of #synapses, exploring how molecular vulnerability might shape #neurological stability. #SHIMR_NTU @ntuneuro.bsky.social

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

#SHiMR2025 session 1 set the scene for a day of #BigData-powered discovery. From Prof Nik Morton’s opening remarks to an inspiring talk by SHiMR iPrize winner Prof Keeley Brookes on public engagement through the #LEAP, the morning set the tone for a day of science. #NTU_Metabolic #SHIMR_NTU #NTU

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 02/07/2025

It's our Nottingham Trent #SHiMR day symposium today. Starting with Keeley Brookes showcasing our prize-winning work with LEAP - our public #Research #co-creation scheme. Find out more: www.ntu.ac.uk/study-and-co... #NTUResearch @ntuneuro.bsky.social @arom-ntu.bsky.social @ntumeta.bsky.social

Dr Keeley Brookes enthusiastically introducing a colourful slide "Join the conversation. Listen, engage and analyse with the public"

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Dr Rebecca Dumbell @rebeccadumbell.bsky.social · 02/07/2025

A brilliant plenary talk in our #NottinghamTrent #NTUResearch #SHiMR research day is Nabil-Fareed Alikhan of @ox.ac.uk talking about (open) #bigdata. Complete with Blade Runner quotes and highlighting the importance of a hypothesis @ntuneuro.bsky.social @arom-ntu.bsky.social @ntumeta.bsky.social

Prof Nik Morton hosts Dr Nabil-Fareed Alikhan in front of a lectern with title slide "Open data, open minds: bioinformatics and big data lessons from COVID-19 and beyond"

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

Kicking off #SHIMR2025 Symposium, with director of #SHIMR_NTU, Professor Nik Morton, delivering the opening remarks, setting the tone for a day full of exciting research. #NTUMetabolic #NTU #NTU_Research

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NTU Metabolism @ntumeta.bsky.social · 02/07/2025

Excited for #SHiMR2025 kicking off today at NTU’s Newton building! Showcasing cutting-edge translational science — from #bioinformatics & #BigData to #BrainHealth, #Cancer, #metabolism & #PublicEngagement (#LEAP). #SHIMR_NTU #NTUMetabolic #NTU

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NTU Metabolism @ntumeta.bsky.social · 26/06/2025

This week we were thrilled to host Dr Adam Watkins (‪@sheffielduni.bsky.social‬) at #SHIMR_NTU! He shared fascinating insights into how #PaternalDiet impacts #sperm, the #MaternalEnvironment & #OffspringHealth. #SpermHealth Thanks to Dr Adaikala Antonysunil for hosting! 👏 #NTUMetabolic

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