Reposted by Nicolas PanayotisKeri Martinowich @martinowk.bsky.social · 13/09/2026Epinephrine producing neurons in the locus coeruleus (LC) are among the earliest cells affected in Alzheimer’s disease, and yet we know remarkably little about their molecular biology in human 🧠, in part due to technical challenges because the LC is tiny and really difficult to profile. 2225
Nicolas Panayotis @npanayotis.bsky.social · 14/09/2026Les 12h30 de la Recherche sont de retour @ipnp.bsky.social ! Premier épisode de la saison 2026/2027 le 29 Septembre ! Au menu: "Sclérose en plaques : remyéliniser grâce à l’activité électrique" www.ghu-paris.fr/fr/agenda/12... @inserm.fr @cnrsbiologie.bsky.social @upcite.bsky.social 021
Reposted by Nicolas PanayotisSaints-Pères Paris Institute for the Neurosciences @sppin-cnrs.bsky.social · 11/09/2026@sppin-cnrs.bsky.social @cnrs.fr is organizing #NeuralNet2026 in Paris on Nov. 25–27 ! Join the 15th annual meeting of GDR NeuralNet @upcite.bsky.social , bringing together researchers working across systems neuroscience, neural data, computational modeling, NeuroAI & data science. 1169
Reposted by Nicolas Panayotisjcroux.bsky.social @jcroux.bsky.social · 10/09/2026Et si, dans le syndrome de Rett, nous regardions aussi du côté de l’intestin ? Dans cette étude, nous mettons en évidence dans un modèle murin du syndrome de Rett une importante perturbation de la voie cholinergique du système nerveux entérique. www.sciencedirect.com/science/arti... 021
Nicolas Panayotis @npanayotis.bsky.social · 09/09/2026Apocalypse? Nah! Part I – future tense journals.biologists.com/jcs/article/...journals.biologists.comApocalypse? Nah! Part I – future tenseI miss the honky-tonks, Dairy Queens and 7-Elevens. (You've got it, you've got it.) And as things fell apart, nobody paid much attention.I've had this song running through my head for a few days. It's... 100
Nicolas Panayotis @npanayotis.bsky.social · 04/09/2026Impatient de participer une nouvelle fois aux 38èmes Journées Nationales du Syndrome de Rett #JNSR organisées par @afsr.bsky.social les 10 & 11 octobre 2026 à Paris. afsr.fr/nos-actions/... @sppin-cnrs.bsky.social @cnrsbiologie.bsky.social @upcite.bsky.social 021
Nicolas Panayotis @npanayotis.bsky.social · 31/08/2026May her memory be a blessing 🙏 What a woman and scientist she was! A huge loss for all the Weizmann community. 010
Reposted by Nicolas PanayotisINMED @inmed.bsky.social · 27/08/2026 With profound sadness we announce the passing of our colleague and friend Antoine de Chevigny, an expert in cortical development respected for his creativity and curiosity and cherished for his kindness and joie de vivre. He leaves an immense void. Support for his partner: tinyurl.com/2yrh7huc 175
Reposted by Nicolas PanayotisCNRS Biologie @cnrsbiologie.bsky.social · 23/07/2026#ResultatScientifique🔎| Marcher sur un terrain irrégulier exige une adaptation permanente des mouvements 🧠 ✍️ @uligraupner.bsky.social 📕 @natcomms.nature.com buff.ly/NC8iCr7insb.cnrs.frQuand le cervelet orchestre la précision de chaque pasMarcher sur un 165
Nicolas Panayotis @npanayotis.bsky.social · 20/07/2026As a famous German player said : FOOTBALL WON ! www.youtube.com/watch?v=IPSf...youtube.comMANOLO ESCOBAR !Y VIVA ESPAÑA! EN DIRECTO (1972)YouTube video by VICTOR ENGUIDANOS SEQUERO 000
Nicolas Panayotis @npanayotis.bsky.social · 10/07/2026📢 We are recruiting an M2 Master's student for a 6-month internship (Jan. 2027) in my lab at @sppin-cnrs.bsky.social @cnrs.fr | @upcite.bsky.social . The project focuses on developing optimized molecular therapies for #RettSyndrome. Details are in the attached description. Please share! 032
Reposted by Nicolas PanayotisMichael Graupner @uligraupner.bsky.social · 10/07/2026Kudos to Margaux on a fantastic first poster presentation at #FENS2026 in Barcelona! 🎉 The work sparked great discussions and received excellent feedback—an outstanding first big conference presentation! @sppin-cnrs.bsky.social 041
Reposted by Nicolas PanayotisSaints-Pères Paris Institute for the Neurosciences @sppin-cnrs.bsky.social · 07/07/2026Shout out to our @upcite.bsky.social Neuroscience Master’s students now in Barcelona for #FENS2026! 🧠✨ Supported by Neuroscience Graduate School grants, they’re ready for a week of science, networking, and discovery and will share their highlights at the September kick-off meeting. 031
Reposted by Nicolas PanayotisWeizmann Institute of Science @weizmann.ac.il · 21/06/2026Welcome to the official Bluesky account of the Weizmann Institute of Science. Here we share scientific discoveries, research news, and stories from our scientists. 0113
Nicolas Panayotis @npanayotis.bsky.social · 17/06/2026Full room at the Genother summit 2026 at the Maison de L'océan! Glad I could arrive on time for Nicolas Levy's lecture on ASOs 😉 020
Nicolas Panayotis @npanayotis.bsky.social · 12/06/2026Pourquoi les os sont-ils fragiles dans le syndrome de Rett ? afsr.fr/actualites/p... @afsr.bsky.social 011
Reposted by Nicolas PanayotisEMBO @embo.org · 10/06/2026Learn about #axon regulation in the EMBO | The Company of Biologists Workshop "Axonal degeneration and regeneration" in Onna-son, Japan, 18–22 October 2026. Deadline: 21 June 2026 meetings.embo.org/event/26-axonal-d… #EMBOAxonalRegeneration #EMBOevents #meeting 🧪 0134
Nicolas Panayotis @npanayotis.bsky.social · 30/05/2026Some transfers are impossible. Others happen because your son negotiates better than any sporting director. Aller Paris ! 😉 010
Nicolas Panayotis @npanayotis.bsky.social · 18/05/2026Présentation prête pour le festival Pint of Science #Pint26 ce soir à L'imprévu Café - 9 Rue Quincampoix, Paris 4. 122
Reposted by Nicolas PanayotisSaints-Pères Paris Institute for the Neurosciences @sppin-cnrs.bsky.social · 30/04/2026La science ne compte que si elle est partagée. Merci à AFSR d’avoir relayé ce billet vulgarisé par nos chercheurs sur les thérapies moléculaires du syndrome de Rett. SPPIN reste engagé à rendre les résultats accessibles et utiles, au plus près des associations de patients ! afsr.fr/le-syndrome-... 021
Nicolas Panayotis @npanayotis.bsky.social · 29/04/2026Increased Osteoclast Activity Contributes to Bone Resorption and Osteopenia in a Rett Syndrome Mouse Model. www.biorxiv.org/content/10.6... 232
Nicolas Panayotis @npanayotis.bsky.social · 26/04/2026Arrivé au stade pour @parisfc.bsky.social x LOSC 020
Nicolas Panayotis @npanayotis.bsky.social · 23/04/2026Nice work published in #Neurotherapeutics by the Gaiarsa team at @inmed.bsky.social showing how Leptin antagonism improves Rett syndrome phenotype in the symptomatic Mecp2-deficient mice. Congrats to Yasmine, Jean-Luc and all the team 👏 www.neurotherapeuticsjournal.org/article/S187...neurotherapeuticsjournal.orgLeptin antagonism improves Rett syndrome phenotype in symptomatic Mecp2-deficient miceRett syndrome (RTT) is a severe X-linked neurodevelopmental disorder caused by mutations in MECP2. Elevated circulating levels of the adipocyte hormone leptin are consistently observed in patients and... 031
Nicolas Panayotis @npanayotis.bsky.social · 22/04/2026Jetzt geht's los ! On the way back from a wonderful Strasbourg under wonderful weather ! ;-) 000
Reposted by Nicolas PanayotisPhilip Freund @philipfreund.bsky.social · 21/04/2026Thank you @bpodaily.bsky.social for the feature! I love this image. It captures some of the major processes that shape synaptic plasticity, learning, and memory. Synaptic vesicles, microtubule intrusions into the dendritic spine, clear synaptic cleft and PSD. 023
Reposted by Nicolas PanayotisBiomedical Picture of the Day BPoD @bpodaily.bsky.social · 21/04/2026Importin β1's role in presynaptic vesicles of hippocampal neurons for spatial memory 📷 @philipfreund.bsky.social @npanayotis.bsky.social et al @weizmanninstitute.bsky.social in @science.org Signaling ➡️ bpod.org.uk/archive/2026... with John Ankersbpod.org.ukBPoD | Getting the MessageGetting the Message - Biomedical pictures for April 2026. 152
Nicolas Panayotis @npanayotis.bsky.social · 16/04/2026Algerian olive oil that could be straight from the strait of Ormuz ⛽ 010
Nicolas Panayotis @npanayotis.bsky.social · 13/04/2026Here it is, hot off the press ;-) "From Gene to Hope: Rett Syndrome and the Rise of Molecular Therapies" published in Molecular Diagnosis & Therapy You can already read it at this link: link.springer.com/epdf/10.1007... Thanks to all coauthors and congrats again @yleblay.bsky.social 👏👏👏 2103
Nicolas Panayotis @npanayotis.bsky.social · 13/04/2026Billeterie ouverte depuis ce matin pour #Pint26 Ici le lien pour notre évenement à Paris: pintofscience.fr/event/repare...pintofscience.frRéparer, explorer : le cerveau en actionVenez explorer les mystères du cerveau ! Des thérapies géniques à la réalité virtuelle, Nicolas et Pascale vous montreront comment les scientifiques étudie… 031
Reposted by Nicolas PanayotisJoao Barbosa @jbarbosa.org · 03/04/2026Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr 212771
Reposted by Nicolas PanayotisParis-Saclay Institute of Neuroscience @neuropsi.bsky.social · 03/04/2026🧠 Today we announce the first keynote speaker of the "New Horizons in Aging and Neurodegenerative Diseases": Viviana Gradinaru, professor in Neuroscience and Biomedical Engineering at Clatech. ▶️ Register, submit an abstract: www.cheninstitute.org/events-new/n... 042
Nicolas Panayotis @npanayotis.bsky.social · 30/03/2026Speaking at @pintofscience.fr #Pint26 on May 18th ! I’ll be discussing about #Rettsyndrome, how too little or too much of #MECP2 disrupts (too many) brain functions and how gene therapies can benefit from self-regulated systems. More info at : pintofscience.fr/event/repare...pintofscience.frRéparer, explorer : le cerveau en actionVenez explorer les mystères du cerveau ! Des thérapies géniques à la réalité virtuelle, Nicolas et Pascale vous montreront comment les scientifiques étudie… 084
Reposted by Nicolas PanayotisYoann Leblay @yleblay.bsky.social · 26/03/2026Well that's the first paper with my name on it 😎 very proud of us! 264
Nicolas Panayotis @npanayotis.bsky.social · 26/03/2026Paper accepted selfie ! First paper (a review) by @yleblay.bsky.social - Stay tuned ;-) 172
Reposted by Nicolas PanayotisMike Fainzilber @mfainzilber.bsky.social · 25/03/2026🧪 When an mRNA has not one or two, but at least THREE localization signals, suggesting that mTOR mRNA requires robust localization. See our preprint, lead by Nitzan Samra with greatly appreciated collaborations with @sahoolab.bsky.social and the Jeffery L. Twiss lab www.biorxiv.org/content/10.6...biorxiv.org 084
Reposted by Nicolas PanayotisPabi Sahoo @sahoolab.bsky.social · 25/03/2026How many axon localization elements are in one mRNA? mTor mRNA seems to have at least 3. Read this interesting preprint from the @mfainzilber.bsky.social lab. Multiple mTOR RNA localization signals regulate subcellular protein synthesis and axonal growth www.biorxiv.org/content/10.6...biorxiv.org 053
Nicolas Panayotis @npanayotis.bsky.social · 25/03/2026The coffee setup has been updated in the office. 030
Reposted by Nicolas PanayotisNew Scientist @newscientist.com · 24/03/2026The neurodegenerative condition chronic traumatic encephalopathy appears to be driven by damage to the blood-brain barrier due to repetitive head injuries, like those that occur in boxing. This suggests that drugs that strengthen this barrier could prevent or slow the conditionnewscientist.comBoosting the blood-brain barrier could avert brain damage in athletesThe neurodegenerative condition chronic traumatic encephalopathy appears to be driven by damage to the blood-brain barrier due to repetitive head injuries, like those that occur in boxing. This suggests that drugs that strengthen this barrier could prevent or slow the condition 021
Nicolas Panayotis @npanayotis.bsky.social · 13/03/2026It's raining in Paris and I am writing my HDR. youtu.be/LkDLQ1lZc5o?...youtu.beJim Hall - Concierto de AranjuezYouTube video by 239712A 010
Nicolas Panayotis @npanayotis.bsky.social · 07/03/2026Timely collection of Jafar Panahi's movies on Mubi: mubi.com/fr/fr/collec...mubi.comLE CINÉMA PAR TOUS LES MOYENS : UNE RÉTROSPECTIVE JAFAR PANAHIVoyez le meilleur du cinéma, où que vous soyez. Des films de partout dans le monde, de nouveaux réalisateurs comme de cinéastes récompensés. Regardez-les en streaming, ou téléchargez-les pour les visi... 000
Nicolas Panayotis @npanayotis.bsky.social · 05/03/2026Maman comes back from Roma and she knows what gifts to bring back to papa and Yuri 😉 (Ok-ok I like the Panini album too) 010