Intrinsically disordered regions (IDRs) play key roles in cellular signaling and regulation, yet their contribution to human disease remains poorly un…

Intrinsically disordered regions (IDRs) play essential roles in signaling and regulation but remain under-characterized in the context of human disease. We analyzed nearly one million ClinVar missense...

Intrinsically disordered regions (IDRs) play critical roles in various cellular processes, often mediating interactions through disordered binding reg…

AbstractSummary. Accurate pathogen identification is crucial during outbreaks, especially with the emergence of new variants requiring frequent primer upda

Intrinsically disordered proteins (IDPs) lack a stable three-dimensional structure under physiological conditions, challenging traditional structure-b…