iiinova — where your digital self keeps evolving

Reposted by Noura Maziak

Chema Martin @chemamd.bsky.social · 19/05/2026

🚨 We discovered a new mode of Hox gene regulation in annelids! 🪱 A distal enhancer acts as a "global control region", lifting Hox genes from Polycomb repression. This is reminiscent of Hox gene control in vertebrates, but the two modes likely evolved convergently. www.biorxiv.org/content/10.6...

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Reposted by Noura Maziak

Nicola Rennie @nrennie.bsky.social · 29/04/2026

📊 Five #ggplot2 functions I wish I'd known about earlier 📊 I've written a short blog (with examples) of some of the lesser-known {ggplot2} functions and arguments that make it easier to create better charts! Link: nrennie.rbind.io/blog/five-gg... #RStats #DataViz

nrennie.rbind.io

Five ggplot2 functions I wish I’d known about earlier – Nicola Rennie

There are a few small tweaks you can make to your ggplot2 code to improve your charts. However, they’re not often mentioned. So here’s a few functions and arguments I wish I’d known about earlier.

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Reposted by Noura Maziak

Tobias Warnecke @tobiaswarnecke.bsky.social · 08/04/2026

I wrote an essay. It’s about gain-of-function mutations. And penguins. Also ion channels, chihuahuas, the film Alien, recycled cardboard, and the Apollonian mind. Oh, and muffins. Thanks to the editors of #GENETICS @genetics-gsa.bsky.social for letting me take some stylistic liberties. 1/2

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Reposted by Noura Maziak

Mariko Bennett @nachoriko.bsky.social · 24/03/2026

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

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Noura Maziak @nmaziak.bsky.social · 15/03/2026

A nice thing happened.. We got the cover of Nature Genetics! 😊🎉 The spheres trace nuclear stages through early embryogenesis, with color bursts capturing the diverse events that shape genome architecture. Art done by my friend and very talented artist @christophewirtz.bsky.social 🎨

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Noura Maziak @nmaziak.bsky.social · 10/03/2026

Excited to share my PhD work! The question: How is genome organization established? Here, we developed a low-input Micro-C method, Pico-C, and used it to map chromatin architecture across early stages of fly development. Here’s a quick Blue-torial 🙂 (1/n) www.nature.com/articles/s41...

nature.com

Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila - Nature Genetics

Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.

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Reposted by Noura Maziak

Damir Baranasic @da-bar.bsky.social · 24/02/2026

Congratulations to @nmaziak.bsky.social, @vaquerizasjm.bsky.social et al: Pico-C (low-input Micro-C) shows 3D genome architecture reorganises before major zygotic genome activation in Drosophila, with early loop formation and stronger insulation. @natgenet.nature.com: www.nature.com/articles/s41...

nature.com

Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila - Nature Genetics

Pico-C, a low-input Micro-C approach, reveals that dynamic three-dimensional genome folding precedes zygotic genome activation in Drosophila.

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Reposted by Noura Maziak

Daniel Ibrahim @danielibrahim.bsky.social · 27/05/2025

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

rdcu.be

Conservation of regulatory elements with highly diverged sequences across large evolutionary distances

Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

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Noura Maziak @nmaziak.bsky.social · 08/12/2024

I never expected my first post here to be anything but science, yet today we celebrate the fall of a regime that’s brought decades of pain. The joy of this moment is worth sharing a thousand times over.

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