Reposted by Niall McLoughlinWilson Lab @wilsonlab.bsky.social · 03/06/2026www.nature.com/articles/s41...nature.comA natural depsipeptide antibiotic binds the E-site of the bacterial ribosome - NatureImproved fractionation strategies can identify antibiotics with previously unseen scaffolds and mechanisms, exemplified by manikomycin from Streptomyces rimosus, which acts by targeting the E-site of ... 1269
Niall McLoughlin @niallmcl.bsky.social · 18/03/2026Absolutely fascinating back-to-back papers in NAR showing how an approved kinase inhibitor can specifically and selectively bind HIV TAR RNA and disrupt its downstream activity 041
Reposted by Niall McLoughlinM. Eugenio Vazquez @glowsticks.bsky.social · 06/05/2025We’re looking for candidates to join our lab at @ciqus.bsky.social for a Marie Skłodowska-Curie Postdoctoral Fellowship! bit.ly/4k3uBJn 🧑🏻🔬👩🏻 If you’re into molecular photophysics,💡 peptide engineering, and rethinking the nature of fluorescence—read on. #MSCA2025 #ChemSkybit.lyEU Funding & Tenders PortalThe Funding and Tenders Portal is the single entry point (the Single Electronic Data Interchange Area) for applicants, contractors and experts in funding programmes and procurements managed by the Eur... 133
Niall McLoughlin @niallmcl.bsky.social · 02/04/2025We are recruiting for a summer internship position focused on developing PFAS-free peptide cleavage methods for large scale manufacturing. If you know a recent grad or Master's student looking for some industry experience in Basel this summer, check out the link here www.linkedin.com/jobs/view/41...linkedin.comRoche hiring Internship IP2TIS 2025 - For students in the field of Green Peptide Chemistry in Basel, Basel, Switzerland | LinkedInPosted 6:52:55 AM. At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture…See this and similar jobs on LinkedIn. 040
Reposted by Niall McLoughlinStephan Hacker @stephanhacker2.bsky.social · 25/03/2025Great talk by Brecht Ellenbroek from the group of @sebastianpomplun.bsky.social of the @led3hub.bsky.social at #Lunteren. He talked about the importance of MYC in cancer and their approach to target this pathway using the cell-penetrant miniprotein DuoMYC. onlinelibrary.wiley.com/doi/10.1002/... 042
Reposted by Niall McLoughlinMichael Booth @drmikebooth.bsky.social · 13/12/2024The one time @theguardian.com could rightly use a left-handed DNA image... and they choose right-handed 🤦🏻♂️🤦🏻♂️🤦🏻♂️ @iansample.bsky.social 313322
Reposted by Niall McLoughlinestella newcombe @estellaan.bsky.social · 27/11/2024We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered??? www.nature.com/articles/s41...nature.comStereochemistry in the disorder–order continuum of protein interactions - NatureStudies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex. 717763
