Obesity and mental health challenges have both reached epidemic levels, posing considerable public health concerns that increasingly affect young people.1,2 Roughly half of all mental disorder cases emerge during childhood and adolescence,3 with subclinical symptoms being even more prevalent. The Developmental Origins of Health and Disease framework suggests that periods of rapid physical growth are especially sensitive to external influences and insults.4 Given that accelerated growth and substantial psychosocial changes occur during adolescence, this developmental stage may represent a critical window for the emergence and consolidation of the relationship between obesity and mental health challenges.5 Therefore, it is essential to understand if and how these associations change with age in order to clarify how the dynamic relationship between mental health and weight development evolves across adolescence. So far, this has remained poorly understood. Previous research on mental health and physical growth has primarily focused on psychological distress, such as depression or anxiety, and the risk of obesity, with substantial evidence supporting their co-occurence.6,7,8,9,10 Two meta-analyses summarizing longitudinal studies in adolescents concluded that particularly females with depressive symptoms have an elevated risk of obesity over varying follow-up periods.9,10 This finding is corroborated by another systematic review.11 Anxiety, another indicator of psychological...

Extended Data Fig. 1 Wasserstein distances between external, target, and deployment cohorts before and after covariate-shift adjustment across 20 diseases. Wasserstein distances were used to quantify covariate distribution differences between the external, target and deployment cohorts across 20 chronic disease datasets. Points connected by horizontal lines compare distances before and after covariate-shift adjustment. Abbreviations: HF, heart failure; MI, myocardial infarction; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; T2DM, type 2 diabetes mellitus; CKD, chronic kidney disease. Source data Extended Data Fig. 2 Weight distributions and normalized effective sample size for density-ratio weighting across all diseases in NHANES and SSACB. Box plots show the normalized density-ratio weights used to align the external and target training datasets with the calibration subset of the deployment population for each disease in a, NHANES and b, SSACB. Disease-specific sample sizes are provided in Supplementary Tables 11 and 32. Weights were normalized to have a mean of 1, and the y-axis is shown on a log10 scale. ESS/n denotes the normalized effective sample size, with higher values indicating more stable weights and smaller effective sample size loss. In each box plot, the centre line denotes the median, box bounds denote the first and third...

People aged 60 and over face dangers to their health from exposure to heat at much lower temperatures than previously thought, research has found. Older adults will bear the brunt of increasingly frequent sustained spells of extreme heat globally as the world continues to warm up, according to a study in The Lancet Public Health. Heatwaves will leave huge and growing numbers of people worldwide of all ages suffering from uncompensable heat stress (UHS) – where the body loses the ability to cool itself – and thus at risk of serious damage to their health, including death. “Our results suggest accounting for age stratified vulnerability, intolerable heat will be experienced at much larger scales and for longer durations, affecting far more people than previously thought,” according to the study, which was led by health academics from Stanford University in California. Older adults are known to be more in danger because of the effects of very high temperatures. They sweat less, their hearts work harder in the heat and their blood vessels are less able to widen, limiting their capacity to stay cool. However, previous studies did not properly set out the different risks faced by younger people aged 15-39, middle-aged...

The Authors are grateful to project PID2023-149764OA-I00 funded by MCIN/AEI/10.13039/ 501100011033 and FEDER, EU. The authors are also grateful for the support received from Consolidated DI project nº 039.317/2023, PUCV, Chile. This work was partially supported by CSIC (Comisión Sectorial de Investigación Científica) of the Universidad de la República, in Montevideo, Uruguay, and PEDECIBA – Física, Uruguay. The Authors are grateful to FONDECYT Project No.: 1220107, Millennium Institute on Green Ammonia as Energy Vector, MIGA, ICN 2021–023, Chile and ANILLO ACT240020 Project, Chile. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence...

If you or someone you know is in crisis, please call, text or chat with the Suicide and Crisis Lifeline at 988, or contact the Crisis Text Line by texting TALK to 741741. The trial of a Boston-area mother charged with murdering her three small children in 2023 is leading to calls to improve postpartum mental health care. While the prosecution paints her as a deliberate killer, Lindsay Clancy's defense team argues she was in the grips of severe postpartum psychosis, and didn't receive proper medical care. The unrelenting national attention on the Clancy trial has been difficult for people who've had postpartum psychosis, says Meghan Cliffel who experienced the disorder and is now a mental health advocate. She says many women believe that sheer luck prevented a similar disaster from happening to them. For ongoing coverage of the Lindsay Clancy trial, visit WBUR. Advocates like Cliffel say the case highlights gaps in mental health care for new mothers and the urgent need for more research and public education about a rarely discussed but severe illness. Doctors emphasize, if diagnosed correctly, it's treatable and patients can go on to live normal lives. 'In a deluded reality' Cliffel's psychosis started suddenly,...

Newswise — Harmful algal blooms are becoming more frequent and widespread as warming, eutrophication, agricultural runoff, aquaculture, and wastewater alter freshwater ecosystems. Once a bloom is visible, treatment can be costly, ineffective, or environmentally disruptive, making early warning essential. Yet many forecasting systems work at daily or weekly resolution, rely on fixed thresholds, or return only one predicted value without showing uncertainty. Deep-learning models may improve accuracy, but their decision processes often remain difficult to interpret, especially when drivers change rapidly before bloom onset. These gaps point to a need for in-depth research to develop high-frequency forecasting systems that quantify risk and explain when and why harmful algal blooms may emerge. The study was conducted by researchers from Beijing Institute of Technology, China University of Mining and Technology, and the Research Center for Eco-Environmental Sciences of the Chinese Academy of Sciences. Published (DOI: 10.1016/j.ese.2026.100733) online on July 21, 2026, in Environmental Science and Ecotechnology, the work introduces BloomNet as a multi-horizon forecasting system for harmful algal blooms. The model combines historical water-quality observations with environmental information available over the forecast window, producing hourly algal-density predictions for the next 24, 48, and 72 hours together with interpretable indicators of uncertainty and...

Howard County Executive Calvin Ball announced some funding help for Grassroots when feds pulled funding, but a huge gap remains.