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Neelima Sharma

@neelimasharma.bsky.social
192 followers 307 following 8 posts

Group Leader/Assistant Professor@UCL. Previous:Postdoc@Shubin Lab at UChicago, PhD@Venkadesan Lab at Yale University. Intrigued by the role of mechanics in the development and evolution of morphology and control.

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Reposted by Neelima Sharma
Terence Tao @teorth.bsky.social · 11/09/2026
A group of 25 Fields Medalists, including myself, have made a joint declaration on Math and AI: mathandai.org . We welcome additional signatories. See also this article in the Economist announcing the declaration: www.economist.com/science-and-...
mathandai.org
Declaration — Math and AI
Read the declaration and add your name.
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Vicky & The Sleight Lab @vs-marine.bsky.social · 27/07/2026
Please share, I am hiring an evo devo postdoctoral research fellow! 📍: The Sleight Lab, University of Aberdeen, Scotland (5th oldest University in UK & English-speaking world) 📅: start after 1st December 2026 🐌: Evolution and Development (molluscs) ⌛: 3 year contract sleightlab.com/vacancies/
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Ryan N. Felice @rnf.bsky.social · 01/06/2026
Hey look: A job! @echinerd.bsky.social and I are looking for a research technician to work on sea urchin development. If you are good at segmenting CT scans and want a chance to work on some super cool organisms, this job here at UCL is for you! apply now: bit.ly/4o2qccY
CT scan of a juvenile sea urchin
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Alain Goriely @alaingoriely.bsky.social · 15/05/2026
I am looking for a Post-doc in Oxford to work with me on morphogenesis at the cellular scale, with particular emphasis on growth processes and their mechanical and dynamical consequences. Please circulate my.corehr.com/pls/uoxrecru... This bristle is created by a single cell! Let's model it.
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Berta Verd @bertaverd.bsky.social · 21/04/2026
New Pre-Print Alert! Evolving initial conditions: an alternative developmental route to morphological diversity with Shannon Taylor and @jamesehammond.bsky.social www.biorxiv.org/content/10.6...
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drphilcox.bsky.social @drphilcox.bsky.social · 30/03/2026
Postdoc advert now live! Come and work with me at the UCL Centre for Integrative Anatomy @ucl-c4ia.bsky.social on the Mediterranean Neogene insular giant fauna. You'll also get to work with a great team: @toriherridge.bsky.social @nannonstevens.bsky.social and Jesse Hennekam
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Neelima Sharma @neelimasharma.bsky.social · 16/03/2026
I talked with Jorge Cham (!) about synovial joints, and considering how much I enjoyed reading PhdComics during my early career, it was a real treat to talk with him ✨:
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Zena Hadjivasiliou @zenahadjivasiliou.bsky.social · 23/02/2026
Spring PhD recruitment round @crick.ac.uk is now open and we have a project on offer: www.crick.ac.uk/careers-stud.... If you have a background in maths or physics and are curious about patterning and growth in biology this could be the project for you! Please help us spread the word 💥
crick.ac.uk
Hadjivasiliou Lab | Patterning in dynamic environments
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Neelima Sharma @neelimasharma.bsky.social · 03/02/2026
Why is it that small animals like insects have a landspace body plan when viewed head-on, but larger animals like elephants are taller than wide? With @m-v.bsky.social, we find out in our new preprint titled 'Size and shape of terrestrial animals' - arxiv.org/html/2602.00...
an insect, a bird, and an elephant visualized with unit height scaling. insect is landscape shaped and the elephant is portrait shaped
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tdcapellini.bsky.social @tdcapellini.bsky.social · 27/08/2025
1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...
nature.com
The evolution of hominin bipedalism in two steps - Nature
The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...
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Sam England @samjakeengland.bsky.social · 24/07/2025
Why do treehoppers look so weird?! Our latest paper, out this week in @pnas.org, suggests a perhaps unexpected reason - static electricity ⚡ We show that treehoppers can detect the electrostatic cues of predators and that their crazy shapes may boost their electrosensitivity! doi.org/10.1073/pnas...
doi.org
Electroreception in treehoppers: How extreme morphologies can increase electrical sensitivity | PNAS
The link between form and function of an organism’s morphology is usually apparent or intuitive. However, some clades of organisms show remarkable ...
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Sergio Menchero @sermenchero.bsky.social · 24/07/2025
Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...
cell.com
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs
Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...
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SeppeKuehnLab @seppekuehnlab.bsky.social · 17/07/2025
New paper in @nature.com! With @kiseokmicro.bsky.social , Siqi Liu, Kyle Crocker, Jojo Wang, Mikhail Tikhonov & Madhav Mani — a massive dataset and simple model reveal a few conserved regimes that capture how soil microbiome metabolism responds to perturbations. www.nature.com/articles/s41...
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Matteo Fabbri @mfabbri.bsky.social · 09/07/2025
New paper today about the evolution of the wrist along the dinosaur to bird transition: a bird-like configuration appeared in predatory dinosaurs first, as suggested by new exceptionally preserved hands of oviraptors and troodontids www.nature.com/articles/s41...
nature.com
Reorganization of the theropod wrist preceded the origin of avian flight - Nature
The forelimbs of two Late Cretaceous theropod dinosaurs show the presence of the pisiform bone, previously thought to have been lost early in theropod evolution and regained in birds during the evolut...
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Neil Shubin @neilshubin.bsky.social · 21/05/2025
New paper from the lab: Our teeth arose as sensory organs on the outside of the body of ancient jawless fish.!! Congrats to Yara Haridy and the team! Background and video: phys.org/news/2025-05... Open Access Paper: www.nature.com/articles/s41... News and Views: www.nature.com/articles/d41...
phys.org
Teeth first evolved as sensory tissue in the armored exoskeletons of ancient fish, fossil scans find
Anyone who has ever squirmed through a dental cleaning can tell you how sensitive teeth can be. This sensitivity gives important feedback about temperature, pressure—and yes, pain—as we bite and chew ...
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Manuel Razo @mrazo.bsky.social · 15/05/2025
1/n 🧵 Excited to share our new paper! We developed a framework to reveal hidden simplicity in how organisms adapt to different environments, particularly focusing on antibiotic resistance evolution. #EvolutionaryBiology #MachineLearning
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Neelima Sharma @neelimasharma.bsky.social · 06/05/2025
Got the opportunity to write a `behind the paper' story for @the-node.bsky.social about our work on the evolution of synovial joints, and I thoroughly enjoyed the experience. Here it is, for some leisure reading:
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Madhu Venkadesan @m-v.bsky.social · 04/03/2025
The incredible Henry Bennet-Clark passed away recently, but his wonderful science will continue to inspire. www.stcatz.ox.ac.uk/dr-henry-ben... He wrote numerous amazing papers, including on how fleas jump so high: scholar.google.com/scholar?q=au... #biomechanics #obituary #stcatz
stcatz.ox.ac.uk
Dr Henry Bennet-Clark (1934–2025) - St Catherine's College
Dr Henry Bennet-Clark (1934–2025) St Catherine’s College is deeply saddened to announce the passing of Dr Henry Bennet-Clark, Emeritus Reader...
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Tetsuya Nakamura @nakamuralab.bsky.social · 27/02/2025
Started from ontogenetic and molecular studies of living lineages, authors found reciprocally cavitated joints in placoderms. Placoderms can move pectoral fins very smoothly!! Congrats @neelimasharma.bsky.social @neilshubin.bsky.social Yara Haridy! #Teamfish #evodevo
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PLOS Biology @plosbiology.org · 26/02/2025
When did the lubricated joints that allow our skeleton to swivel, rotate and bend evolve? @crumplab.bsky.social explores a new @plosbiology.org paper by @neelimasharma.bsky.social &co that pinpoints their origin to the earliest jawed vertebrates 🧪 Paper: plos.io/3CTC8La Primer: plos.io/4kkhXa6
Left: A phylogeny of chordates, flanked by images of a lamprey, a placoderm, a brown shark, a longnose gar and a hawksbill turtle. Agnathans such as lampreys lack synovial joints. The first putative evidence of synovial joints in the fossil record is in early gnathostomes such as the antiarch placoderm fish that lived during the Silurian and Devonian periods. Modern gnathostomes such as cartilaginous fishes (i.e., chondrichthyans such as the brown shark), bony fishes (i.e., osteichthyans such as the longnose gar), and limbed vertebrates (i.e., tetrapods such as the Hawksbill turtle) possess synovial joints in their jaws, fins/limbs, and other locations. All images used are freely available without copyright restrictions. Top right: a typical agnathan joint is shown where glycosaminoglycans and proteoglycans are uniformly distributed across the cartilages (blue) that are connected by fibrous tissue (olive). Bottom right: a typical gnathostome synovial joint is shown where surface cartilage has a unique proteoglycan composition from the underlying cartilage and bone, and a fluid-filled cavity separates adjacent skeletal elements.
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Neelima Sharma @neelimasharma.bsky.social · 26/02/2025
Super excited to share our @plosbiology.org paper with @neilshubin.bsky.social and Yara Haridy, “Synovial joints were present in the common ancestor of jawed fish but lacking in jawless fish” Paper: plos.io/3CTC8La Primer by @crumplab.bsky.social: plos.io/4kkhXa6 I hope you enjoy reading it!
plos.io
Synovial joints were present in the common ancestor of jawed fish but lacking in jawless fish
Synovial joints are characterized by lubricated articular surfaces separated by a cavity, providing mobility and load-bearing, but when did they evolve? This comparative and developmental study reveal...
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PLOS Biology @plosbiology.org · 25/02/2025
When did synovial joints evolve? @neelimasharma.bsky.social @neilshubin.bsky.social &co reveal that stable, mobile & lubricated joints were present in the common ancestor of jawed fishes but lacking in jawless ones 🧪 @plosbiology.org plos.io/3CTC8La
Top: Immunostaining reveals aggrecan (yellow) at the articular surfaces in the pelvic joint of an embryonic little skate (stage 33). The nucleus is stained using DAPI and is shown in red. Bottom: Phylogenetic tree adapted from Donoghue and Keating, annotated to show that synovial joints exist in extant jawed vertebrates (gnathostomes), but the study’s results do not support their existence in cyclostomes. The presence of reciprocally shaped and cavitated joints in the dermal skeleton of antiarchs suggests that joints that function by relative sliding (similar to synovial joints) first originated in stem gnathostomes.
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Neil Shubin @neilshubin.bsky.social · 25/02/2025
New paper led by @neelimasharma.bsky.social on the lab! The evolutionary origin of highly mobile joints!
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