The rise of time-resolved macromolecular crystallography has been accompanied by renewed interest in companion biophysical characterization methods applicable to molecules both in solution and in crys...

Both global and specific radiation damage have been investigated using three different proteins at cryogenic and room temperature. The large decoupling between global and specific radiation damage at ...

We used on-line in crystallo UV–Vis absorption spectroscopy in conjunction with X-ray crystallography on beamline BM07-FIP2 at the ESRF to compare the structural effects of specific radiation damage o...

We used on-line in crystallo UV–Vis absorption spectroscopy in conjunction with X-ray crystallography on beamline BM07-FIP2 at the ESRF to compare the structural effects of specific radiation damage on two different metal-containing proteins at either room or cryogenic temperature.

The microbial metabolite p-cresol and p-cresol sulfate accumulate in brainstem and inhibit TH and DBH, key enzymes in catecholamine synthesis. This disruption alters brain function and behavior, ...

Les cryptochromes, protéines sensibles à la lumière bleue, règlent notre horloge biologique et pourraient aussi servir de boussole interne aux oiseaux m

Structural analysis of the co-crystal between human DNA glycosylase hOGG1 and a light-sensitive substrate analog highlights its utility as a platform for real-time observation of catalytic dynamics.

Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.

Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.

Spectroscopy, structural, and functional study of microbial rhodopsins with characteristic long-living near–UV-absorbing state.

The rise of time-resolved macromolecular crystallography has been accompanied by renewed interest in companion biophysical characterization methods applicable to molecules both in solution and in crys...

Bacteria aptly use fundamental mechanisms for light-driven proton transfer across a membrane.

Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.

Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.