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山元淳平/Junpei Yamamoto

@junpeiyamamoto.bsky.social
8 followers 10 following 8 posts

Associate Professor in Graduate School of Engineering Science, Osaka University, Japan. Expertise: Nucleic Acids Chemistry, Photobiology, Structural biology. Am always trying to conduct research that only I can do.

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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 03/09/2025
Our collaborative work has been published in Communications Chemistry. Congrats to the co-authors! www.nature.com/articles/s42...
nature.com
Infrared and ultraviolet spectroscopic characterization of a key intermediate during DNA repair by (6-4) photolyase - Communications Chemistry
(6-4) photolyases repair carcinogenic pyrimidine(6-4)pyrimidone photoproducts, a process that requires two successive photons but whose mechanistic details remain elusive. Here, the authors use time-r...
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Reposted by 山元淳平/Junpei Yamamoto
IUCrJ @iucrj.iucr.org · 15/07/2025
Tomoki Imura et al.: Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? #DNARepair #PhotocagedSubstrateAnaloga #HOgg1 @osaka_univ_e...#IUCr journals.iucr.org/paper?S2052252525…
journals.iucr.org
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 15/07/2025
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target? doi.org/10.1107/S205...
doi.org
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Engineered in crystallo photosensitivity in a DNA-repair enzyme is carefully assessed for its suitability as a target for time-resolved crystallographic studies.
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 19/06/2025
On the Thames
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 16/05/2025
Congrats for publication!🥳🎉Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography | Science Advances www.science.org/doi/10.1126/...
science.org
Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Time-resolved crystallography unveils how light-driven chromophore reduction sparks dramatic structural change in a photoreceptor.
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 24/12/2024
Found that the smell of sterilized LB medium filled the hallway, so I checked the autoclave, but nothing wrong with it. When I took off my mask😷, the smell in the hallway disappeared. That means…🧐
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 19/11/2024
Fingerprint-targeting enrichment enabled us to capture new candidate proteins that bind non- canonical i-motif DNA structure. Published in Nucleic Acids Research! doi.org/10.1093/nar/...
doi.org
Profiling of i-motif-binding proteins reveals functional roles of nucleolin in regulation of high-order DNA structures
Abstract. Non-canonical DNA structures, such as the G-quadruplex (G4) and i-motif (iM), are formed at guanine- and cytosine-rich sequences, respectively, i
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 23/10/2024
台湾大学化学科のManuel Maestre-Reyna博士のラボに一週間ほどお世話になるため、台湾に来ました。何とか次の論文を完成させたい!
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山元淳平/Junpei Yamamoto @junpeiyamamoto.bsky.social · 21/10/2024
東北大学際研•佐藤伸一准教授との共同研究がNucleic Acids Research誌に採択されました!JST創発をきっかけに同年代が知り合い意気投合し、お互いの得意分野を活かしたいい仕事が出来て大変満足です😊
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