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Nancy Santiappillai

@nancyts.bsky.social
81 followers 125 following 2 posts

Postdoc fellow in the Keshari lab @MSKCC interested in cancer metabolism, mass spec, imaging, and therapeutics. 🇳🇿 -> 🇦🇺-> 🇺🇸🗽

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Nancy Santiappillai @nancyts.bsky.social · 20/02/2026
Late to post, but so greatful to have presented my talk on prostate cancer metabolism at the @ismrm.bsky.social workshop on Metabolomics and Metabolomic Imaging in Medicine in Padua, Italy! And to be awarded Top Abstract!
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Reposted by Nancy Santiappillai
Molecular Systems Biology @molsystbiol.org · 03/07/2025
reactant and product metabolite ratios revealed metabolic pathways differences between cancer subtypes and noncancer cell lines by @hoylipidlab.bsky.social @sydneyprecisionds.bsky.social @nancyts.bsky.social ➡️ www.embopress.org/doi/full/10....
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Reposted by Nancy Santiappillai
Hoy Lipid Metabolism Lab @hoylipidlab.bsky.social · 06/06/2025
Incredibly proud of our latest publication in @molsystbiol.org led by @nancyts.bsky.social in collab w/ Jean Yang and Lake-Ee Quek - www.embopress.org/doi/full/10.... We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.
embopress.org
Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells | Molecular Systems Biology
imageimagePathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective standard conditions reveals common and distinctive metabolic signatur...
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Nancy Santiappillai @nancyts.bsky.social · 08/04/2025
Had a great time sharing our work on macrophage TNBC symbiosis at the NYAS Cancer and Metabolism symposium!
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Reposted by Nancy Santiappillai
Nature Reviews Cancer @natrevcancer.nature.com · 01/04/2025
In @cp-cancercell.bsky.social, Schild et al. @mskcancercenter.bsky.social engineered T cells & CAR T cells to express the fructose-specific transporter GLUT5, improving T cell glycolytic flux & thus effector function in glucose-limited conditions. 📖 the #researchhighlight 👇
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Sweet success in CAR T cells - Nature Reviews Cancer
Glycolysis-dependent T cell function is hindered by glucose scarcity in the tumour microenvironment. Now in Cancer Cell, Schild et al. engineered T cells to utilize fructose via GLUT5, enhancing their metabolic activity and cytotoxicity.
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