Padvitski, Unger Avila, Chen et al. introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury,...

Padvitski, Unger Avila, Chen et al. introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury,...

The authors use a Caenorhabditis elegans model of Verheij syndrome, caused by mutations in the splicing factor PUF60, and show that Vitamin B12 can rescue the phenotype.

Conducting innovative research in line with the above-mentioned project. Collecting, analyzing, and interpreting data using various OMICs techniques. Conducting in vitro and in vivo experiments. Colla...

npj Aging - An in-depth analysis of the molecular changes induced by short-term calorie restriction before living kidney donation

Oxford Academic

Real-life medical data usage is currently limited by lack of structured databases and analysis tools. Autosomal dominant polycystic kidney disease (ADPKD) remains the most common monogenic cause of ki...

AbstractBackground. Up to 8% of renal tumors have a monogenic cause, yet hereditary renal cell carcinoma (hRCC) syndromes such as Von Hippel–Lindau (VHL),

Abstract. The 2025 KDIGO Clinical Practice Guideline for Autosomal Dominant Polycystic Kidney Disease (ADPKD) addresses intracranial aneurysms (ICAs) and o