Reposted by MoonDeLaAxel
And IN CASE YOU MISSED IT. More recently, two more studies showed updated COVID booster vaccines continue to provide meaningful protection against major adverse outcomes, cardiovascular complications, hospitalization, AND all-cause death.
• www.cidrap.umn.edu/covid-19/upd...
![Results
A total of 22767 546 vaccinated and 5932 443
unvaccinated individuals were followed up for a median
(IQR) of 45(44-46) months. Vaccinated individuals were older than unvaccinated individuals (mean [SD] age, 38.0 [11.8] years vs 37.1 [11.4] years), more frequently women (11688 603[51.3%] vs 2 876 039 [48.5%]) and had more cardiometabolic comorbidities (2126 250[9.3%] vs 464 596[7.8%]). During follow-up, 98 429(0.4%) and 32662 (0.6%) all-cause deaths occurred in the vaccinated and unvaccinated groups, respectively. Vaccinated individuals had a 74% lower risk of death from severe COVID-19 (weighted hazard ratio [WHR], 0.26 [95% CI, 0.22-0.30]) and a 25% lower risk of all-cause mortality (wHR, 0.75 [95% CI, 0.75-0.76]), with a similar association observed when excluding severe COVID-19 death. Sensitivity analysis revealed that vaccinated individuals consistently had a lower risk of death, regardless of the cause. Mortality was 29% lower within 6 months following COVID-19 vaccination (relative incidence, 0.71 [95% CI,
0.69-0.73]).
Conclusions and Relevance
In this national cohort study of 28 million individuals, the results found no increased risk of 4-year all-cause mortality in individuals aged 18 to 59 years vaccinated against COVID-19, further supporting the safety of the mRNA vaccines that are widely used worldwide.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:llgfbjvsqkaicezsf7mzjxr3/bafkreiaetadcmwtuqyko4zil4s77bt27sisq2pchm3sdessphb6wwuu6me)
