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Manjari Anant

@mmganant.bsky.social
30 followers 63 following 2 posts

Neuroscience PhD Student in the JEFworks and Kebschull labs @JohnsHopkins

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Reposted by Manjari Anant
Cedric Boeckx @cedricboeckx.bsky.social · 20/09/2026
Excellent preprint from @justuskebschull.bsky.social’s lab showing how new cerebellar nuclei arise by excitatory progenitor diversification in the early rhombic lip 🧪🧠🧬 www.biorxiv.org/content/10.6...
biorxiv.org
Evolution of new cerebellar nuclei by excitatory progenitor diversification in the early rhombic lip
The cerebellar nuclei, the output regions of the cerebellum, have evolved via repeated duplication of a conserved cell type set to produce different numbers of nuclei across species. Here, we investig...
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Manjari Anant @mmganant.bsky.social · 22/09/2026
Really excited to share this work with the community! Big thanks to @justuskebschull.bsky.social and @jef.works, as well as our lab members and collaborators, for their support and fun discussions throughout this project!
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Reposted by Manjari Anant
Tetsuya Yamada @tyamadat.bsky.social · 30/07/2026
Our manuscript on the co-option of TEs as cerebellar CREs is now officially published in @natcomms.nature.com! Huge thanks to @kaessmannlab.bsky.social @marisepp.bsky.social, and @ioansarr.bsky.social for the fantastic collaboration throughout this project! www.nature.com/articles/s41...
nature.com
Gene regulatory innovations from transposable elements in primate cerebellum development - Nature Communications
The roles of transposable elements in primate brain development remain underexplored. Here, the authors identify transposable elements with ancestral regulatory potential that have been co-opted as ci...
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Reposted by Manjari Anant
Lena Kutscher @lenakutscher.bsky.social · 01/08/2026
New preprint from the lab! Led by PhD students @vuslatakcay.bsky.social, Lisa Spänig and Wouter-Michiel Vierdag (EMBL), we investigated the development and differentiation of cerebellar unipolar brush cell progenitors (UBCPs). www.biorxiv.org/content/10.6...
biorxiv.org
Conserved cerebellar rhombic lip compartmentalization and Eomes regulatory networks govern unipolar brush cell development
The rhombic lip (RL) gives rise to all cerebellar glutamatergic cell types, including unipolar brush cells (UBCs). Disruptions to UBC development can lead to the neurodevelopmental disorder Dandy-Walk...
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Reposted by Manjari Anant
Justus Kebschull @justuskebschull.bsky.social · 17/05/2026
New from the lab: BARseq3! Barcodes + high efficiency spatial transcriptomics and translatomics in the same cells, or just a nice spatial transcriptomics assay. All in a modular, expandable system to enable truly multimodal measurements. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Manjari Anant
Journal of Open Source Software @joss-openjournals.bsky.social · 14/01/2026
Just published in JOSS: 'DART: A GUI Pipeline for Aligning Histological Brain Sections to 3D Atlases and Automating Laser Microdissection' doi.org/10.21105/joss.09109
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Reposted by Manjari Anant
Justus Kebschull @justuskebschull.bsky.social · 09/09/2025
Annoyed at how difficult MAPseq dissections can be? Check out the new preprint from Kebschull undergrad Rishi Koneru and grad student @mmganant.bsky.social: www.biorxiv.org/content/10.1...
biorxiv.org
DART: A GUI Pipeline for Aligning Histological Brain Sections to 3D Atlases and Automating Laser Microdissection
The precise dissection of anatomically defined brain regions is the basis of many workflows in neurobiology. Traditionally, brain regions of interest are defined by visual inspection of tissue section...
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Reposted by Manjari Anant
Justus Kebschull @justuskebschull.bsky.social · 26/06/2025
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.
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