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Like many other bacterial organisms, Xanthomonas campestris pv. campestris (Xcc) employs two motility appendages, a single polar flagellum and type IV pili, for sensing environmental cues and travers...

Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (Plp...

Coxiella burnetii modulates a variety of host cell processes to create a niche permissive for its intracellular replication using effectors injected by its Dot/Icm type IV secretion system. More than...

Pseudomonas aeruginosa is a significant opportunistic pathogen, particularly prevalent in intensive care units (ICUs). Through a comprehensive genomic and phenotypic analysis of 518 ICU and healthy i...

Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ-herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Exp...

Occult HBV infection (OBI) is characterized by the presence of replication-competent hepatitis B virus (HBV) DNA (covalently closed circular DNA [cccDNA] and/or relaxed circular DNA [rcDNA]) in the l...

Pseudomonas aeruginosa is a major nosocomial pathogen in which the type VI secretion system (T6SS) contributes to interbacterial competition and virulence. While most strains encode three T6SSs, addi...

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The reduction of iodate by Shewanella species plays a crucial role in iodine biogeochemical cycling. However, the physiological significance of this reduction process remains poorly understood, becau...

Ecosystem retrogression drives nutrient depletion, reduced productivity, and profound reorganization of soil microbial communities. Using amplicon sequencing and genome-resolved metagenomics, we exam...

Like many other bacterial organisms, Xanthomonas campestris pv. campestris (Xcc) employs two motility appendages, a single polar flagellum and type IV pili, for sensing environmental cues and travers...

Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (Plp...

Coxiella burnetii modulates a variety of host cell processes to create a niche permissive for its intracellular replication using effectors injected by its Dot/Icm type IV secretion system. More than...

Epstein–Barr virus (EBV), the first identified human oncovirus, is a ubiquitous γ-herpesvirus etiologically linked to diverse malignancies, lymphoproliferative disorders, and autoimmune diseases. Exp...

Occult HBV infection (OBI) is characterized by the presence of replication-competent hepatitis B virus (HBV) DNA (covalently closed circular DNA [cccDNA] and/or relaxed circular DNA [rcDNA]) in the l...

Koch et al. propose replacing “synthetic microbial communities (SynComs)” with “defined microbial communities”. We argue that this substitution obscures the design-driven logic of SynCom research, and...

Abstract. Microorganisms assemble into spatially structured communities in which neighboring cells are separated by highly heterogeneous cell-cell distance

Laboratory of microbial trophic interactions and host-microbe associations