iiinova — where your digital self keeps evolving

Reposted by Michelle Huang

Heilshorn Lab @heilshornlab.bsky.social · 09/04/2025

We are thrilled to be at #SFB2025 in Chicago this week! @vanessadoulames.bsky.social will be sharing some of our recent work on a hydrogel-mediated approach for spinal cord injury. Excited to see everyone! 🤗

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Reposted by Michelle Huang

Prasad Jallepalli, MD, PhD @prasad.bsky.social · 04/04/2025

www.nytimes.com/2025/04/03/o... Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security

nytimes.com

Opinion | The Uncertain Fate of the Young American Scientist (Gift Article)

Young researchers are choosing between staying in science and staying in the United States.

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Reposted by Michelle Huang

Prof. Brian Aguado @brianaguado.bsky.social · 19/02/2025

My statement regarding the decision to drop the second round of the CZI Science Diversity Leadership Award funding opportunity:

I am crushed that the Chan Zuckerberg Initiative has decided not to continue with the second round of the Science Diversity Leadership Awards. My heart breaks for all the scientists that submitted their grant applications with the hope that their research and community building ideas would be funded to help make the science world a more equitable place. I see you. Please take the time to mourn the loss of your time and effort and figure out your next move.

I feel an intense surge of survivors’ guilt. As part of the first (and now last) CZI SDL cohort, I have enjoyed significant personal and professional opportunities that have emerged after receiving the award – opportunities that have now vanished for future science diversity leaders. The award gave me confidence in my research program, but more importantly, was the catalyst I needed to bring my full self to the laboratory. After receiving the CZI award, I finally felt comfortable fully coming out to the scientific community and embracing my identity as a proud queer Latino scientist. The award was extremely unique and enabling, allowing me to build a vibrant laboratory community, support various professional development activities for trainees, and grow my research program focused on understanding sex differences in biology towards our goal of health equity. I am devastated that future scientists with stories like mine will not have the financial support they need to achieve their vision in promoting diversity, equity, and inclusion.

As a Science Diversity Leader, I remain fiercely committed to my personal and professional mission to promote diversity through impactful science and community building efforts. I will continue using this platform to uplift diverse voices in the scientific community. To those feeling hopeless, please know that our continued commitment and presence in science is a powerful form of social justice. Let us continue using our creative minds and resources to fight inequities in society - …

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Reposted by Michelle Huang

Heilshorn Lab @heilshornlab.bsky.social · 19/01/2025

A bittersweet goodbye to Dr. David Kilian as we send him off to the Netherlands! David will be joining the MERLN Institute at Maastricht University to start his independent research group! 🥳 We wish him the best and of course will miss him so much 🥺🫶

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Reposted by Michelle Huang

Heilshorn Lab @heilshornlab.bsky.social · 14/01/2025

📣 Excited to share our first manuscript of 2025 where we present an interpenetrating network of physically assembled collagen and covalently-crosslinked collagen, which contains *both* fibrous and amorphous #collagen networks! Led by @luciabru.bsky.social & @chrislong42.bsky.social, check it out!

sciencedirect.com

Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability

Hydrogels composed of collagen, the most abundant protein in the human body, are widely used as scaffolds for tissue engineering due to their ability …

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Reposted by Michelle Huang

Heilshorn Lab @heilshornlab.bsky.social · 18/12/2024

Happy holidays from the Heilshorn Lab! Great way to end the year celebrating each other’s accomplishments together 🤗🎄☃️

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Michelle Huang @michshuang.bsky.social · 16/12/2024

Excited to share our new review on #organoid #bioprinting in Nature Reviews Bioengineering! 🎉 @natureportfolio.bsky.social We highlight recent advances and envision a future that integrates organoid biology and biofabrication approaches to engineer complex tissues. Hope you enjoy! 🔓: rdcu.be/d3H6u

rdcu.be

Organoid bioprinting: from cells to functional tissues

Nature Reviews Bioengineering - Integrating bioprinting with organoid technology can enhance tissue engineering by improving complexity, reproducibility and scalability. This Review discusses...

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Reposted by Michelle Huang

Danielle J. Mai @daniellejmai.bsky.social · 24/11/2024

1st post in a new space seems like a good spot to feature the 1st project by the lab's 1st PhD student! We set out to engineer calcium-responsive proteins as muscle-mimetic materials and discovered some surprises along the way. Congrats to Marina, Winnie, Gatha, and Kenny! doi.org/10.1039/D4PY...

doi.org

Sequence-defined structural transitions by calcium-responsive proteins

Biopolymer sequences dictate their functions, and protein-based polymers are a promising platform to establish sequence–function relationships for novel biopolymers. To efficiently explore vast sequen...

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Reposted by Michelle Huang

Heilshorn Lab @heilshornlab.bsky.social · 22/11/2024

Hi 🦋! We are a biomaterials group at Stanford interested in tissue engineering, biofabrication, and hydrogel-based therapies. And we just celebrated labsgiving! 🤗🦃 #HiSky #SciSky

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Reposted by Michelle Huang

Garrett Beeghly, PhD @gbeeghly.bsky.social · 18/11/2024

I didn’t see a general starter pack for people in the #BME and #BioE communities so I started to put one together. Let me know if I’ve missed anyone in particular or if you’d like to be added! #ScienceSky #AcademicSky go.bsky.app/9nMCGLK

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Reposted by Michelle Huang

Kumar Lab, UC Berkeley @kumarlabucb.bsky.social · 18/11/2024

New paper in Advanced Materials! We develop a family of 3D viscoelastic HA matrices and use them to study effects of stress relaxation on GBM invasion. Led by ChemE PhD student Emily Carvalho in collaboration with Andreas Stahl (UCB) and Manish Aghi (UCSF) onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Viscoelastic High‐Molecular‐Weight Hyaluronic Acid Hydrogels Support Rapid Glioblastoma Cell Invasion with Leader–Follower Dynamics

Glioblastoma spheroids invade faster in stress-relaxing, high-molecular-weight (HMW) hyaluronic acid hydrogels than in more elastic-like, low-molecular-weight counterparts. The long HMW chains create....

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Reposted by Michelle Huang

Woojin Han @thewooj.bsky.social · 11/11/2024

Here’s our latest research! How do 3D mechanical cues shape muscle stem cells (MuSCs) in regeneration? We took a deep dive into this question in our latest work: www.biorxiv.org/content/10.1...

biorxiv.org

3D mechanical confinement directs muscle stem cell fate and function

Muscle stem cells (MuSCs) play a crucial role in skeletal muscle regeneration, residing in a niche that undergoes dimensional and mechanical changes throughout the regeneration process. This study inv...

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