iiinova — where your digital self keeps evolving

Michele Gabriele @michelegabriele.bsky.social · 20/05/2026

Thrilled to welcome @jpflores.rbind.io to the lab as a Fulbright U.S. Scholar! 🎉🇮🇹 JP will be joining us at SR-Tiget in Milan to dig deep into 3D genome dynamics and enhancer biology! Couldn't think of a better addition to the team. Fulbright + great science + Milan. See you soon, JP! 🧬

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Michele Gabriele @michelegabriele.bsky.social · 15/01/2026

With a bit of a delay, I’m very excited to welcome Anna Cavagnoli, the first PhD student of Gabriele Lab! lnkd.in/ddY5Y-bz 🎉🎉🎉 Anna is enrolled in the very first cycle of the Science and Technology for Advanced Therapies PhD program at the Scuola Universitaria Superiore Pavia!

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Michele Gabriele @michelegabriele.bsky.social · 19/09/2025

Welcome to Sabrina Savoia and Ilaria Locatelli, the first members of the lab! We are officially operative! 🥳 gabrielelab.com/team

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Michele Gabriele @michelegabriele.bsky.social · 18/07/2025

At SR-Tiget we are seeking outstanding mid-career scientists in Computational biology, AI, and Molecular immunology who wish to translate their results into therapeutic advances with a focus on genetic diseases! Deadline 1st September 2025! www.linkedin.com/posts/sr-tig...

linkedin.com

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Michele Gabriele @michelegabriele.bsky.social · 23/06/2025

Are you a mid-career group leader in computational bio/AI/molecular immunology who wants to move the lab to Italy? (preferentially from USA?) The SR-TIGET (Milan, Italy) is recruiting someone like you! Here the call: back.fondazionetelethon.it/uploads/2025...

back.fondazionetelethon.it

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Michele Gabriele @michelegabriele.bsky.social · 23/06/2025

Have you recently finished your PhD and had excellent productivity? Telethon foundation is starting a postdoctoral program with a competetive 3-years fully funded position! Send CV and PI preference (included me, I am not yet in the website) details here: back.fondazionetelethon.it/uploads/2025...

back.fondazionetelethon.it

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Reposted by Michele Gabriele

matteomazzocca.bsky.social @matteomazzocca.bsky.social · 14/05/2025

3/ We ran simulations to estimate EP search times based on 1) measured subdiffusion, 2) physical/genomic distance. Within 300nm (~<200 kb), a gene can find 1000s of enhancers in minutes. Such encounters can’t be selective → EP selectivity needs other mechanisms, e.g. biochemical

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Michele Gabriele @michelegabriele.bsky.social · 15/05/2025

This new preprint from my labmates provides a new perspective on chromatin dynamics! Strongly suggested to everyone into chromatin given its broad impact!

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Reposted by Michele Gabriele

Ludovico Rizzuti @ludoritz.bsky.social · 03/04/2025

I'm happy to share our work on the neurodevelopmental impact of ADNP mutations in ASD and beyond. It has been an exciting ride to share with @alessandrovitriolo.bsky.social, Mariana, and the people of the Testa and Poot Labs. Full paper here: www.biorxiv.org/content/10.1... Thread below 🧵

biorxiv.org

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Michele Gabriele @michelegabriele.bsky.social · 24/02/2025

I'm proud to share that our modeling of #YY1 haploinsufficiency has just been published! www.nature.com/articles/s41... Using #organoids and #neurons we discovered that YY1 mutations affect the cross-talk between cells and also cause a non-cell autonomous phenotype in a cell-type specific manner.

nature.com

Article Metrics - YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs | Molecular Psychiatry

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Michele Gabriele @michelegabriele.bsky.social · 19/01/2025

Starting 2025 with a genome architecture paper about absolute quantification of looped states, lead by James Jusuf!

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