Reposted by Merve YigitSendoel Lab @sendoellab.bsky.social · 22/05/2026Very happy to see our study on the development of an in vivo single-cell ribosome profiling strategy for the epidermis now online at @cp-molcell.bsky.social. Fantastic work by @claradure.bsky.social and all co-authors involved. www.cell.com/molecular-ce...cell.comIn vivo single-cell ribosome profiling reveals cell-type-specific translational programs during agingIn vivo single-cell ribosome profiling reveals cell-type-specific translational landscapes across the epidermis and uncovers selective reprogramming of AP-1 subunit translation in aged stem cells, lin... 1239
Merve Yigit @merveyigit.bsky.social · 26/07/2025Check out the latest work from our lab! Amazing job @dadita.bsky.social 👏🏻👏🏻💯 010
Merve Yigit @merveyigit.bsky.social · 29/06/2025PhDone 🥳🎓 The last few years was full of successes, failures, ups and downs, but also full of amazing people, countless talks, great conferences, incredible science and endless support from my supervisor and my thesis committee. Thanks to all people who helped me in this amazing journey! #eIF2A 061
Merve Yigit @merveyigit.bsky.social · 29/06/2025Thank you! It was an incredible journey. Many thanks to all my committee members, great collaborations and amazing supervision! 000
Reposted by Merve YigitSIRD - Swiss Initiative for RNA & Disease @swissinitiativerna.bsky.social · 27/05/2025Preprint by the Sendoel Lab ( @sendoellab.bsky.social ) with first author Merve Yigit ( @merveyigit.bsky.social "The alternative initiation factor eIF2A regulates 40S subunit turnover in ribosome-associated quality control" @biorxivpreprint.bsky.social buff.ly/hP9Iani @anupamd.bsky.social 042
Merve Yigit @merveyigit.bsky.social · 26/05/2025#alternativetranslation #cancer #scc #ribosomequalitycontrol #ribosome #skin #usp10 #g3bp1 #rnf10 #ubiquitin #turboID #silac #massspectrometry #proteomics #riboseq #eIF2A #translation #mRNA 010
Merve Yigit @merveyigit.bsky.social · 26/05/2025I’m thrilled to share my very first first-author preprint and our lab’s latest work💫 We discovered a novel role for eIF2A in ribosome-associated quality control (RQC), challenging decades-old assumptions about its enigmatic function in translation initiation. Check it out to learn more! ⭐️ #RNA 1438
Merve Yigit @merveyigit.bsky.social · 12/12/2024Oh, the weather outside is frightful But the paper submission is so delightful And since we've no results yet Let it pipette, let it pipette, let it pipette 060
Reposted by Merve YigitSendoel Lab @sendoellab.bsky.social · 18/11/2024How does aging alter the translational landscape of stem cells and how do these changes impact their regenerative capacity? Here we developed an in vivo single-cell ribosome profiling strategy to monitor translational landscapes of the mouse epidermis 1/6 www.biorxiv.org/content/10.1... 1195
