AbstractMpox is a zoonotic disease caused by the monkeypox virus (MPXV). Historically, mpox was endemic to Central and West Africa, but since May 2022, the number of mpox cases has increased with the

AbstractSnakebite is a medical emergency causing rapid onset of both local tissue-destructive and potentially lethal systemic haemorrhagic and neurotoxic pathologies. Snakebite primarily afflicts

AbstractMany monoclonal antibodies (mAbs) licensed today are so-called ‘blockbuster’ therapies, with the majority of the Top 10 best-selling therapeutic drugs being mAbs. Until recently, mAbs for

A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkha...

In Brazil, a group of researchers from the Federal University of São Paulo (UNIFESP) and the Butantan Institute have developed a new version of the antibothropic serum that is three times more effective than the version currently used to treat envenomation by snakes of the genus Bothrops, the jararaca (B.

Snakebite envenoming is a neglected tropical disease that affects millions globally each year. In recent years, research into the potential production of recombinant antivenoms, formulated using mi...

Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...