iiinova — where your digital self keeps evolving

Reposted by Jan Remsik 🌺🌈💊

Siegenthaler Lab @siegenthalerlab.bsky.social · 06/03/2026

🚨 New preprint from our lab led by Sophia Kim w/ @kellydoran.bsky.social group @cuanschutz.bsky.social -- using neonatal 🐭 model of bacterial meningitis ➡️ arachnoid barrier is leaky, Cldn11 junctions are disrupted & cytokines are part of the problem. Lots of 🤩🧠🦠🔬 & compelling data, check it out! 1/5

graphical schematic of the meninges on top depicting the three layers [dura, arachnoid and pia] and other immune and vascular cell types. Inset shows Claudin-11 junction proteins connecting two sides of arachnoid barrier cells

bottom schematic is the same but in inflammation with bacteria, junctions breakdown, depiction of cytokine release by vascular, meningeal and immune cells - at side of graphic is summary of defects we observe in infection: 'increased barrier permeability' 'mislocalization of Cldn11+ tight junction' 'BAM activation' and "increased inflammatory response'

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Reposted by Jan Remsik 🌺🌈💊

Leon Smyth @leonsmyth.bsky.social · 07/01/2026

WE ARE HIRING! The Smyth Lab at Monash University is looking for a postdoc to join our team! Come join us if you are excited about neuroimmunology and the meninges. 📍 Melbourne, Australia 🇦🇺 Apply now: careers.pageuppeople.com/513/cw/en/jo... #Neuroimmunology #Meninges #PostdocJobs

careers.pageuppeople.com

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NEJM.org @nejm.org · 21/12/2025

HPV vaccination could prevent most cervical cancers, but only 27% of eligible adolescent girls worldwide have received the vaccine. Data suggest that a single dose may be protective. Research findings from the ESCUDDO trial are summarized in a new Quick Take video. nej.md/3MFcHBr #MedSky #IDSky

A visual representation of the ESCUDDO trial, which examined whether a single dose of HPV vaccination could help to protect adolescent girls against most cervical cancers.

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Reposted by Jan Remsik 🌺🌈💊

valientelab.bsky.social @valientelab.bsky.social · 04/12/2025

Volume II of The Evolving Landscape of Brain Metastasis: 17 leading figures in the field looked back and identified the most relevant discoveries since volume I, 8 years ago. The landscape is starting to look better, but still lots of things to do! www.cell.com/trends/cance...

cell.com

The evolving landscape of brain metastasis: volume II

Brain metastasis (BrM) represents the most common intracranial malignancy, arising in up to 30% of all adult cancer patients and contributing significantly to cancer-related morbidity and mortality. B...

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Reposted by Jan Remsik 🌺🌈💊

Fendt Lab @fendtlab.bsky.social · 05/09/2025

Come join us for your next research endeavor in the heart of Europe!

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Reposted by Jan Remsik 🌺🌈💊

danapeer.bsky.social @danapeer.bsky.social · 14/05/2025

I am pleased to share our recent publication, fruit of a wonderful collaboration with truly amazing colleagues @adrienneboire.bsky.social and @meningojan.bsky.social, whose work was a tour de force demonstrating that immunology in the brain is a different beast -> www.nature.com/articles/s41...

nature.com

Interferon-γ orchestrates leptomeningeal anti-tumour response - Nature

Independent of antigen presentation, migratory CCR7+ dendritic cells orchestrate the influx, proliferation and cytotoxic action of natural killer cells to control cancer cell growth in the leptomening...

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Reposted by Jan Remsik 🌺🌈💊

Adrienne Boire @adrienneboire.bsky.social · 14/05/2025

I am delighted to share that our work focused on anti-tumor immunity in the leptomeningeal space was published today: www.nature.com/articles/s41... @meningojan.bsky.social

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Reposted by Jan Remsik 🌺🌈💊

yEFIS @yefis-immunology.bsky.social · 12/05/2025

Join us on May 27 at 3pm CEST for an inspiring talk with Isabel Torres CEO of Mothers in Science, on how parenthood impacts careers in STEMM & Q&A👩‍🔬👨‍👧‍👦 📍Does parenthood impact career progression in STEMM? Organized by the #yEFIS Improving Academia Working Group Register: tinyurl.com/yefis2025-ia1

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 23/01/2025

As the Trump Administration destroys the institutional progress we have made in diversity, equity and inclusion in science & education, each of us retains the opportunity to reflect and speak out. The piece I wrote four years ago is even more relevant today 🧪 www.molbiolcell.org/doi/10.1091/...

Looking back on a life of unacknowledged privilege and a call to action
The year 2020 provided a wake-up call about the role systemic racism plays in shaping our nation and shaping science. While hard work and great mentors helped bring me a long way from a farm in Minnesota, it’s become much clearer that the privilege of being white and male and the accumulated advantages that began there played powerful roles. It’s time for white scientists like me to listen, think, and take action.

We all have personal stories that we use to describe our trajectory in life and science. For the past five decades the narrative I told myself was a simple one of good luck, hard work, support from my community, and mentors at pivotal times. However, in many important ways, this was just a small part of the truth, ignoring the role unperceived privilege played. The many underlying injustices that were laid bare in our nation this past year began to open my eyes, prompting me to look back at the roles hidden privilege played in my career and the power that these have given me. This challenged me to use the power of that privilege to speak and act to try to change the system in which engrained advantages benefit some but not all. I am telling my story in hopes it will encourage my white colleagues to examine their own.

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Chris Marine Lab @marinelab.bsky.social · 17/12/2024

Looking for an enthusiastic bioinformatician (long-term postdoctoral follow or staff scientist) interested in cancer/melanoma biology and therapy resistance. Data Science (single-cell, spatial multiomics integration), Machine learning, R, Pyhthon... jobso.id/ik9e

jobso.id

Bioinformatician Postdoctoral Level - VIB

Position summary The Chris Marine lab at the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) is actively seeking a skilled bioinformatician proficient in analyzing and integrating single-...

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