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Matt Hufford

@mbhufford.bsky.social
357 followers 151 following 22 posts

Evolutionary Genomicist, EEOB Dept., Iowa State University, evolution of maize and its wild relatives

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Matt Hufford @mbhufford.bsky.social · 03/03/2026
Corrinne Grover and I are hiring a postdoc to work on population and comparative genomics in multiple crop species. Applications will be accepted through March 17th and details can be found here: isu.wd1.myworkdayjobs.com/IowaStateJob...
isu.wd1.myworkdayjobs.com
Postdoctoral Researcher - Evolutionary Genomics and Population Genetics
Position Title: Postdoctoral Researcher - Evolutionary Genomics and Population Genetics Appointment Type: Post Doc/Trainee Job Description: Summary of Duties and Responsibilities: We are seeking a Pos...
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Charlie Hale @charleshale.bsky.social · 16/12/2025
Our paper is out in MBE! doi.org/10.1093/molb... We tracked TF binding site evolution across 589 grass species, and found that while binding preferences are pretty stable over 80 million years of evolution, individual binding sites have turned over a lot. Thread here: bsky.app/profile/char...
Grasses share a conserved set of cis-regulatory motifs, but individual motif instances have turned over repeatedly across 80 million years of evolution.
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Matt Hufford @mbhufford.bsky.social · 14/07/2025
Exciting news from NSF today! Our proposal to host an EPSCoR Graduate Training Program at ISU in the biological sciences has been funded. Students receiving an honorable mention in the GRFP competition are eligible. We have a diverse set of faculty participating across the breadth of biology.
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MaggieBeth @maggiebeth.space · 08/04/2025
According to the posted lists for this year, only 1,000 applicants received the GRFP and ~ 3,000 were named honorable mentions. The solicitation stated there would be 2,300 awards, so this is a massive cut. 🧪🔭
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Dr. David Miller 🏳️‍🌈 @davidimiller.bsky.social · 08/04/2025
🚨 Not a drill: NSF GRFP results are NOW OUT!!!!! But...good news and bad news. 👍 I'm *thrilled* for the grad students for whom getting this award will be life-changing, esp now. 👎 # of fellowships went down by 51% (1000 this year vs. 2036 last year) See here: www.research.gov/grfp/Awardee...
research.gov
Research.gov :: GRFP
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 10/02/2025
In our latest @biorxiv-genomic.bsky.social preprint, we describe our approach to use PacBio HiFi reads to detect somatic TE transposition -- good enough to detect rare events that are present in only single cells. Led by Andrea Movilli. #plantscience www.biorxiv.org/content/10.1...
Diagram of somatic TE insertions across the A. thaliana genome
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Vaughn Cooper @vscooper.micropopbio.org · 10/02/2025
Many people, including academics, don't understand what F&A is for. Please share to help. 1) Translate to "overhead" in common business accounting: 60% IDC => 60/160 = 37.5% overhead (low!) 2) Infographic explaining what it's for, linked here: www.cogr.edu/sites/defaul...
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Mary Williams @PlantTeaching @plantteaching.bsky.social · 30/01/2025
Is anyone going to the AAAS meeting in Boston in February? I would love a recap of this panel discussion! (Or even better, livestream? Would that be possible AAAS? "Sustaining Inclusion Work in Challenging Political & Legal Environments"
1:00 PM: Sustaining Inclusion Work in Challenging Political & Legal Environments
Registration type: Basic, Deluxe
In this session, we will offer several different perspectives about the current environment, looking back on historical context, examining the legal context of what we can do, and, by exploring the research, looking at the impacts of current challenges on climate and culture. A moderated discussion will explore how to leverage these contexts and perspectives to sustain the work of inclusion by focusing on transforming our institutional structures and systems.
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Michelle Stitzer @mcstitzer.bsky.social · 27/01/2025
New preprint featuring my favorite maize-relatives, the Andropogoneae! We sequenced the genomes of 27 species, including lemongrass, kangaroo grass, little and big bluestem, and more -- key species that shape grasslands and prairies worldwide. www.biorxiv.org/content/10.1...
On top, five Andropogoneae grass species, from left to right Zea mays subsp. mays, Hemarthria uncinata, Miscanthus sinensis, Sorghum bicolor, Andropogon gerardi. On bottom, a map of the world, with collection sites of Andropogoneae grasses in points. A green background shows the distribution of Andropogoneae grasses throughout tropical and temperate latitudesOn left, a phylogeny of Andropogoneae species, with 14 independent polyploidy origins noted. On right, genome size and repeat content of each assembly. Across all assemblies, average assembly size is 1.9 Gb, and average repeat size is 1.5 Gb.
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 27/01/2025
I totally forgot that in addition to the radical genomics, Michelle put together a website where you can learn about the biology of all the species we looked worked with: mcstitzer.github.io/panand_assem...
mcstitzer.github.io
Panand Genomes
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Matt Hufford @mbhufford.bsky.social · 26/01/2025
The latest preprint from the PanAnd project, led by @mcstitzer.bsky.social is out today. We look at genome evolution in the Andropogoneae tribe of grasses. Interesting to see how processes occurring in #maize after #polyploidy may not be a general phenomenon. www.biorxiv.org/content/10.1...
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Matt Hufford @mbhufford.bsky.social · 26/12/2024
New preprint from @sjsnodgrass.bsky.social and our colleagues showing variable fractionation in Zea and Tripsacum post-polyploidy. We welcome your thoughts as we work toward submission to a journal. www.biorxiv.org/content/10.1...
biorxiv.org
Maize and wild relatives show distinct patterns of genome downsizing following polyploidy
Plant genomes are smaller than expected despite the ubiquity of polyploidy due to the process of genome downsizing called fractionation. This process causes loss of DNA sequences, including genes, unt...
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Matt Hufford @mbhufford.bsky.social · 26/08/2024
First day of class at ISU! As the campus bustles with activity, I'm reminded that a college education is a dream come true and something that students and their families have worked and saved for for years. Hoping to live up to their expectations as I teach this semester!
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Matt Hufford @mbhufford.bsky.social · 12/07/2024
My group is recruiting a bioinformatician for genomic studies in maize. The position includes work on diverse projects and collaborations with the Maize Genetics and Genomics Database, the CERCA project, and others in the Hufford Lab. isu.wd1.myworkdayjobs.com/IowaStateJob...
isu.wd1.myworkdayjobs.com
Research Scientist II
Position Title: Research Scientist II Job Group: Professional & Scientific Required Minimum Qualifications: Bachelor’s degree and 2 years of related experience Preferred Qualifications: PhD in Bio...
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Matt Hufford @mbhufford.bsky.social · 01/04/2024
I am hiring a postdoc to work on evolutionary genomics projects with maize and its wild relatives. This is part of a broad collaborative project known as CERCA that aims to improve maize with adaptations from the wild. Please share or consider applying! isu.wd1.myworkdayjobs.com/IowaStateJob...
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Matt Hufford @mbhufford.bsky.social · 23/01/2024
The Zeavolution webinar on maize evolution will have it's first 2024 meeting tomorrow at 10am CST. Mohamed El Walid (Buckler Lab at Cornell) will get us started! DM me if you need to be added to the Zeavolution Slack, need connection details, or would like to speak in the series!
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Matt Hufford @mbhufford.bsky.social · 15/12/2023
Lovely holiday party with the lab last night, with Yogi the pug also getting into the spirit. So fortunate to work with these brilliant, fun people!
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David Lowry @davidlowry.bsky.social · 08/12/2023
I've been searching for the breakpoints of this adaptive chromosomal inversion for 15 years. We have now finally found those breakpoints and have discovered that the inversion contains an even older large inversion. This and more in this new preprint. www.biorxiv.org/content/10.1...
biorxiv.org
The role of breakpoint mutations, supergene effects, and ancient nested rearrangements in the evolut...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Matt Hufford @mbhufford.bsky.social · 07/12/2023
Inaugural Bluesky post (👋 Everyone!): The Ecology, Evolution, and Organismal Biology Dept. at Iowa State U. (my dept!) is conducting an open search at the rank of Professor for a new Dept. Chair! isu.wd1.myworkdayjobs.com/en-US/IowaSt...
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