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Background Time-to-event data is commonly used in non-inferiority clinical trials. While the hazard ratio is a popular summary measure in this context, the difference in restricted mean survival time ...

Reference-based multiple imputation provides a practical information anchored tool for inferences about the treatment effect for a treatment policy estimand with a longitudinal binary outcome. The latent multivariate normal model is the preferred implementation.

Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thu....

Introduction In clinical trials, a treatment policy strategy is often used to handle treatment nonadherence. However, estimation in this context is complicated when data are missing after treatment .....

PhD Project - Designs for sequences of early phase (modular) studies at University of Cambridge, listed on FindAPhD.com

Over the 25-year history of the MRC Clinical Trials Unit at UCL, our methodology researchers have pioneered several innovative designs to make randomised cli...

PhD Project - Improving Design and Analysis of Non-Inferiority Trials with sparse outcome data at University College London, listed on FindAPhD.com

Aesop, Marginality Principle, Interactions and Children's Books. In the past few months / years I unfortunately found myself reading less and less. There are only two categories of books that I still ...