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martijnrutten.bsky.social

@martijnrutten.bsky.social
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Jolien Rietkerk @jolienrietkerk.bsky.social · 24/07/2025
‘Genetic Risk Effects on Psychiatric Disorders Act in Sets’, the title of our new preprint on @medrxivpreprint.bsky.social! This huge collaborative effort advances our understanding of psychiatric genetic architecture and emphasizes the importance of looking beyond additive effects. 🧵1/n; 🧪👩🏽‍🔬🧬
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Demarialab @demarialab.bsky.social · 26/03/2025
🎉 Congrats on the successful MoHAD Postdoc/Early Researcher Day, organized by postdocs @martijnrutten.bsky.social & @jamilnehme.bsky.social from our lab! An inspiring event with career talks, great presentations, lively discussions, and creative brainstorming to foster collaboration. 🚀
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martijnrutten.bsky.social @martijnrutten.bsky.social · 13/03/2025
Great first Joint Meeting of the UMCG’s three Research Institutes! @umcgroningen.bsky.social #umcgresearch #MoHAD
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The EMBO Journal @embojournal.org · 11/02/2025
CDK4/6 inhibitors transiently induce a senescence-like state in breast cancer cells, which however cannot be eliminated by senolytics - but Marco Demaria, Boshi Wang and coworkers @demarialab.bsky.social find that they are instead sensitive to lysosomotropic agents! www.embopress.org/doi/full/10....
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Demarialab @demarialab.bsky.social · 27/02/2025
🔬 Journal Club Today, our Master’s student Vlaicu presented a fascinating topic: Senescent cells evade NK cells by upregulating GD3—blocking GD3 restores immune clearance, reducing fibrosis and aging damage. 🛡️🔬 #Aging #Senescence #Immunotherapy www-nature-com.proxy-ub.rug.nl/articles/s43...
www-nature-com.proxy-ub.rug.nl
RUG library off-campus access
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Demarialab @demarialab.bsky.social · 14/02/2025
🔬 Journal Club This week, @martijnrutten.bsky.social presented "Exosomal miR-302b rejuvenates aging mice" (Bi et al., Cell Metab, 2025). 🧬 miR-302b rescues proliferative arrest in senescent cells 🐭 Improves tissue function in aged mice Great discussion on the possibility of reversing senescence!
cell.com
Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells
Bi et al. propose the Senoreverse anti-aging strategy, which aims to reverse the proliferative arrest of senescent cells. Exosomal miR-302b is identified as a Senoreverse candidate that targets the ce...
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Demarialab @demarialab.bsky.social · 10/02/2025
🚨 Big news! 🚨 Our lab's latest paper by Jamil Nehme (@jamilnehme.bsky.social) is out now: Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer. Check it out! (doi.org/10.1038/s443...) Congrats, Jamil! #CancerResearch #CDK46 #BreastCancer
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