Snaebjornsson et al. explore a selective vulnerability in cancer elicited by targeting aldolase A, which causes energy imbalance and prevents further metabolic adaptations.

Aldolase A is one of the glycolytic enzymes that regulate cancer cell proliferation. A new study identifies aldolase A as a critical node that, when inhibited in cancer cells, turns glycolysis into an...

Aldolase A is one of the glycolytic enzymes that regulate cancer cell proliferation. A new study identifies aldolase A as a critical node that, when inhibited in cancer cells, turns glycolysis into an...

Snaebjornsson et al. explore a selective vulnerability in cancer elicited by targeting aldolase A, which causes energy imbalance and prevents further metabolic adaptations.