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Mark McCarthy

@markmccarthy985.bsky.social
709 followers 423 following 4 posts

Bluesky newbie. Twitter exile. Previously Professor of Diabetes in Oxford, now heading human genetics at Genentech. Living the California dream. Views my own. #YNWA

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Reposted by Mark McCarthy
Jane Natoli 🥑🚲🍍 @wafoli.bsky.social · 29/04/2025
Spending tonight with everyone’s favorite Glaswegians, Mogwai
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Reposted by Mark McCarthy
Jason / Method One @method1.bsky.social · 29/04/2025
MOGWAI - San Francisco, April 28, 2025 Because sometimes you just want to atomize yourself in a wave of guitar feedback
Mogwai performing at the Regency Ballroom, San Francisco, 4/28/25
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Mark McCarthy @markmccarthy985.bsky.social · 29/04/2025
It’s never a bad day when Mogwai shows up in town. First saw them in 1999. Love them more than ever…..
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Mark McCarthy @markmccarthy985.bsky.social · 15/01/2025
Exactly! Continues to amaze/frustrate me to find so many still place confidence in the value of differential expression/proteomics/methylation analyses of case control samples as a basis for causal inference.
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Reposted by Mark McCarthy
Giacomo Bartolucci (he) @gbart.bsky.social · 04/01/2025
1/n Some time ago my colleague, excellent cook, and friend Ivan told me: "Cacio e pepe is the recipe that I screw up more often. Let's make a project studying systematically the physics of that sauce". Prepare to get cheesy, I'm glad to share the Cacio e paper preprint: arxiv.org/abs/2501.00536
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Reposted by Mark McCarthy
Kimmo Aro @kihear.bsky.social · 04/12/2024
Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳 @nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore www.nature.com/articles/s41...
nature.com
Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks - Nature Communications
Identifying individuals at high risk for chronic diseases can improve prevention. Here, the authors show that blood metabolomics scores effectively stratify disease risk and compare favorably to genet...
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Reposted by Mark McCarthy
Kevin Mitchell @wiringthebrain.bsky.social · 28/11/2024
A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...
pnas.org
Encoding innate ability through a genomic bottleneck | PNAS
Animals are born with extensive innate behavioral capabilities, which arise from neural circuits encoded in the genome. However, the information ca...
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Reposted by Mark McCarthy
Ruairi Robertson @ruairirobertson.bsky.social · 19/10/2021
Inspiring talk by @christian_happi from @acegid on scaling up genomics infrastructure on the African continent for combatting infectious diseases, from malaria to COVID @QMULBartsTheLon #WHD21
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Mark McCarthy @markmccarthy985.bsky.social · 25/11/2024
Love this
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Reposted by Mark McCarthy
Alexis Battle @alexisbattle.bsky.social · 14/11/2024
Check out our new work led by @ashton_omdahl discussing matrix factorization across GWAS, accounting for sample overlap. Factors with varying polygenicity, enrichment for cell type / developmental stage... Ashton is speaking at #biodata24 today! www.biorxiv.org/content/10.1...
biorxiv.org
Sparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architectures
Complex trait-associated genetic variation is highly pleiotropic. This extensive pleiotropy implies that multi-phenotype analyses are informative for characterizing genetic variation, as they facilita...
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Reposted by Mark McCarthy
John Scalzi @scalzi.com · 23/11/2024
Others have noted it but I will too: The big reason Bluesky is so hot right now is that the people who add value to social media - the frequent posters in specific fields - are here now, talking to each other and creating the "spectator value" that draws users and attention.
theverge.com
Twitter’s heir apparent isn’t X or Threads — it’s Bluesky
The blue bird is dead. Long live the blue sky.
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Mark McCarthy @markmccarthy985.bsky.social · 18/11/2024
It’s fantastic to find so many friends already here. As others have noted, this feels like the early days of science twitter (RIP).
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