Reposted by Mark McCarthyJane Natoli 🥑🚲🍍 @wafoli.bsky.social · 29/04/2025Spending tonight with everyone’s favorite Glaswegians, Mogwai 2202
Reposted by Mark McCarthyJason / Method One @method1.bsky.social · 29/04/2025MOGWAI - San Francisco, April 28, 2025 Because sometimes you just want to atomize yourself in a wave of guitar feedback 2173
Mark McCarthy @markmccarthy985.bsky.social · 29/04/2025It’s never a bad day when Mogwai shows up in town. First saw them in 1999. Love them more than ever….. 0211
Mark McCarthy @markmccarthy985.bsky.social · 15/01/2025Exactly! Continues to amaze/frustrate me to find so many still place confidence in the value of differential expression/proteomics/methylation analyses of case control samples as a basis for causal inference. 082
Reposted by Mark McCarthyGiacomo Bartolucci (he) @gbart.bsky.social · 04/01/20251/n Some time ago my colleague, excellent cook, and friend Ivan told me: "Cacio e pepe is the recipe that I screw up more often. Let's make a project studying systematically the physics of that sauce". Prepare to get cheesy, I'm glad to share the Cacio e paper preprint: arxiv.org/abs/2501.00536 24496166
Reposted by Mark McCarthyKimmo Aro @kihear.bsky.social · 04/12/2024Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳 @nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore www.nature.com/articles/s41...nature.comMetabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks - Nature CommunicationsIdentifying individuals at high risk for chronic diseases can improve prevention. Here, the authors show that blood metabolomics scores effectively stratify disease risk and compare favorably to genet... 0115
Reposted by Mark McCarthyKevin Mitchell @wiringthebrain.bsky.social · 28/11/2024A wonderful paper from @tonyzador.bsky.social and colleagues: Encoding innate ability through a genomic bottleneck www.pnas.org/doi/10.1073/...pnas.orgEncoding innate ability through a genomic bottleneck | PNASAnimals are born with extensive innate behavioral capabilities, which arise from neural circuits encoded in the genome. However, the information ca... 411942
Reposted by Mark McCarthyRuairi Robertson @ruairirobertson.bsky.social · 19/10/2021Inspiring talk by @christian_happi from @acegid on scaling up genomics infrastructure on the African continent for combatting infectious diseases, from malaria to COVID @QMULBartsTheLon #WHD21 001
Reposted by Mark McCarthyAlexis Battle @alexisbattle.bsky.social · 14/11/2024Check out our new work led by @ashton_omdahl discussing matrix factorization across GWAS, accounting for sample overlap. Factors with varying polygenicity, enrichment for cell type / developmental stage... Ashton is speaking at #biodata24 today! www.biorxiv.org/content/10.1...biorxiv.orgSparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architecturesComplex trait-associated genetic variation is highly pleiotropic. This extensive pleiotropy implies that multi-phenotype analyses are informative for characterizing genetic variation, as they facilita... 0218
Reposted by Mark McCarthyJohn Scalzi @scalzi.com · 23/11/2024Others have noted it but I will too: The big reason Bluesky is so hot right now is that the people who add value to social media - the frequent posters in specific fields - are here now, talking to each other and creating the "spectator value" that draws users and attention.theverge.comTwitter’s heir apparent isn’t X or Threads — it’s BlueskyThe blue bird is dead. Long live the blue sky. 912548906910
Mark McCarthy @markmccarthy985.bsky.social · 18/11/2024It’s fantastic to find so many friends already here. As others have noted, this feels like the early days of science twitter (RIP). 0233