Abstract. In this work, we explore the structure and charge distribution within carbonyl compounds. It is routine in textbook explanations to attribute the

Abstract. The stabilization of positive and negative charges by alkyl groups (in particular) in organic compounds is often described as polarizability, but

The inductive effect is generally taught as being transmitted through the σ-bond framework in organic molecules, diminishing with each bond. This historical position does not align with more recent studies, and we show that the inductive effect in neutral molecules is effectively limited to one bond. Evidence of onward transmission (e.g., 13C NMR chemical shifts) should be viewed with scepticism. In charged species, where an electron-donating functional group is coupled with a suitably disposed electron-withdrawing substituent, the effect is transmitted over more bonds. These examples should be considered as polarizability rather than ‘purely’ inductive. Examples that are commonly described as a through-space field effect are better explained by polarizability/orbital perturbation. This work presents a more complete view of the inductive effect and its interface with polarizability.

Hybridization is a bonding model, universally used in organic chemistry, which allows consideration of two-electron localized bonds in organic molecules. Without hybridization, it is almost impossible...

A dysprosium amide–alkene complex shows soft magnetic hysteresis loops up to 100 kelvin, arising from the high charge density of the amide ligands and the structural role of the pendant alkene.

We find there to be no significant difference between the inductive effects of four representative alkyl groups as determined by Hirshfeld charge analysis. The use of alkyl group electronegativity val...

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The inductive effect is a central concept in chemistry and is often exemplified by the pKa values of acetic acid derivatives. The reduction in pKa is canonically attributed to the reduction in the ele...

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It is commonly stated that alkyl groups exert an inductive electron-releasing effect when compared to hydrogen. This information has been given in numerous organic chemistry textbooks over the last 75...