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Marie-Amandine Chabry

@marie-a-chabry.bsky.social
40 followers 68 following 0 posts

MD-PhD student at l’École de l’INSERM 🩺 Currently looking at how ventricles grow in the heart 🫀 @pasteur.fr @institutimagine.bsky.social

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Reposted by Marie-Amandine Chabry
Sigolène Meilhac @meilhacsigolene.bsky.social · 24/09/2025
New publication | Science Advances www.science.org/doi/10.1126/...
science.org
Plasticity of ventricle position after heart looping in heterotaxy with right isomerism
The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.
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Reposted by Marie-Amandine Chabry
PLOS Biology @plosbiology.org · 01/04/2025
Creating an asymmetric heart: @tbonnely.bsky.social @audreydsg.bsky.social @meilhacsigolene.bsky.social &co identify Notch3 as a novel asymmetric factor in lateral plate mesoderm that acts as a genetic modifier of NODAL to regulate #heart #morphogenesis @plosbiology.org 🧪 plos.io/42q6H4L
Left: Expression of Notch3 (white) detected by whole mount RNAscope ISH in an E8.5d wild-type embryo, shown in frontal views (top, cranial part of the embryo) and transverse section (bottom). Filled and empty arrowheads point to high and low expression, respectively. Right: Segmentation of the cardiac region in 3D images, to quantify gene expression in the left (white) or right (yellow) heart field. The heart tube is colored in red. Somites are outlined by white dotted lines. Expression of Notch3 within the segmented second heart field is extracted in the right panel.
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Reposted by Marie-Amandine Chabry
Institut Imagine @institutimagine.bsky.social · 11/02/2025
📣 Journée internationale des femmes et des filles de science à l'Institut Imagine ! Nous célébrons aujourd'hui toutes celles qui, par leur passion et leur détermination, font avancer la recherche et l’innovation : cette journée permet de mettre en lumière leur parcours, parfois semé d’obstacles.
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Reposted by Marie-Amandine Chabry
Audrey Desgrange @audreydsg.bsky.social · 27/01/2025
🚨 Postdoc wanted 🚨 Ever wondered how mechanical forces shape the heart tube during embryogenesis?… I am looking for a postdoc with a background in developmental biology or biophysics to investigate this new topic as part of an ANR-JCJC 🚀🔬 Don’t hesitate to contact me 🤓🔗
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