Reposted by Margaret GadekDena Dubal @denadubal.bsky.social · 12/04/2025Congratulations @margaretgadek.bsky.social on a wildly successful PhD! On to the MD! 071
Reposted by Margaret GadekScience Magazine @science.org · 11/03/2025A new #ScienceAdvances study examines how aging-driven reactivation of genes in the silent X chromosome affects cognitive decline in female mice. #WomensHealth scim.ag/3DxPjl7scim.agAging activates escape of the silent X chromosome in the female mouse hippocampusAging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse. 1407
Reposted by Margaret GadekScience Magazine @science.org · 11/03/2025A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵) 429082
Margaret Gadek @margaretgadek.bsky.social · 06/03/2025Thanks for sharing our work! The second X chromosome is a fascinating part of our genome. 020
Reposted by Margaret GadekDena Dubal @denadubal.bsky.social · 06/03/2025"We could all use a little more X!" Thrilled our new study is out. Aging "wakes up" the silent X chromosome in the female brain - and this contributes cognitive resilience. Spearheaded by @margaretgadek.bsky.social in Science Advances. www.science.org/doi/10.1126/...science.orgAging activates escape of the silent X chromosome in the female mouse hippocampusAging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse. 25123
Margaret Gadek @margaretgadek.bsky.social · 05/03/2025Our new Science Advances paper reveals activation of the silent X chromosome as a mechanism of female resilience in cognitive aging www.science.org/doi/10.1126/... Many thanks to @denadubal.bsky.social for your mentorship on this project!!science.orgAging activates escape of the silent X chromosome in the female mouse hippocampusAging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse. 193