One NYU endocrinology fellowship position available outside the match for PSTP residents building a research career in metabolism and cancer cachexia.

Scientists are getting closer to understanding the wasting and fatigue that often accompanies cancer. Treatments could be on the horizon.

High-fat, high-sucrose (HFHS) diets are established risk factors for obesity. In the intestine, sucrose is hydrolyzed into glucose and fructose, with fructose being taken up by epithelial cells and ph...

The Holman Division of Endocrinology, Diabetes & Metabolism at NYU Langone Health is seeking an academically oriented physician

Cancer cachexia is a wasting syndrome with outsized impact on morbidity and mortality. Neither the etiology of cachexia, nor its consequences on patient physiology and outcomes, are well-understood. H...

Overview The Beyond Mammals: Exploring Cancer Models series will feature three webinars, each focused on one non-mammalian animal model and its applicability to cancer research. Each webinar will high...

British Journal of Cancer - Multi-node inhibition targeting mTORC1, mTORC2 and PI3Kα potently inhibits the PI3K/AKT/mTOR pathway in endometrial and breast cancer models

A year of scientific creativity

Trinh et al. demonstrate that basal IL-6 activity regulates fat uptake and storage. IL-6 enhances skeletal muscle fat uptake, promotes fat release from subcutaneous adipose tissue during fasting, and ...

In mice, prolonged consumption of a high-fat diet decreases interest in calorie-rich foods as a result of reduced neurotensin expression and signalling, which uncouples hedonic feeding behaviour linke...

Cachexia is a systemic wasting syndrome prevalent in patients with cancer that significantly affects quality of life, health care costs, and therapeutic outcomes. Despite its clinical importance, cach...

In mice, silencing a set of neurons in the brain’s hypothalamus leads to chewing behaviours, even when food is unavailable.

Dietary fructose enhances tumour growth in animal models of melanoma, breast cancer and cervical cancer indirectly via metabolite transfer.

Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.

“Researchers, public health and health care groups, advocates, industry, and the public must put tackling diet-related disease at the top of their priority list.”