iiinova — where your digital self keeps evolving

Reposted by Marco Silva

Tiago Beites @tiagobeites.bsky.social · 07/12/2025

Mycobacterium tuberculosis is an outlier in many ways. One of them is keeping a high degree of functional redundancy despite its obligate pathogen lifestyle. In this review, we reflect on the biological meaning of M. tuberculosis functional redundancies. journals.plos.org/plospathogen...

journals.plos.org

Essential redundancies fuel Mycobacterium tuberculosis adaptation to the host

Redundancy in biology is, at a glance, counterintuitive because if the function of two gene products completely overlaps then, throughout the course of evolution, one of the genes will likely accumula...

13714

Reposted by Marco Silva

Tiago Beites @tiagobeites.bsky.social · 15/04/2025

Long-chain fatty acids can be carbon sources for pathogens but are also potent antimicrobials. In our latest work, we explored the question of how Mycobacterium tuberculosis avoids getting killed by a preferred carbon source. www.biorxiv.org/content/10.1...

biorxiv.org

The Mycobacterium tuberculosis long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infection

The human pathogen Mycobacterium tuberculosis (Mtb) thrives in lipid-rich microenvironments. Long-chain fatty acids (LCFA) are some of the most abundant lipids encountered by Mtb during infection. Mtb...

094

Reposted by Marco Silva

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 15/04/2025

The Mycobacterium tuberculosis long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infection www.biorxiv.org/content/10.1101/202…

194

Marco Silva @marcopsilva.bsky.social · 22/02/2025

It was really great hosting you @oneyrolles.bsky.social! Fantastic science, great conversations, and a truly enjoyable time. Glad you had a great experience!

030

Reposted by Marco Silva

Olivier Neyrolles @oneyrolles.bsky.social · 21/02/2025

Huge thanks to @marcopsilva.bsky.social, Thales Costa and all the students for the kind invite to speak at the @i3suporto.bsky.social Student symposium! 🌟 Top-notch organization, amazing vibes, and a truly warm welcome, an unforgettable experience! 🙏 #i3Ssymposium

084

Marco Silva @marcopsilva.bsky.social · 12/02/2025

First time at #EMBOtuberculosis presenting a part of my PhD work through a flash talk and poster presentation. Great to finally meet the TB community! Incredible experience in India, with amazing science, wonderful people, and delicious food! 🇮🇳

151

Reposted by Marco Silva

Tiago Beites @tiagobeites.bsky.social · 12/02/2025

What a great conference #EMBOtuberculosis has been! Amazing science, amazing food and a very friendly community! And it was a pleasure to share the work we’re developing at i3S U. Porto.

1133

Reposted by Marco Silva

Tiago Beites @tiagobeites.bsky.social · 17/11/2024

Introducing my wonderful team at i3S - University of Porto. PhD student @marcopsilva.bsky.social and research fellow @alexjpinto.bsky.social

295