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Conchi Manzano

@manzanoc.bsky.social
180 followers 246 following 1 posts

Plant Developmental Biologist | Researcher at HHMI and UC Davis | Brady lab | Former Marie S. Curie fellow | Love Science, Arts and Philosophy

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Reposted by Conchi Manzano
mariebarberon.bsky.social @mariebarberon.bsky.social · 04/09/2026
PADiBa2026 was a blast! 🌱 A huge thank you to everyone who made it such a fantastic meeting, with exciting science, great discussions and such a friendly community. Already looking to seeing many of you at PADiBa2028 in Utrecht!
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Toni Gabaldón @tonigabaldon.bsky.social · 10/06/2026
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
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Journal of Experimental Botany @jxbotany.bsky.social · 18/05/2026
We really enjoyed attending the 11th International Symposium on Root Development in Specchiolla, Italy earlier in May 📆 🫜🥔 To celebrate our sponsorship of the meeting, we’re assembling a virtual issue on root biology 🥕🍠 #PlantScience 🧪 #Rooting2026
Front cover of a postcard to advertise an upcoming virtual issue of the Journal of Experimental Botany titled 'Rooting 2026'. The editors are Pablo Manavella and Catharina Merchante. The issue is associated with the 11th International
Symposium on Root Development held on 4th-7th May 2026 in Specchiolla, Italy. The text reads "To mark Rooting 2026, we are assembling a collection of papers focused on plant roots. This collection brings together research spanning root development, agriculture, plant-pathogen interactions, and biotechnology."
The main image on the postcard is a hand drawn Schematic representation of the
Arabidopsis thaliana root apical meristem
in longitudinal and transverse sections. The cells are various colours. The JXB stand at the 11th International Symposium on Root Development. The table has lots of JXB merchandise and printed postcards of our upcoming special issues.
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Laura Ragni @lauraragni.bsky.social · 19/03/2026
Save the date! PADiBa goes back to beautiful Lausanne!
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The Plant Cell @theplantcell.bsky.social · 19/03/2026
Duplicated genes find their space: Spatial transcriptomics illuminates evolutionary fates (Min-Yao Jhu , Fabian van Beveren , Bruno Guillotin) doi.org/10.1093/plce... #PlantScience @aspbofficial
doi.org
Duplicated genes find their space: Spatial transcriptomics illuminates evolutionary fates
Gene and genome duplications are fundamental forces driving plant evolution, leading to relaxed selection and expanding genetic toolkits (Van de Peer et al
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Laura Ragni @lauraragni.bsky.social · 20/11/2025
It’s finally out! 🎉 Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth. 🔗 www.pnas.org/doi/10.1073/... #PlantSciences
pnas.org
An AINTEGUMENTA phosphoswitch controls bilateral stem cell activity during secondary growth | PNAS
Plant stem cells have the remarkable ability to give rise to distinct tissues and organs throughout development. Two concentric cylinders of active...
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Journal of Experimental Botany @jxbotany.bsky.social · 05/12/2025
🧬 🍅 SPECIAL ISSUE RESEARCH 🍅 🧬 MYB and WRKY transcription factors collaboratively regulate suberin biosynthesis in the tomato root exodermis. Antagonistic interactions may fine-tune suberization or act as a brake on overaccumulation - Jo et al. 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪
Fig. 2 (shortened, full legend in paper): Perturbations of SlMYB41, SlMYB92, and SlWRKY71 expression affect the suberization of tomato exodermis. (A) Percentage of cross-sections showing a non-suberized, an early suberized (suberin in <50% of exodermal cells), or a late suberized (suberin in >50% of exodermal cells) exodermis phenotype in hairy root cultures of the control (empty vector), CRISPR knockout lines [Slmyb41-ko, Slmyb92-ko, Slwrky71-ko(4), and Slwrky71-ko(5)], and overexpressing lines (SlMYB41-OX, SlMYB92-OX, and SlWRKY71-OX). The number above the bars represents the number (n) of individual roots examined in each genotype. Asterisks denotes statistically significant differences between each line in comparison with the empty vector control, whereas n.s. indicates no significant differences (P<0.05, χ2 test).
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Ian Henderson @hendersi.bsky.social · 20/11/2025
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis | Science www.science.org/doi/10.1126/... Very nice work from Holger Puchta & colleagues
science.org
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis
The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...
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Kevin Bird @stairwaytokevin.bsky.social · 13/11/2025
Happy to see this paper from my time with @spicybotrytis.bsky.social out in @theplantcell.bsky.social! Amanda, a fantastic PhD student with Dan, led this "phylo-functional" work & uncovered complex duplication & loss of a glucosinolate gene across the Brassicaceae affecting enantiomeric specificity
academic.oup.com
Convergence and constraint in glucosinolate evolution across the Brassicaceae
Studying a glucosinolate enzyme across the Brassicaceae shows evolution of plant specialized metabolism involves independent gene losses, distal duplicatio
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North American Arabidopsis Steering Committee @naascarabidopsis.bsky.social · 22/09/2025
Please share & RSVP to join the November 25th webinar! Hear from the 2025 Philip N. Benfey Arabidopsis Community Lifetime Achievement Awardees! bit.ly/naascawards @plantevolution.bsky.social
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Laura Ragni @lauraragni.bsky.social · 24/07/2025
Fresh from the press! For suberin lovers! Work led by @, my former PhD student and now postdoc in the team, with help of @sarahorvath.bsky.social and in collaboration with @tonnigrubeandersen.bsky.social . 🔗 DOI: doi.org/10.1016/j.ce... 1/4 #PlantScience
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Brady Lab @bradylabs.bsky.social · 01/07/2025
At long last, our paper on conservation and divergence of a nitrogen circuit upstream of NLP6/7 &NIR1 in Arabidopsis and tomato is published! It's an exciting combo of whole plant, in vitro, protoplast and systems bio approaches: tinyurl.com/nitrogencirc... @gozdedemirel.bsky.social
tinyurl.com
Conservation and divergence of regulatory architecture in nitrate-responsive plant gene circuits
Gene circuits that control transcriptional regulation of nitrate-responses have similarities and differences, despite the equivalent effects of nitrogen on
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Ari Pekka Mähönen @apmahonen.bsky.social · 02/07/2025
How plants sense injury in their barrier tissue, periderm? Painstakingly detailed and amazing work by post doc Hiroyuki Iida shows that wounding is sensed by the diffusion of two gases: ethylene and oxygen. @treebiocoe.bsky.social‬ @erc.europa.eu‬ 1/x 🧵 www.nature.com/articles/s41...
nature.com
Plants monitor the integrity of their barrier by sensing gas diffusion - Nature
A study using Arabidopsis shows that plants can monitor the integrity of their outer barriers by sensing gas diffusion, enabling them to initiate wound repair to prevent water loss and pathogen entry.
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Evan Bardot (he/him) @ebardot.bsky.social · 22/06/2025
Terrific rallying cry of an @socdevbio.bsky.social award lecture from @mads100tist.bsky.social at #icdb2025! Our work and community are important, #DevBio matters, and it’s up to us to tell everyone why. Don’t give the enshittifiers an inch!
Joaquín delivering a mental award lecture.
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Tonni Andersen @tonnigrubeandersen.bsky.social · 09/06/2025
Time for another paper from our lab! This time it’s about passage cells. This work originated from a collaboration with @lauraragni.bsky.social and was spearheaded by the super-talented @leoniekraska.bsky.social Below you will find a thread that explains our findings. www.cell.com/cell-reports...
cell.com
MYB68 regulates radial endodermal differentiation and suberin patterning
In this study, Kraska et al. identify MYB68 as a novel regulator of endodermal suberization, linked to the formation of distinct identities in the xylem-pole-associated endodermis. The research uncove...
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Kaisa Kajala @kaisakajala.bsky.social · 01/05/2025
Our work on MYBs and WRKY regulating suberin in tomato exodermis is now out in @jxbotany.bsky.social! 🍅 doi.org/10.1093/jxb/... 👩‍🔬 @leonardojo.bsky.social @riannekluck.bsky.social @marianasartur.bsky.social Sara Buti, Alex Cantó-Pastor @bradylabs.bsky.social 🌱 #PlantScience
doi.org
Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in the tomato exodermis
Abstract. Root barrier cell types, like the endodermis and exodermis, are crucial for plant acclimation to environmental stresses. Deposition of suberin, a
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Bipin Pandey @bipinpandey.bsky.social · 01/05/2025
Thrilled to see our work now online @nature.com This study reveals how individual root cells sense and respond to real, compacted soil environments. www.nature.com/articles/s41... beautiful spatial transcritomics of rice root in gel & soil conditions and huge credit to Mingyuan and colleagues.
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Tatsuya Nobori @tatsuyanobori.bsky.social · 27/03/2025
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy www.nature.com/articles/s41...
nature.com
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy - Nature Biotechnology
Volumetric DNA microscopy captures spatial information of RNA within an intact organism.
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Tonni Andersen @tonnigrubeandersen.bsky.social · 21/03/2025
Finally! Im so excited to present to culmination of many years of work from the fantastic Defeng Shen and some great collaborators. For details, I have made a digested thread below, but if you are more interested feel free to reach out (and read the paper of course). www.science.org/doi/10.1126/...
science.org
Apoplastic barriers are essential for nodule formation and nitrogen fixation in Lotus japonicus
Establishment of the apoplastic root barrier known as the Casparian strip occurs early in root development. In legumes, this area overlaps with nitrogen-fixing nodule formation, which raises the possi...
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PM Delaux @pierremarcdelaux.bsky.social · 05/03/2025
and we thought auxin signalling was "kind of solved".. TIR1-produced cAMP is essential for auxin response (in Arabidopsis thaliana) 🔽 www.nature.com/articles/s41...
nature.com
TIR1-produced cAMP as a second messenger in transcriptional auxin signalling - Nature
cAMP produced by the TIR1/AFB receptors of the main endogenous developmental plant hormone auxin acts as a true second messenger, revising the established paradigm of transcriptional auxin signalling.
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Joop Vermeer @joopvermeer.bsky.social · 26/02/2025
We are hiring! Are you interested in lateral root development and the cellular processes that accommodate these newly formed organs? If yes, apply! We are recruiting a Post-doc (from May 2025) and a PhD student (from September 2025). www.unine.ch/lbmc/jobs/
unine.ch
Jobs - Laboratory of cell and molecular biology
Join Our Team – Open Positions at the LBMC, Vermeer Lab.   We are excited to announce two open positions, please get in touch with Prof. Dr. Joop Vermeer: josephus.vermeer@unine.ch Applications open f...
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Brady Lab @bradylabs.bsky.social · 27/03/2024
I am really proud to share our study on microbes, Striga and sorghum is now online in Cell Reports! doi.org/10.1016/j.ce... and the press release is here: biology.ucdavis.edu/news/soil-mi... This was an epic effort led by the incredible Dorota Kawa, +B. Thiombiano, H. Bouwmeester, J. Raiijmakers...
doi.org
Redirecting
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Brady Lab @bradylabs.bsky.social · 03/12/2024
I am so excited to share Dr. C Manzano’s work: she demonstrates the developmental timeline, function and genetic regulation of the polar lignin cap in the tomato root. It functions as a distinct intercellular barrier from the Casparian strip and is repressed in inner layers. rdcu.be/d10Pd
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