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Leonel Malacrida

@malacridalab.bsky.social
389 followers 502 following 60 posts

Head of the Advanced Bioimaging Unit, joint center Udelar & Inst. Pasteur Montevideo. Imaging Scientist CZI and LABI executive committee.

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Leonel Malacrida @malacridalab.bsky.social · 25/02/2026
Congrats Liz and Jorge!
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Leonel Malacrida @malacridalab.bsky.social · 25/02/2026
One more @biophysicalsoc.bsky.social meeting and counting… #BPS2026! Great as usually, meeting old friends and making new ones. This time was my first one with of my students #JessicaRossello postdoc at @IPMontevideo developing new methods for bacterial wall studies 🔬🌈
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AIC at Janelia @aicjanelia.bsky.social · 28/01/2026
Check out this new approach to colocalization analysis from @owfpuls.bsky.social along with members of the AIC and Advanced Bioimaging Unit teams, now out in @jcellsci.bsky.social! journals.biologists.com/jcs/article/...
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Leonel Malacrida @malacridalab.bsky.social · 29/01/2026
It’s great to see this document supporting colocalization via Phasor analysis of HSI data, now available on confocal microscopes. Thanks to @scopeshifu.bsky.social and @aicjanelia.bsky.social teams for their collaboration starting in 2022 during the Imaging Latinoamérica workshop.
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Leonel Malacrida @malacridalab.bsky.social · 14/01/2026
Thanks @digmanlab.bsky.social and the rest of the FLAIR Workshop organizers for the kind invitation to present www.phasorpy.org Great workshop with amazing lectures and practical activities. sites.uci.edu/aimlfdworksh...
sites.uci.edu
LFD/AIM Workshop 2026
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Leonel Malacrida @malacridalab.bsky.social · 14/12/2025
Happy to share a chat we had with Peter O’Toole on his podcast “The Microscopists.” I'm extremely honored to be part of this series. We discuss my journey into science, memories, and the recent moment in Uruguay leading the Advanced Bioimaging Unit. themicroscopists.bitesizebio.com/episodes/leo...
themicroscopists.bitesizebio.com
The Microscopists | Leonel Malacrida (Universidad de la República & Institut Pasteur Montevideo, Uruguay)
In this episode of The Microscopists, Peter O’Toole sits down with Leonel Malacrida of Universidad de la República & Institut Pasteur Montevideo, Uruguay.Leonel reflects on his early ambition of be...
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Leonel Malacrida @malacridalab.bsky.social · 18/11/2025
I am grateful and thoughtful to @biologists.bsky.social for supporting @muktarlawan.bsky.social visit to our lab in 🇺🇾. Muktar has been a wonderful visitor and now an ambassador for HSI and phasor analysis at @BioRTCNig in 🇳🇬 and across Africa. Looking forward to more messages in the bottle!
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Leonel Malacrida @malacridalab.bsky.social · 15/11/2025
This project looks ahead a decade or more. The collaborative atmosphere and strategic planning on RI regarding Integrative Structural Biology+Bioimaging are the present and future collaborations for our regions. Looking forward to continuing this fantastic consortium!
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Leonel Malacrida @malacridalab.bsky.social · 15/11/2025
Over the past days Andres Kamaid and I attended to the closing meeting of the “Regional Hubs project RI_Hubs_EULAC. Great results and exciting next steps to strengthen EU–LAC cooperation in RI Bioimaging+Structural Biology 🇵🇹🇧🇷🇪🇸🇺🇾🇮🇹🇵🇪 🤝🌎
@eurobioimaging.bsky.social @latambioimaging.bsky.social 
@instruct-eric.bsky.social
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Leonel Malacrida @malacridalab.bsky.social · 10/11/2025
@LatamBioimaging 2025 meeting started with the aperture by the chairs Kildare Miranda, Lia Pietrasanta, Chris Wood and the one an only “Oliver “ Then our opening keynote lecture by @FerStefaniLab with his fantastic work on Super Resolution Microscopy!
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Leonel Malacrida @malacridalab.bsky.social · 31/10/2025
A week ago we installed the new 2P-laser #Insight X3 by @spectraphysics.bsky.social This laser is now the new heart of our #DIVER microscope. Expanding our opportunity for spectroscopy #690-1300 #WavelengthMixing #FLIM #CARS #Pump_Probe We are very excited!!!
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Leonel Malacrida @malacridalab.bsky.social · 30/10/2025
Likewise Rumiana! Thanks Antonio Costa-Filho for the invitation!
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Leonel Malacrida @malacridalab.bsky.social · 28/10/2025
Many thanks #AntonioCostaFilho for the kind invitation to participate in the pre-meeting #SBBf course “Phase separation at membrane interphases: Biomolecular condensates in Actions”. Happy share session with #RumianaDimova #Condensates #LLPS #Bioimaging #Phasors #DANprobes
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Leonel Malacrida @malacridalab.bsky.social · 25/10/2025
Yes, this is great application for bioluminescence that Michelle and other colleagues are developing. I still remember first time Enrico Gratton share with me his idea in Buzios-Brazil!
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Leonel Malacrida @malacridalab.bsky.social · 25/10/2025
Thanks Christophe for remembering out discussion in Montevideo. I thought it was a good idea since modulated filters will catch one molecule at a time. I'm glad the authors also saw the potential.
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Leonel Malacrida @malacridalab.bsky.social · 15/10/2025
I'm thrilled to share this with the community. Take a look, feedback is always very much welcome! Congrats Bruno Pannunzio Marcelo Leomil Zoccoler !
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Leonel Malacrida @malacridalab.bsky.social · 15/10/2025
-FLIM calibration, multi-harmonic analysis, filtering/thresholding, Cursors selection, average lifetimes (tau mod, tau phase, tau normal), two components (multi-components coming soon), and FRET module. -HSI analysis using the same tools, just under a bottom push. - Sample data for FLIM and HSI.
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Leonel Malacrida @malacridalab.bsky.social · 15/10/2025
Extremely excited to share quite an achievement for our group. Two years ago, we started #PhasorPy (www.phasorpy.org, now in our v0.8). In parallel, Bruno Pannunzio, in collaboration with Marcelo Zoccoller, led the hashtag#Napari_Phasors plugin v0.1 for FLIM & HSI phasor analysis.
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Leonel Malacrida @malacridalab.bsky.social · 25/09/2025
Thanks to @ipmontevideo.bsky.social #Udelar #HospitaldeClinicas #FMed all my collaborators from #AdvancedBioimagingUnit and across the world and @chanzuckerberg.bsky.social for all the support over the years!
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Leonel Malacrida @malacridalab.bsky.social · 25/09/2025
Extremely honored to be included in 2026 #ThePhotonics100 #Electrooptics for “the innovators, the boundary-pushers, the disruptors, the out-of-the-box thinkers and the R&D ‘rock stars’” driving the industry forward. Happy to represent Uruguay & Latin America www.electrooptics.com/article/leon...
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Leonel Malacrida @malacridalab.bsky.social · 18/09/2025
Big part of #LABI, Latin America grantees and friends reunited at #ImagingTheFuture 2025 @cziscience.bsky.social Thanks!
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Leonel Malacrida @malacridalab.bsky.social · 18/09/2025
Thanks @cziscience.bsky.social #ImagingTheFuture for reuniting @LatamBioimaging another year. The #UBA participated with a poster Marcela Diaz and a Demo #phasorpy showing all our work in the past years. Intense and stimulating discuss drives us to next steps in shaping the future
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Leonel Malacrida @malacridalab.bsky.social · 14/09/2025
#ImagingTheFuture2025 @chanzuckerberg.bsky.social Another year traveling with the one and only “Oliver” Andres Olivera #LABI. Looking forward to stimulating discussions and contributing to shaping “Biology in Action.”
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Leonel Malacrida @malacridalab.bsky.social · 28/07/2025
New preprint by @UBA Micaela LopassioMicaela MJGarcia Quantitative and unbiased lung alveolar septum assessment in a LPS experimental mouse model using 2D-spatial correlation image analysis from hematoxylin and eosin slides. biorxiv.org/content/10.110… 🫁🔬💻🟰results
biorxiv.org
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Leonel Malacrida @malacridalab.bsky.social · 30/06/2025
We have a small fellowship bursary, but we strongly support participants from Latin America and around the world to apply for fellowships: #LABI labi.lat/2025/06/04/l... Deadline July 7, 2025 #GBI #I4A globalbioimaging.org/i4a Deadline August 15, 2025.
labi.lat
LABI Fellowships: Second call 2025
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Leonel Malacrida @malacridalab.bsky.social · 30/06/2025
I am happy to announce the open call for our "6th Workshop in Advanced Microscopy and Biophotonics" It will be held from November 22nd to 28th in Montevideo, Uruguay. It will cover advanced technologies and techniques as usual #FLIM #HSI #Phasors #FCS #SR #SPIM #2P pasteur.uy/cursos-y-cha...
pasteur.uy
6th Workshop in Advanced Microscopy and Biophotonics - Institut Pasteur
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Leonel Malacrida @malacridalab.bsky.social · 20/06/2025
The Latin American crew (25 👩‍🔬👨‍🔬👩‍💻👨‍💻) gathered at the #webersymposium2025. Multiple generations celebrated our proud roots 🇧🇷🇦🇷🇨🇱🇺🇾🇨🇺🇧🇴. Thanks @chanzuckerberg.bsky.social, for enabling 13 travel fellowships to attend this great meeting at the beautiful Genoa 🇮🇹
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Leonel Malacrida @malacridalab.bsky.social · 14/06/2025
Part of the team #UBA #LeconteLudovic #Marceladiaz and good friend #RamiroTomasina ready to go to #WeberSymposium2025 #Genova 🇮🇹 #Garcia__Majo already in Genoa I am excited to be accompanied by a great team this time! 🇺🇾
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Global BioImaging @globalbioimaging.bsky.social · 13/05/2025
🌍 The 2nd #Imaging4All call is OPEN 🎉 Researchers in LMICs can apply for fully funded visits to access imaging technologies & training worldwide. 🔗 Info: www.globalbioimaging.org/i4a 🧪 Questions? i4a_support@embl.de 🔬 Imaging facilities—please share & host a grantee!
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Leonel Malacrida @malacridalab.bsky.social · 17/04/2025
📣Abstract submission and registration still open for the 2025 Weber Symposium! Follow the link: www.webersymposium.com If you are MSc/PhD/PostDoc based in Latin America, you are eligible for full fellowships. 🚨 Deadline April 30th 🙏 Pass the word!
webersymposium.com
International Weber Symposium
The 12th International Weber Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, "Weber Symposium", will be held in Genoa, Italy, on June 15-20, 2024.
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Leonel Malacrida @malacridalab.bsky.social · 17/04/2025
📣Abstract submission and registration still open for the 2025 Weber Symposium! Follow the link: www.webersymposium.com If you are MSc/PhD/PostDoc based in Latin America, you are eligible for full fellowships. 🚨 Deadline April 30th 🙏 Pass the word!
webersymposium.com
International Weber Symposium
The 12th International Weber Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, "Weber Symposium", will be held in Genoa, Italy, on June 15-20, 2024.
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Leonel Malacrida @malacridalab.bsky.social · 14/04/2025
Muktar is now our ambassador in Nigeria, sharing the power of HSI-Phasors for basic biomedical problems. His impact on our group has been significant, and while we'll miss him, I believe this is just the start of a strong bond between our groups 🇺🇾🔬🇳🇬 See you soon Muktar! Safe travels
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Leonel Malacrida @malacridalab.bsky.social · 14/04/2025
Today we are saying goodbye to a fantastic visitor we host in the past 3 months Muktar Lawan from 🇳🇬 BioRTC He has learned #HSI & #Phasors for studying neurodegeneration in African ancients cell lines Thanks @chanzuckerberg.bsky.social @focalplane.bsky.social Mahmoud Maina for support & trust
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Leonel Malacrida @malacridalab.bsky.social · 12/04/2025
Wonderful week full of learning and camaraderie. Thanks to all the participants, professors, and companies/funders who made #CFMO2025 a success! Congratulations Marcela Diaz Paola Lepanto for another great course #ImagingTheFuture 🔬🧑‍🔬🥼🧑‍💻👩‍💻 @clairebrown514.bsky.social @chanzuckerberg.bsky.social
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Leonel Malacrida @malacridalab.bsky.social · 06/04/2025
Chau Porto 🇵🇹 it was great experience and amazing opportunity for #AdvancedBioimagingUnit @phasorpy to share what we do. Thanks to local organizers @pm_sampaio Maria Acevedo @ALM_i3S And A. Rossetta @FLIMLabs J. Pearson @leicamicrosystems.bsky.social for the fruitful discussion #FLIM #Phasors
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Leonel Malacrida @malacridalab.bsky.social · 01/04/2025
Great talk by Bruno Pannunzio today at #15_OMI4Bio2025 course about #Phasor properties for #FLIM analysis @ALM_i3S @PhasorPy @advanced_unit
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Leonel Malacrida @malacridalab.bsky.social · 31/03/2025
Today #15_OMI4Bio2025 course at @ALM_i3S started with #FLIM and #Phasors introduction. This course is also part of the @RI_Hubs_EULAC consortium supported by EULAC group of interest.
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Leonel Malacrida @malacridalab.bsky.social · 29/03/2025
#PhasorPy Uruguayan team @advanced_unit ready to takeoff! Final destination #Porto 🇵🇹 @ALM_i3S for “Course in optical microscopy imaging for bioscience” #FLIM #Phasors Here we go!!!
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Leonel Malacrida @malacridalab.bsky.social · 11/03/2025
Beautiful work Jörg! Congratulations to all the team!
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Leonel Malacrida @malacridalab.bsky.social · 10/03/2025
New Review Alert! "Fluorescence Phasor Analysis: Fundamental Principles and Biophysical Applications" in Biophysical Reviews! This collaboration with Luis Gonzalez-Felcha and Alvaro Recoulat discusses the fundamentals of #phasor_analysis for #Fluorescence studies in #biophysics. 👉 rdcu.be/ecEH2
rdcu.be
Fluorescence phasor analysis: basic principles and biophysical applications
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Leonel Malacrida @malacridalab.bsky.social · 21/02/2025
After 3-weeks of intense training at #UBA, #MuktarLawan from #BioRTCNig is now able to handle cell culture 🧫 and fundamentals of optical microscopy 🔬 on his own. He is ready to move on to the next level, #HSI 🌈 and #Phasor 💻, to study nuclear dynamics in health/disease
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Leonel Malacrida @malacridalab.bsky.social · 20/02/2025
New paper from the UBA, #Marceladiaz in collaboration with #carlos_robello #AndresCabrera Modulation of host cell membrane biophysics dynamics by Neospora caninum: A study using LAURDAN fluorescence with hyperspectral imaging and phasor analysis onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Modulation of host cell membrane biophysics dynamics by Neospora caninum: A study using LAURDAN fluorescence with hyperspectral imaging and phasor analysis
Neospora caninum is known to manipulate host cell organelles and recruit lipids for its survival. However, the impact of this lipid redistribution on host cell membranes remains poorly understood. Th...
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Leonel Malacrida @malacridalab.bsky.social · 20/02/2025
Thanks Jörg! We appreciate twice this coming from you! It was a great pleasure to meeting you in #BPS2025, see you in Genoa at Weber meeting!
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Leonel Malacrida @malacridalab.bsky.social · 19/02/2025
Congratulations Chris and Sudha for the great meeting!
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Biophysical Society @biophysicalsoc.bsky.social · 17/02/2025
Today's Future of Biophysics Symp features the work of four up-and-coming researchers:
buff.ly
The Biophysical Society > Meetings & Events > Annual Meeting > 2025 Annual Meeting > Program > Scientific Sessions > Future of Biophysics
Coming soon to a lab near you - “The Future of Biophysics” - We are excited to showcase four incredible young researchers at this year’s Symposium supported by the Burroughs Wellcome Fund. The 2025…
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Leonel Malacrida @malacridalab.bsky.social · 18/02/2025
🙏 thanks Gabriela!
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Jörg Enderlein @joergenderlein.bsky.social · 17/02/2025
Leonel Malacrida (@malacridalab.bsky.social) just highlighted the upcoming Gregorio Weber Meeting in his plenary talk—this time in the stunning city of Genoa. A must-attend event for anyone interested in fluorescence (and not just because I’ll be giving a talk there! 😀).
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Jörg Enderlein @joergenderlein.bsky.social · 17/02/2025
If you’re interested in fluorescence lifetime imaging, be sure to check out PhasorPy, a powerful Python package developed by Leonel Malacrida (@malacridalab.bsky.social) and colleagues. Learn more at www.phasorpy.org.
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Chris Yip @cyclocrossguy.bsky.social · 18/02/2025
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Leonel Malacrida @malacridalab.bsky.social · 18/02/2025
Still overwhelmed from an amazing session at #BPS2025! Huge thanks to @biophysicalsoc.bsky.social and @BWFUND for including me in this year's #TheFutureofBiophysics Burrough Wellcome Fund Symposium. Congrats to my fellow colleagues—what an honor to share this experience!
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