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Alexandre Gaspar Maia

@maialab.bsky.social
85 followers 148 following 36 posts

Biologist | Associate Professor | Mayo Clinic l #LabFunEpi

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Alexandre Gaspar Maia @maialab.bsky.social · 18/05/2026
Nerding out about transcription regulation at the 11th Annual UND Epigenetics and Epigenomics Symposium.
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Alexandre Gaspar Maia @maialab.bsky.social · 03/03/2026
The Bernstein lab alumni in the house, #KSEpigenetics26 at the Keystone Epigenetics meeting in Geneva. With Emily Bernstein and Zulekha Qadeer.
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Alexandre Gaspar Maia @maialab.bsky.social · 02/03/2026
Great visit to @unil.bsky.social in Lausanne to chat about how to integrate Epigenomic single cell profiling with spatial resolution with Denarda Dangaj. Thank you for hosting! #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 03/02/2026
“Sold out show” for Dr. Mihai Dumbrava’s thesis defense.
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Alexandre Gaspar Maia @maialab.bsky.social · 01/02/2026
The Mayo Clinic Graduate School of Biomedical Sciences @mayoclinic had its first round of recruitment interviews for the PhD program in Rochester MN. It was lovely to see the energy and enthusiasm of all these young scientists.
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Alexandre Gaspar Maia @maialab.bsky.social · 08/01/2026
www.cell.com/cell-reports... Great preview of our most recent paper by @afarkkila.bsky.social and @anna-vaharautio.bsky.social. Thank you both for the great summary.
cell.com
Decoding the epigenetics of persister states in ovarian cancer
Dumbrava et al. map a unified epigenetically primed persister state in high-grade serous ovarian carcinoma using single-nucleus multi-omics. Their work uncovers a chromatin-encoded tolerance program t...
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Alexandre Gaspar Maia @maialab.bsky.social · 06/01/2026
www.sciencedirect.com/science/arti...
sciencedirect.com
Single-cell resolution of an open chromatin signature in persister tumor cells
Cancer can recur when a subset of tumor cells, termed persister cells, survive therapy and re-enter the cell cycle. Through single-nucleus multi-omic …
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Alexandre Gaspar Maia @maialab.bsky.social · 22/12/2025
Happy holidays!
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Alexandre Gaspar Maia @maialab.bsky.social · 11/11/2025
www.linkedin.com/posts/gaspar...
linkedin.com
#ocmf2025 | Alexandre Gaspar Maia
#OCMF2025 was a big success! Really great to catch up with the best science around ovarian cancer and bring the whole lab for old and new collaborations! Mihai Dumbrava Wazim Mohammed Ismail, PhD Sier...
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Alexandre Gaspar Maia @maialab.bsky.social · 04/11/2025
The #LabFunEpi turned 8! Thank you for the support and great experiments along the way. And specially a great thank you to Sierra Hamernick for the cake! @wazimismail.bsky.social @yiwenxie.bsky.social
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Alexandre Gaspar Maia @maialab.bsky.social · 01/10/2025
Fusion confenrence on “Stem cells and Cancer” in Malta, is the best way to reunite with my PhD advisor @mrsantos.bsky.social and old friend from UCSF Daniel Lim.
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Reposted by Alexandre Gaspar Maia
DOD OCA @ocacademy.bsky.social · 21/09/2025
September is Ovarian Cancer Awareness Month!
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Alexandre Gaspar Maia @maialab.bsky.social · 20/09/2025
MD/PhD student Mihai Dumbrava from our #LabFunEpi presenting his work about an epigenetic persister cell signature using single using single cell ATAC+RNA profiling of HGSC patient samples at the AACR Ovarian cancer meeting in Denver CO.
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Alexandre Gaspar Maia @maialab.bsky.social · 13/09/2025
When I was a graduate student the process of DNA de-methylation was a complete mystery. Until Dr. Anjana Rao described for the first time how the TET enzymes mediate the process. It was amazing to meet one of my scientific heroes this week.
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Alexandre Gaspar Maia @maialab.bsky.social · 29/06/2025
Three generations of summer students together for the Rochester mini renaissance fest. #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 21/06/2025
Great way to spend the hottest day so far in Minnesota: the MD/PhD (MSTP) retreat at Mayo Clinic, Rochester.
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Alexandre Gaspar Maia @maialab.bsky.social · 10/06/2025
Yesterday I was invited by the graduate students to talk about my career path. Did not expect to have so much fun digging into my PhD and postdoc and eventually some undergraduate treasures: Perkinsus atlanticus was my first organism of interest and how I became fascinated with nucleus.
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Alexandre Gaspar Maia @maialab.bsky.social · 02/06/2025
The Ovarian Cancer Midwest focus meeting is now open for registration. Please join in Minneapolis, MN November 10-11 for an amazing line up of speakers including Ernst Lengyel, University of Chicago, and Joan Brugge, Harvard Medical School.
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Alexandre Gaspar Maia @maialab.bsky.social · 29/04/2025
unleashtheshe.wordpress.com The #LabFunEpi joyfully participated in the Unleash the She fundraiser for ovarian cancer!
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Alexandre Gaspar Maia @maialab.bsky.social · 25/04/2025
25ml of water to celebrate the April 25th Portuguese Carnation Revolution!
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Alexandre Gaspar Maia @maialab.bsky.social · 24/04/2025
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Alexandre Gaspar Maia @maialab.bsky.social · 24/04/2025
Our search of a signature if persiter cells using open chromatin and expression with single cell resolution has started. Our paper is out as a pre-print: doi.org/101101/2025..... Work led by MD/PhD student @Mihai Dumbrava and postdoc @wazimismail.bsky.social, in collaboration with Kannan and Weroha.
doi.org
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Alexandre Gaspar Maia @maialab.bsky.social · 31/03/2025
@wazimismail.bsky.social presenting at the Keystone Symposia Epigenetics in Development and Disease.
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Alexandre Gaspar Maia @maialab.bsky.social · 22/03/2025
Great meeting in Antwerp to discuss novel sequencing technologies. #RNGS2025 #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 20/03/2025
Sequencing technologies meet Legoland. #RNGS2025 #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 20/03/2025
Great visit to ICBAS- Abel Salazar Institute of Biomedical Sciences to see the “new” building and to play a little part on the 50th anniversary. Thank you for the invitation Marta Amaro Santos. #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 13/03/2025
www.ocmfconference.com Save the date: Nov 10-11, 2025
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Alexandre Gaspar Maia @maialab.bsky.social · 08/03/2025
Marching for science!
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Reposted by Alexandre Gaspar Maia
Emil Lou, MD, PhD, FACP, FASCO @cancerassassin1.bsky.social · 03/03/2025
#StandUpForScience2025 in #Minnesota - information here, St. Paul, at the Minnesota State Capitol. Friday March 7. www.eventbrite.com/e/stand-up-f... #scienceforall #sciencenotsilence
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Alexandre Gaspar Maia @maialab.bsky.social · 25/02/2025
The MD/PhD student in our #LabFunEpi , Mihai Dumbrava has received an award from FWW! Thank you for the support.
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Alexandre Gaspar Maia @maialab.bsky.social · 14/02/2025
@wazimismail.bsky.social has been selected to present at the @keystonesymposia.bsky.social ! If you are around don’t miss his presentation. #LabFunEpi
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Reposted by Alexandre Gaspar Maia
Ronny Drapkin @rdrapkin8-penn.bsky.social · 24/01/2025
The Ovarian Cancer Research Syndicate schedule is out from the @pennmedicine.bsky.social Ovarian Cancer Research Center. Great line up!
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Alexandre Gaspar Maia @maialab.bsky.social · 09/01/2025
Happy New Year funny bunch! #LabFunEpi
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Alexandre Gaspar Maia @maialab.bsky.social · 14/12/2024
Happy Holidays from the #LabFunEpi.
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Alexandre Gaspar Maia @maialab.bsky.social · 07/12/2024
New lab “merch” for our holiday party!
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Alexandre Gaspar Maia @maialab.bsky.social · 05/12/2024
doi.org/10.1182/bloo... We are starting to understand the differences between TET2 and DNMT3A mutations at the molecular level and with single cell resolution. Incredible multiomic tour de force by @wazimismail.bsky.social , Jenna Fernandez, @moritzbinder.bsky.social , Mrinal Patnaik and many more.
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Alexandre Gaspar Maia @maialab.bsky.social · 23/11/2024
Great presentation by MD/PhD student Mihai Dumbrava to showcase our NIH/Mayo Ovarian SPORE pilot project to understand the immunosuppressive tumor microenvironment in ovarian cancer. #LabFunEpi #OvarianCancer
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Alexandre Gaspar Maia @maialab.bsky.social · 20/11/2024
Ovarian Cancer Midwest Focus conference: Flash Talk presentation first prize to my student @yiwenxie.bsky.social! Very sharp!
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Alexandre Gaspar Maia @maialab.bsky.social · 18/11/2024
The lab has recently turned 7th. I want to thank all the current and previous members of the laboratory of functional Epigenomics #LabFunEpi at Mayo Clinic.
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