Reposted by Madhusree SealBiohub @biohub.org · 11/06/2026In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible. bit.ly/4vK9LVn 15336 53
Reposted by Madhusree SealMark Peifer (He, him) @peiferlabunc.bsky.social · 06/01/2025At the heart of biology is the mantra: structure dictates function.Biological structures are also beautiful in their intricacy. David Goodsell brought this into public view. As he leaves "Molecule of the Month". here's a huge thank you for helping me see more clearly🧪1/2 cdn.rcsb.org/rcsb-pdb/gen... 511437 114
Reposted by Madhusree SealRCSB Protein Data Bank @rcsbpdb.bsky.social · 20/02/2025Want to learn more about Computed Structure Models? Visit PDB-101 to learn how AlphaFold2 models include a measure of reliability; how they have limitations; and how they can help determine experimental structures Great resource for the classroom pdb101.rcsb.org/lear... pdb101.rcsb.orgPDB101: Learn: Exploring Structural Biology with Computed Structure Models (CSMs)Computational methods like AlphaFold2 and RoseTTAFold2 use structures in the PDB archive to predict the folding of proteins. 054 5
Reposted by Madhusree SealcryoEM papers @cryoempapers.bsky.social · 24/01/2025Receptor binding, structure, and tissue tropism of cattle-infecting H5N1 avian influenza virus hemagglutinin pubmed.ncbi.nlm.nih.gov/39848246/ 021 2
Reposted by Madhusree SealcryoEM papers @cryoempapers.bsky.social · 31/01/2025Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan pubmed.ncbi.nlm.nih.gov/39884273/ #cryoEM 022 2