iiinova — where your digital self keeps evolving

Martin Grininger @m-grininger.bsky.social · 04/02/2026

With our research, we are one step closer to biotechnological palm oil alternatives 🌱 rdcu.be/e2nbH 📺📻 Featured on TV, radio, and online media, e.g.: www.tagesschau.de/inland/regio... #Sustainability #GreenBiotechnology #Biotechnology #SyntheticBiology #MetabolicEngineering #PalmOil #PalmOilFree

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Martin Grininger @m-grininger.bsky.social · 08/01/2026

Happy to have contributed to this issue! doi.org/10.1016/j.ti...

doi.org

Redirecting

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Martin Grininger @m-grininger.bsky.social · 08/01/2026

Short fatty acids, custom synthesized by engineered yeast 🧫 Here it is: doi.org/10.1038/s415... 🤝✨ Fantastic team effort — thanks to Yongjin Zhou! Science made possible at @goetheuni.bsky.social 🏛️🔬

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Martin Grininger @m-grininger.bsky.social · 26/11/2025

New in Angewandte 🔥: With two engineered changes, we reprogram mammalian fatty acid synthase to make pyrones instead of fatty acids! 🧬 Congrats Felix, Nadja & Caro! We delete the processing part + tweak the KS pocket, even mimicking PKS-like initiation. Paper: doi.org/10.1002/anie...

doi.org

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

A multienzyme was formed and evaluated by covalently linking 4-coumarate ligase (4CL1) from Piper methysticum to a non-reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP....

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Martin Grininger @m-grininger.bsky.social · 24/11/2025

Great meeting in Shenzhen by @asm.org and SIAT! Really appreciated the microbiology insights — amazing how central microbes are to so many of today’s challenges. @vscooper.micropopbio.org @rebeleinlab.bsky.social @helgebode.bsky.social @friedrich-group.bsky.social www.greeninger-chemistry.com/

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Reposted by Martin Grininger

Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · 11/11/2025

📝 Online now - the Review "Molecular mechanisms of the mammalian fatty acid cycle" from Christian Gusenda and @m-grininger.bsky.social. #FattyAcidBiosynthesis #FattyAcidSynthase #FAS #mFAS #AcylCarrierProtein #ACP Read it here 👉 authors.elsevier.com/sd/article/S...

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Martin Grininger @m-grininger.bsky.social · 10/05/2025

📣 Open call for a Full Professorship (W3) in Organic Synthesis. 🌍 University Frankfurt, Germany 🗓️ Application Deadline approaching: 23rd of May Join one of Germany’s leading universities. @goetheuni.bsky.social #ScienceCareers #JobOpportunity #FacultyPosition #OrganicChemistry

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Reposted by Martin Grininger

Stephan Lab @stephanlab.bsky.social · 02/05/2025

Excited to share my first post on Bluesky: I’ve recently been appointed as a Professor at Goethe University Frankfurt! 🎉 The Stephan Lab will use advanced bioimaging 🔬🧫 to explore how organelles collaborate to maintain subcellular architecture and metabolism.

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Martin Grininger @m-grininger.bsky.social · 23/04/2025

📢 The University of Frankfurt (Germany) is hiring a Full Professor in Organic Synthesis -->Cutting-edge research in an open, collaborative environment? Check out the call and join one of Germany’s leading research universities. #AcademicJobs #FacultyPosition www.nature.com/naturecareer...

nature.com

Professor (W3) in Organic Synthesis - Frankfurt am Main, Hessen (DE) job with Johann Wolfgang Goethe-Universität Frankfurt | 12838450

Goethe University Frankfurt am Main invites applications for the position of Professor (W3) in Organic Synthesis at the Faculty of Biochemistry, Ch...

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Martin Grininger @m-grininger.bsky.social · 23/04/2025

🚗💥 Henry Ford’s car assembly line is the perfect analogy for how nature builds polyketide natural compounds. But can we rearrange nature's assembly lines to make novel polyketides? 🔬 Recent breakthroughs are promising 📖 Read my perspective on how this vision is becoming reality. rdcu.be/ei12O

rdcu.be

Design principles imprinted by evolution

Nature Chemical Biology - Redesigning polyketide biosynthesis to either derivatize polyketides or develop new ones is highly desirable, but engineered pathways usually suffer from low product...

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