iiinova — where your digital self keeps evolving

L Brielmaier @lynnbr2.bsky.social · 07/10/2026

Greed, one of the seven deadly sins, will not go away.

L Brielmaier @lynnbr2.bsky.social · 07/10/2026

TDP-43 and ALS - what's wrong with my membranes? The membrane deformations observed in situations of TDP-43 misexpression strongly suggest a functional link between TDP-43 and membrane dynamics. www.sciencedirect.com/science/arti...

sciencedirect.com

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L Brielmaier @lynnbr2.bsky.social · 06/10/2026

The FBI Anti-Corruption Squad Was Circling Susan Collins — Until Trump Got in the Way Confession: The donor, an ex-defense contractor, told agents his company won millions in federal contracts by bankrolling campaigns of powerful politicians. www.propublica.org/article/fbi-...

propublica.org

The FBI Anti-Corruption Squad Was Circling Susan Collins — Until Trump Got in the Way

After the FBI caught a defense contractor’s CEO making illegal campaign contributions, it sought to launch a sweeping political bribery probe involving Collins and others. Then the second Trump admini...

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L Brielmaier @lynnbr2.bsky.social · 06/10/2026

This week's ALS research radar paints a dynamic picture, characterized by a rapid expansion of both fundamental scientific understanding and the therapeutic pipeline. als.arrovox.com/als

als.arrovox.com

Aperia | ALS

Weekly research briefing of recent ALS studies and findings for patients and families.

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L Brielmaier @lynnbr2.bsky.social · 06/10/2026

Last week’s poll results 57% PharmaVoice readers who think companies should continue disclosing phase 1 pipelines despite Eli Lilly’s decision to stop.

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L Brielmaier @lynnbr2.bsky.social · 05/10/2026

pills sink instead of float, just my luck

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Reposted by L Brielmaier

IEEE EMBS @embs.org · 05/10/2026

In a new #IEEE TNSRE study, researchers used remaining muscle signals from people with cervical #SpinalCordInjury to detect hand-movement intentions and control a robotic sixth finger. Read the paper: ieeexplore.ieee.org/document/116838…

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Reposted by L Brielmaier

Blue Dot in Red State @bluedotin.bsky.social · 05/10/2026

Great illustration.....best show this to Trump.

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Reposted by L Brielmaier

IEEE Spectrum @spectrum.ieee.org · 05/10/2026

The #NobelPrize for Medicine just went to the pioneers of optogenetics, a technique that lets scientists control neurons with light! Revisit our 2016 feature on the tiny wireless implants that brought this remarkable capability to freely moving lab mice: buff.ly/miuDBxC

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L Brielmaier @lynnbr2.bsky.social · 05/10/2026

The beginning and middle of the day as well. #EndALS

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L Brielmaier @lynnbr2.bsky.social · 05/10/2026

Oct. 19 Technical Assistance Webinar- RFA-NS-26-001: Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required) www.grants.gov/search-resul... Proposals due November 10th.

grants.gov

Lock

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L Brielmaier @lynnbr2.bsky.social · 04/10/2026

Their studies support further investigation of TBK1 augmentation as a therapeutic strategy for preventing disease caused by UBQLN2 mutations. TBK1 overexpression reduces neuronal loss in the P497S UBQLN2 mouse model of ALS/FTD. www.sciencedirect.com/science/arti...

sciencedirect.com

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L Brielmaier @lynnbr2.bsky.social · 03/10/2026

Researchers report early results from therapy designed for a single patient with a rare genetic form of ALS It speaks to the power of science and how far genetically targeted treatments have come. medicalxpress.com/news/2026-10...

medicalxpress.com

Researchers report early results from therapy designed for a single patient with a rare genetic form of ALS

Mayo Clinic researchers report encouraging early results from an experimental therapy targeting the genetic cause of a rare form of amyotrophic lateral sclerosis, or ALS.

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L Brielmaier @lynnbr2.bsky.social · 03/10/2026

All you need is love. But a little chocolate now and then doesn’t hurt.” — Charles M. Schulz

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L Brielmaier @lynnbr2.bsky.social · 02/10/2026

simply outperforming animal models is necessary but not sufficient. The adoption of Non-Animal Models will require changes in policy, training, and culture. spectrum.ieee.org/alternatives...

spectrum.ieee.org

Can New Technologies Finally Replace Animal Testing?

Changing habits may be the hardest engineering challenge of all

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L Brielmaier @lynnbr2.bsky.social · 02/10/2026

And when you ask 'em, "How much should we give?" Hoo, they only answer, "More, more, more, more" music.youtube.com/watch?v=r5Nz...

music.youtube.com

Fortunate Son

YouTube video by Creedence Clearwater Revival - Topic

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L Brielmaier @lynnbr2.bsky.social · 02/10/2026

I expect that on January 21st, The R's will return to screaming about The .

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Reposted by L Brielmaier

Bridging Voice @bridgingvoice.bsky.social · 02/10/2026

It's AAC Awareness Month—the perfect time to reshare our "What is AAC?" guide! AAC (Augmentative & Alternative Communication) is the collection of tools and strategies that help you communicate when speaking or using hands becomes difficult. It's at the heart of everything we do at Bridging Voice.

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L Brielmaier @lynnbr2.bsky.social · 02/10/2026

some patients with non-small-cell lung cancer who have surgery & start a targeted drug early, Dr. Herbst said, oncologists like himself now even dare to mouth the word “cure.” 34 %of patients with non-small-cell lung cancer never got a genetic test of their tumors. www.nytimes.com/2026/09/30/s...

nytimes.com

New Cancer Drugs Are Revolutionary. Why Don’t More Patients Get Them? (Gift Article)

Targeted gene therapies are highly effective at stopping cancers, but the very abundance of the treatments, plus cost and sluggish change, are hindering access.

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L Brielmaier @lynnbr2.bsky.social · 30/09/2026

New math The investigators evaluated 73 patients with motor neuron diseases, 120 patients with motor neuron diseases, and 38 healthy controls. Of the motor neuron disease patients, 4 had progressive muscular atrophy, 15 had primary lateral sclerosis, and 100 had amyotrophic lateral sclerosis.

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IEEE EMBS @embs.org · 30/09/2026

A new #IEEE TNSRE study shows how remaining muscle signals from people with cervical #SpinalCordInjury can reveal hand-movement intentions and control a robotic "sixth finger" for functional grasping tasks. ieeexplore.ieee.org/document/116838…

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Reposted by L Brielmaier

IEEE Spectrum @spectrum.ieee.org · 30/09/2026

MED-EL’s new implant puts the microphone, processor, and battery entirely beneath the skin, enabling users to hear while sleeping, swimming, and exercising.

spectrum.ieee.org

World’s First Fully Implanted Cochlear Implant Reaches Patients

Users get round-the-clock hearing with no visible external hardware

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L Brielmaier @lynnbr2.bsky.social · 30/09/2026

Meanwhile, the wryneck (Jynx torquilla), a relative of woodpeckers, holds the Guinness record for the longest bird tongue relative to body size. Its tongue is about two-thirds of its 16.5 cm (6.5 in) body length.

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Silverlark Media @silverlarkmedia.bsky.social · 30/09/2026

From my morning feed. 🙄

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L Brielmaier @lynnbr2.bsky.social · 30/09/2026

They provide free services via Bridging Voice to those with ALS! Founded in 2022, the company is known for generating ultra-realistic human voices and sound effects. www.msn.com/en-us/money/...

msn.com

MSN

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L Brielmaier @lynnbr2.bsky.social · 26/09/2026

“The more you can escape from how horrible things really are, the less it's going to bother you...and then, the worse things get.” ― Frank Zappa

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L Brielmaier @lynnbr2.bsky.social · 25/09/2026

On the Historic Results of the FUSION Trial for FUS-ALS. projectals.org/lori-hermsta... This is the second genetic ALS gene that has been reverse-engineered to create a functional therapy!

projectals.org

A Statement From Lori Hermstad: On the Historic Results of the FUSION Trial for FUS-ALS. | Project ALS

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L Brielmaier @lynnbr2.bsky.social · 24/09/2026

The diagnostic biomarker problem in amyotrophic lateral sclerosis: This Update distinguishes disease state biomarkers from diagnostic biomarkers; academic.oup.com/brain/advanc...

academic.oup.com

Validate User

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