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Lydia O'Sullivan

@lydiaosullivan.bsky.social
488 followers 560 following 4 posts

Radiotherapy, oncology, clinical trials methodology, evidence synthesis, HTA, outdoors, beaches, dogs. Research Associate at HRB-TMRN Views my own.

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Reposted by Lydia O'Sullivan
Andrew Dullea @andrewdullea.bsky.social · 01/07/2026
Our latest systematic review has just been published in Radiography - While data from prostate cancer studies suggest potential quality of life and toxicity improvements, comparative evidence across different cancers remains sparse and of very low certainty. www.radiographyonline.com/article/S107...
radiographyonline.com
Magnetic resonance guided radiotherapy (MRgRT) and clinical outcomes: A systematic review
Magnetic resonance-guided radiotherapy (MRgRT) offers potential advantages over conventional computed tomography-guided radiotherapy (CTgRT), however its impact on clinical outcomes remains unclear.
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Reposted by Lydia O'Sullivan
Leeds CTRU @leedsctru.bsky.social · 04/12/2025
⏳Don't miss out, early bird ends in 2 weeks! Join our 3-day Masterclass in the Design and Conduct of Complex Intervention Evaluations. Taking place across three days in the new year. ❗Limited spots are available so save your place now: lnkd.in/ekPieCFN
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Reposted by Lydia O'Sullivan
The Institute of Cancer Research @icr.ac.uk · 14/08/2025
Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation. To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️ www.icr.ac.uk/research-and...
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Marion Campbell @marionkcampbell.bsky.social · 18/08/2025
There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg  treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9 #MethodologyMonday #123
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Simon Gates @sim0ngates.bsky.social · 04/08/2025
I wrote some stuff about single-arm trials simonelgato.github.io/2025/06/10/s...
simonelgato.github.io
The Muddy Waters of single-arm trials
I’m a clinical trials statistician based at the Cancer Research UK Clinical Trials Unit, University of Birmingham, UK. I’m interested in Bayesian methods, adaptive trials, and generally questioning tr...
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STITCHES Medicine - the Best of Medical Research @medicine.stitches.today · 07/05/2025
The updated SPIRIT 2025 statement enhances randomized trial protocols, adding clarity and transparency for better research practices. by Chan AW, Boutron I (...) Hróbjartsson A et 36 al. in JAMA #MedSky 👉 get more here 📖 read the article:
jamanetwork.com
SPIRIT 2025 Statement
This Special Communication introduces the updated Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2025 statement, which includes substantive and structural changes to incorporate new evidence and emerging perspectives.
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Marita Hennessy @maritahennessy.bsky.social · 10/02/2025
Scoping reviews & their role in identifying research priorities H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans www.jclinepi.com/article/S089...
jclinepi.com
Scoping reviews and their role in identifying research priorities
Scoping reviews have been identified as appropriate methodologies to contribute to our knowledge. The objective of this review is to summarise how scoping reviews can be used to identify research prio...
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🐩 Poodle - Miniature @johnsonpham.bsky.social · 10/12/2024
That sounds like a perfect way to kick off the day! A cup of coffee always sets the right tone. ☕😊 #nicedogs #coffeedogs #nicedaywithdog
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Lydia O'Sullivan @lydiaosullivan.bsky.social · 21/01/2025
Great talk Darren, thanks again. Lots of tips for us to action! @andrewdullea.bsky.social
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The People's Review @thepeoplesreview.ie · 18/11/2024
Hello Bluesky 👋 #ThePeoplesReview is a citizen science project inviting the public to get involved in a systematic review about health! Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE
youtu.be
What is The People's Review?
YouTube video by The People's Review
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Dr Anne Littlewood @anne-infospec.bsky.social · 13/11/2024
Yet more evidence that including a librarian in an evidence synthesis project improves quality and reproducibility pmc.ncbi.nlm.nih.gov/articles/PMC... #medlibs #systematicreviews
pmc.ncbi.nlm.nih.gov
Effect of librarian collaboration on otolaryngology systematic review and meta-analysis quality
To determine if librarian collaboration was associated with improved database search quality, search reproducibility, and systematic review reporting in otolaryngology systematic reviews and meta-anal...
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Kerry Hood @kerryhood.bsky.social · 09/11/2024
How should we describe randomisation to people when recruiting them to a trial? Simple little study, but useful for us all to think about how we do this - it is not just understanding that is important, we also need to consider the acceptability of the language we use. rdcu.be/dZGg1
rdcu.be
Trial participants’ self-reported understanding of randomisation phrases in participation information leaflets can be high, but acceptability of some descriptions is low, especially those linked to ga...
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Darren Dahly @statsepi.bsky.social · 20/09/2024
Reflection paper on establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation. www.ema.europa.eu/en/establish...
ema.europa.eu
Establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation | European Medicines Agency (EMA)
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Carrie Price @carrieprice.bsky.social · 14/02/2024
Can I make another public service announcement, akin to the "don't ask your students to do systematic or scoping review but rather assign targeted activities that could help them perform one in the future?" A thread!
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