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Lukas Fiedler

@lukyfiedler.bsky.social
202 followers 381 following 12 posts

PhD student at ISTA, Swimmer, Auxin, Excited about cells and genomes, Cambridge Biochemistry BA & MSci 🏳️‍🌈🌱

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Reposted by Lukas Fiedler
Florent Waltz @florentwaltz.bsky.social · 3h
Huge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏 His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨ Proof that groundbreaking discoveries don't always come from animal models! 🔬
Chlamydomonas cells
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Lukas Fiedler @lukyfiedler.bsky.social · 03/10/2026
And here goes a parallel discovery from the Santiago-Frangos lab, taking a more general comparative genomics approach and digging into NO VEIN-Tiamat biochemistry!
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Lukas Fiedler @lukyfiedler.bsky.social · 03/10/2026
Fantastic discovery from @eiriklag.bsky.social and @galofir.bsky.social! Plants have a homolog of the bacterial counterphage system Tiamat called NO VEIN. When knocked down in tobacco, it shows a PVX viral multiplication phenotype!
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Reposted by Lukas Fiedler
Swiss National Science Foundation (SNSF) @snsf.ch · 22/09/2026
🏆 Biochemist Martin Jinek is the winner of the Swiss Science Prize #MarcelBenoist 2026, considered the Swiss #Nobel Prize. He contributed to the development of molecular scissors, namely CRISPR-Cas9 technology. Read more ➡️ sohub.io/3hs4
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Reposted by Lukas Fiedler
Nature Plants @natplants.nature.com · 08/09/2026
New Brief Communication: "Cell-based CRISPRa screen identifies a papillae-specific receptor kinase mediating broad-spectrum fungal resistance in rice" rdcu.be/ZZFv8dTuRi8a A RK that positively regulates fungal resistance via silicon-mediated physical & biochemical defences. #PlantScience
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Reposted by Lukas Fiedler
Dolf Weijers @dolfweijers.bsky.social · 23/07/2026
Online at @cellcellpress.bsky.social today: everything you always wanted (???) to know about Auxin Signaling and never dared to ask. From Jiashu, Aaron and Martijn in our team, with @luciastrader.bsky.social and Tongda Xu www.sciencedirect.com/science/arti...
sciencedirect.com
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Lukas Fiedler @lukyfiedler.bsky.social · 15/07/2026
Really enjoyed hearing about the creative process of the other young scientists in this episode! Thank you for featuring me @nightsciencepod.bsky.social @itaiyanai.bsky.social
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Reposted by Lukas Fiedler
Chung Hyun Cho @chc-evobio.bsky.social · 04/07/2026
Excited to share our new preprint led by Fred and me in collaboration with the archaeal community! We found that the molecular foundation of histone-based chromatin has pre-eukaryotic roots in Asgard archaea. (1/4) #ArchaeaSky www.biorxiv.org/content/10.6...
biorxiv.org
Emergence of histone-based chromatin complexity in Asgard archaea
The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...
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Reposted by Lukas Fiedler
Sorek Lab @soreklab.bsky.social · 17/06/2026
Preprint: Plant pathogens cleave 2’cADPR to suppress TIR immune signaling Inspired by knowledge on how phages inhibit bacterial immunity, we now show that disease-causing bacteria inhibit plant immunity in a similar way. A 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
Plant pathogens cleave 2'cADPR to suppress TIR immune signaling
Small molecules produced by TIR (Toll-interleukin-1 receptor) domains are essential for plant immune signaling. A central TIR-derived signal is 2'cADPR, a cyclic ADP-ribose (ADPR) molecule that is gen...
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Reposted by Lukas Fiedler
Hiro Nakagami @grandpahiro.bsky.social · 09/06/2026
Here is our contribution to this lovely special issue. Together with talented PhD students Gabriel and Mung Hsia, we discussed when and how pattern-triggered immunity had been established in plants. doi.org/10.1016/j.cu... @watertoland.bsky.social @mpipz.bsky.social
doi.org
Redirecting
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Reposted by Lukas Fiedler
Marion Clavel @thevirusmc.bsky.social · 29/05/2026
Our work is out now! (www.science.org/doi/10.1126/...). We discover a selective autophagy pathway that protects plants from the mess caused by RNA viruses. Intrigued? Follow the spaghetti trail for a summary of our findings🧵-->
science.org
Selective autophagy fine-tunes plant immunity to promote cell survival during viral infection
RNA viruses co-opt host endomembranes to form replication complexes, often triggering cellular stress and immune responses. Here, we show that Arabidopsis thaliana activates selective autophagy to res...
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Reposted by Lukas Fiedler
Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · 14/05/2026
It's out! 🥳 In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET. 📝 Paper: www.nature.com/articles/s41... 🧵 Thread: bsky.app/profile/madi... #teamtomo #proteomics #AlphaFold
nature.com
In situ architecture of plasmodesmata in Physcomitrium patens resolved by cryo-electron tomography - Nature Plants
Using cryo-electron tomography, the authors reveal how plasmodesmata (plant cytoplasmic bridges) are gated by cell wall remodelling and how helical protein assemblies scaffold internal membranes, with...
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Reposted by Lukas Fiedler
Michael Borg @borglab.bsky.social · 02/04/2026
Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...
Undaria pinnatifida gametophyte
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Thibaut Brunet @thibautbrunet.bsky.social · 28/02/2026
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)
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New Phytologist @newphyt.bsky.social · 12/02/2026
Masters of perception: phosphorylation-dependent signaling in plants #TansleyInsight by Roosjen et al. nph.onlinelibrary.wiley.com/doi/10.1111/... #plantscience
Integrative proteomics approaches for data-driven reconstruction of kinase signaling.
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Zak Swartz @zakswartz.bsky.social · 07/02/2026
Destigmatize getting things wrong sometimes! Science can gracefully self-correct if we allow it. Well done all around. The cteno vs. sponge saga continues...
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Reposted by Lukas Fiedler
Marco Incarbone @incavirus.bsky.social · 02/12/2025
Preprint alert! It is my great pleasure to announce the first manuscript from the lab, a story that started @gmivienna.bsky.social and was mainly accomplished by the intrepid @gesahoffmann.bsky.social at @mpi-mp-potsdam.bsky.social. A brief thread with our findings www.biorxiv.org/content/10.1...
biorxiv.org
AGO5 restricts virus vertical transmission in plant gametophytes
The propagation of a viral infection from a host parent to its progeny is known as vertical transmission, or seed transmission in plants. It allows viral infections to rapidly spread locally via polle...
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Lukas Fiedler @lukyfiedler.bsky.social · 16/11/2025
Wow!! And I naively thought that the 2023 synteny paper supporting ctenophores already settled the dust...
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Yasin Dagdas @plantophagy.bsky.social · 31/10/2025
This Halloween, we have a spooky evolutionary story for you. The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41... Here’s why I love this work — and why I think you’ll enjoy it too. 👇
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Lukas Fiedler @lukyfiedler.bsky.social · 02/10/2025
Previously on BioRxiv, and now a final version of our paper is out! What a great lesson in plant self-organization: Auxin targets its own transporter through a cell-surface kinase complex in a positive feedback loop www.cell.com/cell/fulltex...
cell.com
ABP1/ABL3-TMK1 cell-surface auxin signaling targets PIN2-mediated auxin fluxes for root gravitropism
In gravistimulated roots, gravity perception in the columella redirects the flow of the plant hormone auxin toward the lower root side, where it inhibits cell elongation for downward root bending. Thi...
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Christian Fankhauser @chfankhauser.bsky.social · 26/06/2025
Remarkable paper explaining how sea slugs maintain chloroplasts obtained by kleptoplasty active for many month & eventually digest them for resources www.cell.com/cell/fulltex...
cell.com
A host organelle integrates stolen chloroplasts for animal photosynthesis
Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.
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Itai Yanai @itaiyanai.bsky.social · 16/06/2025
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
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Lukas Fiedler @lukyfiedler.bsky.social · 13/06/2025
Well-deserved ice-cream after canoeing from #TCTeAC!
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Ben Hartl @bhartl.bsky.social · 12/06/2025
science is magic #TCTeAC
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Damir Baranasic @da-bar.bsky.social · 11/06/2025
#TCTeAC right now!
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Lukas Fiedler @lukyfiedler.bsky.social · 11/06/2025
Go flower design go!!! #TCTeAC @nickdesnoyer.bsky.social
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Lukas Fiedler @lukyfiedler.bsky.social · 10/06/2025
If you want to improvise the dance moves to just about any song, pretend you are doing laundry, it's very easy
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