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Luke O’Shea

@lukeoshea.bsky.social
1.9K followers 87 following 76 posts

Director of Innovation, University College London Hospitals. Views my own

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Luke O’Shea @lukeoshea.bsky.social · 25/06/2026
Loved doing keynote at Climate and Health summit at #Earthfest 2026. Timing poignant given current heat wave, but the energy around action was uplifting despite the challenges we all face in driving change forward. #ClimateAction
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Luke O’Shea @lukeoshea.bsky.social · 30/05/2026
www.theguardian.com/society/2026...
theguardian.com
Groundbreaking genomic test could spare millions of breast cancer patients chemotherapy
Trial suggests patients with a low test score could be treated with hormone therapy alone with near-identical outcomes
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Luke O’Shea @lukeoshea.bsky.social · 18/02/2026
Baduism is still great
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Luke O’Shea @lukeoshea.bsky.social · 16/02/2026
Excellent news
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Luke O’Shea @lukeoshea.bsky.social · 14/01/2026
Lest we forget the greatest global challenge we all are facing...
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Luke O’Shea @lukeoshea.bsky.social · 14/01/2026
Good news! Do you know how much they were aiming to secure at the auction? How do the prices compare to previous auctions? Great journalism. I love your work
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Luke O’Shea @lukeoshea.bsky.social · 08/01/2026
Life saving/extending drug approved for bowel cancer patients thanks to biosimilar re-appraisal after £££ branded drug rejected. I lobbied NICE for over 2 years & they listened! Bevacizumab is the START. More biosimilars/generics should now follow www.nice.org.uk/news/article...
nice.org.uk
Thousands more people with advanced bowel cancer to benefit as NICE approves bevacizumab biosimilars
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Luke O’Shea @lukeoshea.bsky.social · 20/12/2025
Ian Beales' easy peels? Or Ian Bealers, wheeler dealer, easy peelers? I think those are the two main options
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Luke O’Shea @lukeoshea.bsky.social · 19/12/2025
You dont sound hungover. It's really good. I recently recorded this pod with ex BBC foreign correspondent and film maker Martin Sixsmith and I was also quite hungover. Martin did exactly the same course as you btw. We talk Russia in case you want to reminisce. harknessfellows.org.uk/podcasts/luk...
harknessfellows.org.uk
Luke O’Shea & Martin Sixsmith - Harkness Fellows
Despite fellowships more than thirty years apart and on opposite sides of the USA, Luke and Martin find they have much in common. From school drills for security, through living in communist countries...
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Luke O’Shea @lukeoshea.bsky.social · 19/12/2025
Love this
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Luke O’Shea @lukeoshea.bsky.social · 12/12/2025
The ‘super flu’ idea is spreading fast, but the actual flu is following normal trends so far if slightly earlier. Good analysis David anyway
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Luke O’Shea @lukeoshea.bsky.social · 12/12/2025
Deja Flu is very good. Chapeau
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Luke O’Shea @lukeoshea.bsky.social · 09/12/2025
We also talk about the book, Oscar nominated film and the lovely person who is Philomena (played by Judy Dench in the film, here with Steve Coogan playing Martin). Amazing story, film and impact in bringing light to the forced adoption scandal in Ireland
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Luke O’Shea @lukeoshea.bsky.social · 09/12/2025
NEW Podcast Out - My chat with legendary BBC foreign correspondent & film maker, Martin Sixsmith. Found lots in common - living behind Iron Curtain, US @commonwealthfund.org fellowship, working in government, storytelling & making sense of a divided world harknessfellows.org.uk/podcasts/luk...
harknessfellows.org.uk
Luke O’Shea & Martin Sixsmith - Harkness Fellows
Despite fellowships more than thirty years apart and on opposite sides of the USA, Luke and Martin find they have much in common. From school drills for security, through living in communist countries...
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Luke O’Shea @lukeoshea.bsky.social · 30/11/2025
He's a lucky guy. 😊
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Luke O’Shea @lukeoshea.bsky.social · 28/11/2025
Great meeting staff on the wards and in theatres today & talking sustainability. We’ve spoken to 450 staff across UCLH this month about improving hand hygiene and reducing glove use. Better for patients, better for the planet and saves money too.
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Luke O’Shea @lukeoshea.bsky.social · 19/11/2025
I don't know what the ultimate carrot is, but I do know that it's not Chanteney. Metaphorically pointless(though technically they have a point of sorts)
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Luke O’Shea @lukeoshea.bsky.social · 18/11/2025
Guy next to me on eurostar watching this. No sound & I was reading as well, but I was invested in strange family relationship. He is 2/3 goof, 1/3 armed robber. Missed last section as arrived in London, so assume tatum, dunst & kids all get new identities and move abroad or something?
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Luke O’Shea @lukeoshea.bsky.social · 15/11/2025
Visited Hospital de Sant Pau. Breathtaking art nouveau hospital in Barcelona. Incredible and window into 1920s medicine and earliest net zero hospital, powered on geothermal from 400 wells each 100 deep. Wow
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Luke O’Shea @lukeoshea.bsky.social · 13/11/2025
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Luke O’Shea @lukeoshea.bsky.social · 13/11/2025
On a 285 km/hr train to Barcelona for a health conference where am speaking about innovation and also climate action. Wonderful experience, comfy, fast WIFI, good catering. So much nicer than flying! Just over £46 each way. So much cheaper than UK trains too!
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Luke O’Shea @lukeoshea.bsky.social · 06/11/2025
Great to speak at #KFAnnual Conf on climate & our work @uclh. Serious stuff but there is hope, as we have the solutions. Good climate strategy does not run against finance, tech or quality, but harnesses them. The NHS can lead the world in this & build green economic growth @thekingsfund.bsky.social
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Luke O’Shea @lukeoshea.bsky.social · 03/11/2025
This line up also works for the new Great British Celebrity Macramé tie down series I'm pitching to channel 5, but I would add in Peter Andre
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Luke O’Shea @lukeoshea.bsky.social · 24/10/2025
CAR-T cell therapy is one of the biggest breakthrough cancer treatments in recent years. Proud that @uclh is trialing its use for multiple sclerosis for the first time. Extraordinary science and fascinating development for autoimmune conditions gbr01.safelinks.protection.outlook.com?url=https%3A...
gbr01.safelinks.protection.outlook.com
Woman has new multiple sclerosis treatment that doctors say could be 'game-changer'
Doctors are looking to recruit more people for the trial, which they say could one day be given as a single one-off treatment.
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Luke O’Shea @lukeoshea.bsky.social · 17/10/2025
Thanks Alf. I need to pull it all together. I’d love to say hello at some point soon
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Luke O’Shea @lukeoshea.bsky.social · 17/10/2025
Exhausted but elated after incredible week rethinking clinic letters for the modern era. Brought GPs, @uclh staff, patients together for a huge push. The time, safety challenges, cost & impact on GP & hospital staff is vast. Got down to 9 key solutions, 1 worked up prototype & we’re done ✔️
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Luke O’Shea @lukeoshea.bsky.social · 15/10/2025
Actually a really fascinating article. We need to the great British values of the middle ages. Thanks Andy
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Luke O’Shea @lukeoshea.bsky.social · 14/10/2025
Not published yet, but would like to. Will update here when I do. Housing is an interesting one…
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Luke O’Shea @lukeoshea.bsky.social · 14/10/2025
I'd love to talk to you about this and the whole set of problems for patients that has come out of our research. A fundamental issue is the letter has at least 4 audiences 1)patients/families 2)GP 3)core hospital note 4) to future self for next consult. It fails on most
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Luke O’Shea @lukeoshea.bsky.social · 13/10/2025
Excited to start our clinic letter sprint today with patients, GPs, @uclh clinicians, techies and administrators. Letters have a massive role, safety critical, hugely expensive and time consuming. Major challenges outlined today, so looking forward to what we can do about it
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Luke O’Shea @lukeoshea.bsky.social · 12/10/2025
This is partly why it felt revolutionary when record shops introduced listening stations, albeit only particular albums. Imagine being able to listen to it before you bought it? Or being able to return it if you didn't like it. No, usually the only option was really to get your mate to buy it first
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Luke O’Shea @lukeoshea.bsky.social · 12/10/2025
The delicate parasol of the Pleated Inkcap. This fragile fungi lives for only 24 hours. Nature is amazing. Let's protect it
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Luke O’Shea @lukeoshea.bsky.social · 09/10/2025
Big role in Arab Spring of course, though many uprisings were not successful (apart from Tunisia) and lordy there has been some horrible violence and displacement. All in all you are winning hands down
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Luke O’Shea @lukeoshea.bsky.social · 09/10/2025
That's pretty damn amazing I'd say. Hope all well Marie
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Luke O’Shea @lukeoshea.bsky.social · 01/10/2025
On wards today at uclh - remarkable clinical skills & v complex patients. ⬆️ role for generalists - Ward round strategy key, but not standardised - many reasons for discharge delays - disposable curtains are v hard to draw - scrubs pockets are too small &📱falls out
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Luke O’Shea @lukeoshea.bsky.social · 25/09/2025
Stunning news from UCLH on this incredible Huntington’s disease breakthrough. Nice to see some evidence based positive medical news! www.uclh.nhs.uk/news/hunting...
uclh.nhs.uk
Huntington’s Disease gene therapy shows 75 per cent slowing of disease
A new gene therapy to treat Huntington’s disease has shown positive data from the study of AMT-130 which is being run at UCLH and other sites.
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Luke O’Shea @lukeoshea.bsky.social · 03/09/2025
Rain and shine in Paddington
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Luke O’Shea @lukeoshea.bsky.social · 23/08/2025
Watching a merganser fishing in France. Nature is incredible. Let's protect it.
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Luke O’Shea @lukeoshea.bsky.social · 05/08/2025
Important to spread hope. People are now putting up a gigawatt’s worth of solar panels, the rough equivalent of the power generated by one coal-fired plant, every fifteen hours… www.newyorker.com/news/annals-...
newyorker.com
4.6 Billion Years On, the Sun Is Having a Moment
In the past two years, without much notice, solar power has begun to truly transform the world’s energy system.
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Luke O’Shea @lukeoshea.bsky.social · 26/07/2025
Thanks for doing this important and brilliantly informative podcast, and shining a light on OCD as a devastatingly difficult and misunderstood condition. It's truly appreciated
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Luke O’Shea @lukeoshea.bsky.social · 23/06/2025
The rise of YouTube shorts in the last year is mind blowing. Up to 200 billion daily views or over 1 billion hrs a day. In a world of 8 bn people! Will any productivity gains from AI simply be offset by increasingly effective tech distractions? www.thewrap.com/youtube-shor...
thewrap.com
YouTube Shorts Now Averages 200 Billion Daily Views
YouTube Shorts now averages 200 billion daily views, CEO Neal Mohan announced during his keynote at Cannes Lions 2025.
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Luke O’Shea @lukeoshea.bsky.social · 14/06/2025
Watching the bbc pulp Live Session reminded me how funny his lyrics are. Even new stuff like Dishes (I’m not Jesus though I have the same initials, I’m the man who stays home & does the dishes).That misshapes verse is genius. We’ll use the one thing we’ve got more of - that’s cheese rinds (surely?)
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Luke O’Shea @lukeoshea.bsky.social · 09/06/2025
Worked with Axel at Prime Minister's strategy unit under Blair. Very smart.
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Luke O’Shea @lukeoshea.bsky.social · 06/06/2025
Also lots of gym folks have gone vegan to get the perfect gym body. Foxes been watching gamechangersmovie.com
gamechangersmovie.com
The Game Changers Official Film Website | Documentary
Watch the Game Changers movie about plant-based eating, protein, and strength. Presented by James Cameron, Arnold Schwarzenegger, Jackie Chan, Lewis Hamilton, Novak Djokovic and Chris Paul.
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Luke O’Shea @lukeoshea.bsky.social · 03/06/2025
Great #FestivalofExcellence hearing superb improvement work UCLH. I talked about quality, & why spending more ≠ better outcomes. Gave 3 case studies which show drive quality ⬆️ then cost ⬇️ (hip surgery, gloves off, clinic letters). Complexity the enemy of reliability & quality
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Luke O’Shea @lukeoshea.bsky.social · 17/05/2025
That's so good to hear Helen!
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Luke O’Shea @lukeoshea.bsky.social · 17/05/2025
Person centred care at it's best! Uclh team working across services to enable one of our young, severely needle phobic patients to get the vaccinations needed to visit his family abroad for the first time. (Spoiler alert: solution was to vax when under general for his dental work) buff.ly/pFxkkcj
buff.ly
Autistic teen with needle phobia helped to go abroad by NHS
Terence Panzu-Lema is given the ability to travel abroad for the first time, by a unique collaboration by NHS teams.
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Luke O’Shea @lukeoshea.bsky.social · 16/05/2025
By the way our uclh sustainability transformation fund applications need to be in by the 26th. If you have an idea for greening ID, we want to hear it! Email me if want to speak. Application easy. Funds for two years
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Luke O’Shea @lukeoshea.bsky.social · 16/05/2025
What China is doing on Solar PV, batteries & cars is mind blowing. Still need massive push in other areas like chemicals though in China. Follow @hannahritchie.bsky.social if you don't know her. Superb and data driven analysis
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Luke O’Shea @lukeoshea.bsky.social · 15/05/2025
BIG STORY which brings hope! China's emissions are dropping for the first time! This really matters as China has more than a third of global emissions. Wow. www.carbonbrief.org/analysis-cle... Climate action on a massive scale
carbonbrief.org
Analysis: Clean energy just put China’s CO2 emissions into reverse for first time - Carbon Brief
For the first time, the growth in China’s clean power generation has caused the nation’s carbon dioxide (CO2) emissions to fall despite rapid power demand growth.
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