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Luke O’Shea

@lukeoshea.bsky.social
1.9K followers 87 following 76 posts

Director of Innovation, University College London Hospitals. Views my own

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Luke O’Shea @lukeoshea.bsky.social · 25/06/2026
Loved doing keynote at Climate and Health summit at #Earthfest 2026. Timing poignant given current heat wave, but the energy around action was uplifting despite the challenges we all face in driving change forward. #ClimateAction
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Luke O’Shea @lukeoshea.bsky.social · 30/05/2026
www.theguardian.com/society/2026...
theguardian.com
Groundbreaking genomic test could spare millions of breast cancer patients chemotherapy
Trial suggests patients with a low test score could be treated with hormone therapy alone with near-identical outcomes
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Luke O’Shea @lukeoshea.bsky.social · 14/01/2026
Lest we forget the greatest global challenge we all are facing...
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Luke O’Shea @lukeoshea.bsky.social · 08/01/2026
Life saving/extending drug approved for bowel cancer patients thanks to biosimilar re-appraisal after £££ branded drug rejected. I lobbied NICE for over 2 years & they listened! Bevacizumab is the START. More biosimilars/generics should now follow www.nice.org.uk/news/article...
nice.org.uk
Thousands more people with advanced bowel cancer to benefit as NICE approves bevacizumab biosimilars
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Luke O’Shea @lukeoshea.bsky.social · 09/12/2025
NEW Podcast Out - My chat with legendary BBC foreign correspondent & film maker, Martin Sixsmith. Found lots in common - living behind Iron Curtain, US @commonwealthfund.org fellowship, working in government, storytelling & making sense of a divided world harknessfellows.org.uk/podcasts/luk...
harknessfellows.org.uk
Luke O’Shea & Martin Sixsmith - Harkness Fellows
Despite fellowships more than thirty years apart and on opposite sides of the USA, Luke and Martin find they have much in common. From school drills for security, through living in communist countries...
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Luke O’Shea @lukeoshea.bsky.social · 28/11/2025
Great meeting staff on the wards and in theatres today & talking sustainability. We’ve spoken to 450 staff across UCLH this month about improving hand hygiene and reducing glove use. Better for patients, better for the planet and saves money too.
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Luke O’Shea @lukeoshea.bsky.social · 15/11/2025
Visited Hospital de Sant Pau. Breathtaking art nouveau hospital in Barcelona. Incredible and window into 1920s medicine and earliest net zero hospital, powered on geothermal from 400 wells each 100 deep. Wow
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Luke O’Shea @lukeoshea.bsky.social · 13/11/2025
On a 285 km/hr train to Barcelona for a health conference where am speaking about innovation and also climate action. Wonderful experience, comfy, fast WIFI, good catering. So much nicer than flying! Just over £46 each way. So much cheaper than UK trains too!
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Luke O’Shea @lukeoshea.bsky.social · 06/11/2025
Great to speak at #KFAnnual Conf on climate & our work @uclh. Serious stuff but there is hope, as we have the solutions. Good climate strategy does not run against finance, tech or quality, but harnesses them. The NHS can lead the world in this & build green economic growth @thekingsfund.bsky.social
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Luke O’Shea @lukeoshea.bsky.social · 24/10/2025
CAR-T cell therapy is one of the biggest breakthrough cancer treatments in recent years. Proud that @uclh is trialing its use for multiple sclerosis for the first time. Extraordinary science and fascinating development for autoimmune conditions gbr01.safelinks.protection.outlook.com?url=https%3A...
gbr01.safelinks.protection.outlook.com
Woman has new multiple sclerosis treatment that doctors say could be 'game-changer'
Doctors are looking to recruit more people for the trial, which they say could one day be given as a single one-off treatment.
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Luke O’Shea @lukeoshea.bsky.social · 17/10/2025
Exhausted but elated after incredible week rethinking clinic letters for the modern era. Brought GPs, @uclh staff, patients together for a huge push. The time, safety challenges, cost & impact on GP & hospital staff is vast. Got down to 9 key solutions, 1 worked up prototype & we’re done ✔️
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Luke O’Shea @lukeoshea.bsky.social · 13/10/2025
Excited to start our clinic letter sprint today with patients, GPs, @uclh clinicians, techies and administrators. Letters have a massive role, safety critical, hugely expensive and time consuming. Major challenges outlined today, so looking forward to what we can do about it
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Luke O’Shea @lukeoshea.bsky.social · 12/10/2025
The delicate parasol of the Pleated Inkcap. This fragile fungi lives for only 24 hours. Nature is amazing. Let's protect it
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Luke O’Shea @lukeoshea.bsky.social · 01/10/2025
On wards today at uclh - remarkable clinical skills & v complex patients. ⬆️ role for generalists - Ward round strategy key, but not standardised - many reasons for discharge delays - disposable curtains are v hard to draw - scrubs pockets are too small &📱falls out
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Luke O’Shea @lukeoshea.bsky.social · 25/09/2025
Stunning news from UCLH on this incredible Huntington’s disease breakthrough. Nice to see some evidence based positive medical news! www.uclh.nhs.uk/news/hunting...
uclh.nhs.uk
Huntington’s Disease gene therapy shows 75 per cent slowing of disease
A new gene therapy to treat Huntington’s disease has shown positive data from the study of AMT-130 which is being run at UCLH and other sites.
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Luke O’Shea @lukeoshea.bsky.social · 03/09/2025
Rain and shine in Paddington
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Luke O’Shea @lukeoshea.bsky.social · 23/08/2025
Watching a merganser fishing in France. Nature is incredible. Let's protect it.
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Luke O’Shea @lukeoshea.bsky.social · 05/08/2025
Important to spread hope. People are now putting up a gigawatt’s worth of solar panels, the rough equivalent of the power generated by one coal-fired plant, every fifteen hours… www.newyorker.com/news/annals-...
newyorker.com
4.6 Billion Years On, the Sun Is Having a Moment
In the past two years, without much notice, solar power has begun to truly transform the world’s energy system.
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Luke O’Shea @lukeoshea.bsky.social · 23/06/2025
The rise of YouTube shorts in the last year is mind blowing. Up to 200 billion daily views or over 1 billion hrs a day. In a world of 8 bn people! Will any productivity gains from AI simply be offset by increasingly effective tech distractions? www.thewrap.com/youtube-shor...
thewrap.com
YouTube Shorts Now Averages 200 Billion Daily Views
YouTube Shorts now averages 200 billion daily views, CEO Neal Mohan announced during his keynote at Cannes Lions 2025.
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Luke O’Shea @lukeoshea.bsky.social · 03/06/2025
Great #FestivalofExcellence hearing superb improvement work UCLH. I talked about quality, & why spending more ≠ better outcomes. Gave 3 case studies which show drive quality ⬆️ then cost ⬇️ (hip surgery, gloves off, clinic letters). Complexity the enemy of reliability & quality
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Luke O’Shea @lukeoshea.bsky.social · 17/05/2025
Person centred care at it's best! Uclh team working across services to enable one of our young, severely needle phobic patients to get the vaccinations needed to visit his family abroad for the first time. (Spoiler alert: solution was to vax when under general for his dental work) buff.ly/pFxkkcj
buff.ly
Autistic teen with needle phobia helped to go abroad by NHS
Terence Panzu-Lema is given the ability to travel abroad for the first time, by a unique collaboration by NHS teams.
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Luke O’Shea @lukeoshea.bsky.social · 15/05/2025
BIG STORY which brings hope! China's emissions are dropping for the first time! This really matters as China has more than a third of global emissions. Wow. www.carbonbrief.org/analysis-cle... Climate action on a massive scale
carbonbrief.org
Analysis: Clean energy just put China’s CO2 emissions into reverse for first time - Carbon Brief
For the first time, the growth in China’s clean power generation has caused the nation’s carbon dioxide (CO2) emissions to fall despite rapid power demand growth.
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Luke O’Shea @lukeoshea.bsky.social · 24/04/2025
It’s quite incredible what UCLH staff do for our patients. Take outpatients, where last year we did over 1.4m appointments up about 100k on the year before. Some weeks we saw 30,000 patients. The NHS is under huge pressure but the work of our staff is just remarkable
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Luke O’Shea @lukeoshea.bsky.social · 20/03/2025
Great to have the Chinese Health Minister come to see first-hand what we are doing at UCLH on sustainability. The Chinese Government is responsible for the largest hospital sector in the world, so discussing net zero is important. Minister was full of praise for our staff’s work
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Luke O’Shea @lukeoshea.bsky.social · 06/03/2025
Oxford sparkling tonight
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Luke O’Shea @lukeoshea.bsky.social · 05/03/2025
Sat in on a superb UCLH ENT clinic today trialing ambient AI to write notes/letters - patients & clinicians happy - shifts doc from writer to proof reader - saves time but justifies £? - incredibly complex case worked well - no idea why send letters every time, even if AI helps
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Luke O’Shea @lukeoshea.bsky.social · 25/02/2025
Loved speaking on electronic health records, including on critical need to focus on adoption, that digitisation in itself does not guarantee transformation and the implications of hardwiring EHRs into so much of what we do. Great debate.
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Reposted by Luke O’Shea
Shelford Group @shelfordgroup.bsky.social · 25/02/2025
Brilliant discussion with colleagues from @ouhospitals.bsky.social @cuhnhs.bsky.social @microsoft.com and @lukeoshea.bsky.social and @nellthornton.bsky.social about the role of AI in delivering improved healthcare, including the trade-offs we need to discuss with the public #Shelford2025
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Luke O’Shea @lukeoshea.bsky.social · 10/01/2025
As the most destructive wildfires in US history rage, the climate stats have dropped 2024 was the hottest year on record, the first above 1.5C We may be the only civilised life anywhere in the universe Time is running out Millions of us need to act Thank you if you are
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Luke O’Shea @lukeoshea.bsky.social · 10/12/2024
Over 200,000 trees planted since we switched to Ecosia as our default search engine at uclh! Plants a tree for every 45 searches & is carbon negative. Easy to do, great search algorithm & climate friendly. Who else will follow?
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Luke O’Shea @lukeoshea.bsky.social · 06/12/2024
Visited Toyota factory & 🤯 - 🚗 every 1-2 mins - drive quality ⬆️ waste/cost ⬇️ - Mgmt system crystal clear (planning to delivery). Qual control every step - STANDARDISE EVERYTHING incl. jobs & work processes. Staff follow to letter - relentless improvement by workers & reward
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Luke O’Shea @lukeoshea.bsky.social · 29/11/2024
We win Nobel Prizes for AI in the UK. It has jaw dropping capabilities in health. We have burgeoning patient need. So why is the NHS seemingly impenetrable to AI’s advances? My HSJ article here hsj.cdn.wilmingtonplc.com/2024/10/23/h...
hsj.cdn.wilmingtonplc.com
How to bridge the NHS’s gulf on AI adoption
AI is shaping many aspects of our lives, yet the NHS is seemingly impenetrable to its advances – here’s how to close the gulf between policy and implementation
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Luke O’Shea @lukeoshea.bsky.social · 29/11/2023
Hancock’s up this week at the Inquiry. I keep thinking about a guy who died on the wards. Caught Covid the day before restrictions came in. Delay cost lives. But the lessons are wider. And the parallels with the climate crisis are striking www.hsj.co.uk/delay-cost-l...
hsj.co.uk
Delay cost lives during the pandemic, let's not repeat that ...
Covid's harsh lessons underscore the urgency for NHS-led climate action, emphasising efficiency, innovation, and immediate intervention to protect lives and the planet, writes Luke O'Shea
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Luke O’Shea @lukeoshea.bsky.social · 28/11/2023
My new HSJ article is just out. “Delay cost lives during the pandemic, let's not repeat that mistake with climate change” Reflecting on the Covid Inquiry, the parallels with Climate are striking www.hsj.co.uk/delay-cost-l...
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Luke O’Shea @lukeoshea.bsky.social · 08/11/2023
Over 100,000 trees planted since we switched to Ecosia as our default search engine at UCLH!Plants a tree for every 45 searches & is carbon negative. Easy to do, great search algorithm & climate friendly. Which other trusts else will follow?
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Luke O’Shea @lukeoshea.bsky.social · 02/11/2023
#CovidInquiry rightly charting the awful failure to act decisively, despite what we saw in our hospitals & the obvious path of the virus. Recent global temperatures have been extraordinary, with records set every month & by large margins The time to act is now #ClimateCrisis
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Luke O’Shea @lukeoshea.bsky.social · 23/10/2023
Isn't nature amazing
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Luke O’Shea @lukeoshea.bsky.social · 19/10/2023
Impressed by MS CEO, Satya Nadella’s vision around the bottom up democratisation of AI & taking the time to talk to us in the NHS about our challenges. He parallels AI impact and risks with the Industrial Revolution, which is fair, but the exponential speed of change makes this different
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