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John B. Cole

@lsmsa1990.bsky.social
793 followers 2.6K following 1.6K posts

Dairy cattle geneticist, mediocre Python programmer, eccentric cat gentleman, Irish bouzouki owner, LSMSA, LSU, AAAS Fellow.

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John B. Cole @lsmsa1990.bsky.social · 05/10/2026
There are scarier bridges in Maryland.
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John B. Cole @lsmsa1990.bsky.social · 05/10/2026
I work with dairy cows, so.
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John Fugelsang @johnfugelsang.bsky.social · 05/10/2026
This is how the new CBS keeps people from remembering that the longest serving GOP Speaker of the House ultimately went to jail for covering up child rape. Which is apparently always in season.
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John Scalzi @scalzi.com · 05/10/2026
This is your occasional reminder that generative "AI" in particular could have been developed on public domain materials and/or licensed and compensated works but the major players intentionally, methodically and systemically chose to steal labor from working creative folks instead
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Prisonculture @prisonculture.bsky.social · 01/10/2026
"The MAGA right must be defeated, not negotiated with."
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John B. Cole @lsmsa1990.bsky.social · 01/10/2026
Brooke Rollins made an appearance at World Dairy Expo yesterday. I refused to attend her talk on principle, but I'm told the room was full when she started and nearly empty when she finished. If the regime is losing dairy farmer support, well, that doesn't bode well for Rs in November.
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Dilek Sayedahmed @dileksayedahmed.bsky.social · 19/09/2026
I truly, deeply, sincerely do think the guy flipping burgers at McDonalds should be able to afford rent, bills, and groceries with his paycheck alone. That's kind of the whole point of having a job and I can't believe this is considered a radical position.🤷🏽‍♀️
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John B. Cole @lsmsa1990.bsky.social · 01/10/2026
Why can't the replicator use a combination of his voiceprint and comm badge proximity to figure out it's the Captain asking and give him tea, Earl Grey, hot, by default?
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John B. Cole @lsmsa1990.bsky.social · 01/10/2026
So much this. I find it very difficult to get my phone to play the correct podcast by talking to it, much less anything important.
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Comfortably Numb @numb.comfortab.ly · 29/09/2026
SO YOU ARE A CATHOLIC? NAME FIVE CATS!
Black cat face close up
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John B. Cole @lsmsa1990.bsky.social · 29/09/2026
I made gumbo today. After rendering the fat out of 8 chicken thighs for sauteeing my trinity, I was left with 8 perfectly crispy skins. As the chef, it was my prerogative to eat [REDACTED] of them. I regret nothing.
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John B. Cole @lsmsa1990.bsky.social · 28/09/2026
If they stop making Salted Nut Rolls I'm likely to be driven to intemperate behavior.
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John B. Cole @lsmsa1990.bsky.social · 28/09/2026
This is a bad bill that will benefit the NCAA and the conferences, but won't fix the transfer portal, which is the real problem. As an LSU alumnus, I wish the schools would do something about the rape and all, too, but I guess Athletic Directors don't get paid for protecting people from athletes.
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Andrew D Wilson @adw.bsky.social · 28/09/2026
“Huh. That’s weird.” is the essence of being a scientist. When did that become a surprise to people?
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John B. Cole @lsmsa1990.bsky.social · 28/09/2026
Dr. Benjamin V. Lehmann at MIT has recently made a breakthrough in this area: arxiv.org/html/2504.00....
arxiv.org
Higher multipoles of the cow
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John B. Cole @lsmsa1990.bsky.social · 27/09/2026
"Choosin' Texas" is a perfectly cromulent song and the dance is fun. There doesn't need to be a Discourse about it. I have a bad memory and often get the title wrong (it's not "Leavin' Texas"?) and I have no idea what the singer's name is. She sounds just a hair Lucinda, sometimes, which I like.
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GONZO the Ca'at @gonzo.bsky.social · 27/09/2026
Git outto heer yu dumb pinnople!
Orange and white cat yelling at a pineapple
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Jerry Chen @jcsalterego.bsky.social · 26/09/2026
when you get a good DM
a screenshot of the message: "This isn’t FOIA-able, right?"
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
I refuse to address the New York Times list of best TV shows of the 21st century on the grounds that they're going to be haunted by Bourdain, anyway, and I can't write anything worse than that.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
There are no penalties too harsh for these folks. I hope their luggage ends up in Cleveland and they're in Miami. I hope their favorite snack runs out just before the cart reaches them, I hope the person in the seat in front of them reclines, all the way back. Foul spirits.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
Yeah, no, absolute slop. I couldn't properly write 14 book chapters in a year.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
@baldwin.senate.gov I can't believe y'all have nothing better to spend floor time on than Ted Cruz's "Protect the NCAA's Monopoly" bill.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
All you have to do is just ask if you can get a PDF off their paper. I've never asked anyone why they wanted it. :-)
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
I put copies of all my papers on my personal website.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
Because some of us are old and maybe don't keep up with nomenclature changes like we used to?
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
confusing mess that place is. Is there actually a system? That is communicated to customers? And followed by the staff (who, to be clear, were working their butts off)? Because I'm not sure what the point of calling ahead is if it takes as long - or longer - than just using the kiosk.
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John B. Cole @lsmsa1990.bsky.social · 25/09/2026
We're Costco members but aren't really Costco People. I kind of hate going there because the other customers are awful and the cashiers get mad if you don't want to BOGO the cream cheese Danishes. I rolled by this evening to get a couple of pizzas, and I pity every worker in the food court, what a.
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Tamar Haspel @tamarhaspel.bsky.social · 24/09/2026
Maybe if you refuse to answer direct questions, Congress shouldn't confirm you. Just a thought.
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
So that's the deal with birds.
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
If I was a grown person who didn't know his own address, I probably wouldn't admit it. What are we even doing here? That's not admirable, or evidence of mental dexterity, or systems thinking, or whatever. In fact, I don't even believe him.
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
I have questions about some NIFA panels...
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
There are so many gaps in my knowledge of music, but why was "Bitches Brew" so controversial in the jazz world? Hadn't Ornette Coleman already burned everything down with "Free Jazz"?
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
forwardtheater.com/show/steady-...
forwardtheater.com
Steady She Goes
Riding on a current of classic sea shanties, this world premiere adventure traces the real-life story of Mary Ann Brown Patten and her sailing voyage around Cape Horn after her husband, the captain, f...
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
I am so grateful to this post because I'd not yet heard that. It's fantastic. God bless our aviation-shanty overlords. Also, go see the sea shanty-based retelling of Mary Ann Brown Patten's story, "Steady She Goes", by Erica Berman, it's fantastic.
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
@bsky.app, what the heck? Why am I getting "Invalid handle" messages on my profile, and "Failed to verify handle. Please try again." when I try and re-validate my domain? The file's there. The contents are correct. This had been working for, I don't know, a year or more?
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
The Covid booster I got yesterday is kicking my butt much more than the flu or pneumonia shots did, but hopefully I'll avoid the post-Expo wave of sickness that happens every year now.
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John B. Cole @lsmsa1990.bsky.social · 24/09/2026
You could be right that assume of good bumbling is intentional, but I sincerely believe he's not very bright and isn't very good at his job.
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
I suggest it's incompetence because a skilled speaker should be able to deliver both "victories" on which their members could campaign and allow the executive branch to operate with few limits. Mike is not good at his job.
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
Imagine the poor staffer who had to explain furries to the dumbest member of Congress. Or don't, they work for him voluntarily.
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
I sure hope Mike Johnson's startling incompetence pays dividends in November. House leadership has utterly failed its members.
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
I was skeptical, but any kind of frozen potato-like product is 100x better from the air fryer than the oven. 🤷‍♂️
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
The only thing building me back is I'd lose the ability to easily share sides with my colleagues, and we do a lot of that.
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John B. Cole @lsmsa1990.bsky.social · 23/09/2026
I'm generally calmer as I age, but the absolute trash that is the "styling" system in Microsoft PowerPoint does terrible things to my blood pressure. "Slide Master" my foot. I'm about 30 seconds away from becoming a Beamer person, I swear, then at least formatting would work properly.
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John B. Cole @lsmsa1990.bsky.social · 22/09/2026
Utter trash. California deserves better. As if we're not already years into learning (yet again) why imperial presidents/governors/potentates are Bad, Actually.
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John B. Cole @lsmsa1990.bsky.social · 22/09/2026
I'm reading @scotthawkinswrites.bsky.social new novel, "Blacktail", and it's so good. Like "The Library at Mt. Char" it's not always an easy read, but I can barely put it down.
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John B. Cole @lsmsa1990.bsky.social · 21/09/2026
Republicans have destroyed this country. Since when do grapes cost as much per pound as ground beef? The grocery store has lost its mind.
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John B. Cole @lsmsa1990.bsky.social · 21/09/2026
To paraphrase Val Kilmer's character in "Real Genius", is that a design problem or an engineering problem? ;-) Maybe we need to actually validate all of the candidate QTL before we put them in models where they fail to increase prediction accuracy.
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John B. Cole @lsmsa1990.bsky.social · 21/09/2026
Just plot the proportion of variance explained, draw a horizontal line in a convenient spot, and talk about all the cool signals, no P-value needed because it's Empirical Bayes [sic].
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John B. Cole @lsmsa1990.bsky.social · 21/09/2026
"Suggestive" P-values in GWAS aren't a thing. I, too, know the frustration of seeing a SNP associated with an interesting gene fall short of genomewide significance. But, troublesome as P-values are, if we're using them as a decision rule then they have to mean something.
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John B. Cole @lsmsa1990.bsky.social · 21/09/2026
That sounds incredibly depressing.
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