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Lizzie Dellar

@lizziedellar.bsky.social
338 followers 275 following 10 posts

Postdoc @mndoxford.bsky.social @ndcnoxford.bsky.social working on protein biomarkers of ALS/MND and extracellular vesicles.

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Reposted by Lizzie Dellar
Steph Fowler @stephfowler.bsky.social · 07/07/2026
We're hiring for an exciting new Oxford x Rosalind Franklin Institute collaboration. The role will support cryo-EM workflows to investigate subcellular changes associated with dementia. ➡️https://bit.ly/4ePc83z #StructuralBiology #CryoEM #Neurodegeneration #Neuroscience #ResearchJobs
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Reposted by Lizzie Dellar
Dementia Researcher @dementiaresearcher.bsky.social · 21/06/2026
Watch the main plenary & flash talks from the @arukthamesv.bsky.social Dementia Research Day. The playlist features research on Alzheimer’s, Lewy body dementias, ALS, tau biology, proteomics, biomarkers, neuroinflammation & CST. www.dementiaresearcher.nihr.ac.uk/research-fro...
dementiaresearcher.nihr.ac.uk
Research from the ARUK Thames Valley Conference - DEMENTIA RESEARCHER
Watch the main plenary and five flash talks from the ARUK Thames Valley Research Conference, covering dementia science from cells to care.
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 28/04/2026
Next, a methods paper led by @lizziedellar.bsky.social, demonstrating the utility of tetraspanin immunocapture for enriching extracellular vesicles #EVs from small volumes of cerebrospinal fluid for biomarker discovery. link.springer.com/article/10.1...
link.springer.com
Tetraspanin-based immunocapture for high-depth proteomic profiling of extracellular vesicles from cerebrospinal fluid for biomarker discovery - Clinical Proteomics
Background Due to its proximity to cells of the central nervous system, cerebrospinal fluid (CSF) is an important source of novel biomarkers for neurological diseases. Membrane-bound extracellular ves...
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 18/06/2025
Great talk by Beatrix from the group on targeted long-read sequencing of the C9orf72 HRE at the ARUK Thames Valley Network Research Day in Oxford today #ALS #FTD
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Reposted by Lizzie Dellar
Molecular Neurodegeneration @molneurodegen.bsky.social · 10/06/2025
#ExtracellularVesicles in #TDP43 proteinopathies: pathogenesis and #biomarker potential Elizabeth R. Dellar @lizziedellar.bsky.social Lara Nikel, Stephanie Fowler...Alexander G. Thompson #exosome #ALS #FTD molecularneurodegeneration.biomedcentral.com/articles/10....
molecularneurodegeneration.biomedcentral.com
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...
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Lizzie Dellar @lizziedellar.bsky.social · 10/06/2025
Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE. doi.org/10.1186/s130...
doi.org
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...
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Lizzie Dellar @lizziedellar.bsky.social · 23/04/2025
En route for #ISEV2025! If you want to chat EV enrichment from #brain #blood and #CSF for biomarker discovery in neurodegenerative diseases, then come and find me later this week 🫧
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Reposted by Lizzie Dellar
Dementia Researcher @dementiaresearcher.bsky.social · 11/04/2025
“The time to write a fellowship is when it feels right for you.” Great advice from @dryvonnecouch.bsky.social’s new guest blog on writing your first fellowship. www.dementiaresearcher.nihr.ac.uk/blog-writing...
dementiaresearcher.nihr.ac.uk
Dr Yvonne Couch - Blog – Writing Your First Fellowship
Dr Yvonne Couch shares wisdom (and warnings) on writing your first fellowship application — from timing and ideas to funding and salary tips.
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 27/03/2025
Also contributing were Beatrix with her poster on long-read sequencing of #C9orf72 HRE and @lizziedellar.bsky.social with her poster on #ExtracellularVesicle -based biomarker discovery in CSF.
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 27/03/2025
The @mndoxford.bsky.social team enjoyed the day at the Oxford #MDUK Neuromuscular Centre meeting yesterday. In the #ALS/#MND session Alex spoke on our studies of at-risk pre-symptomatic populations, and Kevin on the path from pre-clinical models to experimental medicine.
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 21/03/2025
Excellent talk by Lizzie @lizziedellar.bsky.social from the group on discovery and validation of early biomarkers in #ALS at the Oxford Neuroscience Symposium this week.
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Lizzie Dellar @lizziedellar.bsky.social · 24/01/2025
Come and work with me! Research position open to work on isolation of #extracellular #vesicles for biomarker discovery in #ALS #MND. See link for more details, and reach out if you have questions. my.corehr.com/pls/uoxrecru...
my.corehr.com
Job Details
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 15/01/2025
Come and join us! Research assistant position open at @mndoxford.bsky.social @ndcnoxford.bsky.social, working on collecting neuroimaging data in #ALS and #FTD. Previous research experience with humans is essential. This post would suit a #Psychology or #Neuroscience graduate. See link below for info
my.corehr.com
Job Details
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Reposted by Lizzie Dellar
Oxford MND Research @mndoxford.bsky.social · 06/12/2024
We also have several group members giving platform talks as well as a plenary lecture! We would be delighted to see you there - see below for our presenters and talks #MND #ALS @mndassoc.bsky.social #alsmndsymp
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Oxford MND Research @mndoxford.bsky.social · 06/12/2024
We are excited to be here in Montreal for @mndassoc.bsky.social #alsmndsymp! We would be delighted to see you at our posters - see below for our presenters and poster numbers #MND #ALS
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Reposted by Lizzie Dellar
Björn Vahsen @bvahsen.bsky.social · 22/11/2024
@mndoxford.bsky.social is now also here on Bluesky. Give it a follow to hear research updates from the whole Oxford MND Centre!
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Lizzie Dellar @lizziedellar.bsky.social · 21/11/2024
Congrats to Steph Fowler and team for their excellent work showing the presence of tau filaments in #extracellularvesicles derived from brain tissue in Alzheimer's disease, out in @NatureNeuro today. www.nature.com/articles/s41... Excited to see more on this!
nature.com
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease - Nature Neuroscience
Using cryo-electron tomography (cryo-ET) and proteomics, this study identifies the tethering of pathological tau filaments within defined brain extracellular vesicles in Alzheimer’s disease, shining l...
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Reposted by Lizzie Dellar
Dr Yvonne Couch @dryvonnecouch.bsky.social · 11/11/2024
Here's number 2: (hopefully by now you have figured out where to find them and can head over and browse at your leisure!) www.dementiaresearcher.nihr.ac.uk/guest-blog-i...
dementiaresearcher.nihr.ac.uk
Dr Yvonne Couch - Is Leadership Important In Science?
Dr Yvonne Couch talks about leadership in research, exploring different styles and approaches and how you might apply them.
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Coleman Lab @colemanlab.bsky.social · 18/11/2024
This week’s Science Without Anguish post is out: the slippery slope to imposter syndrome in research and how to escape it. Please tell your colleagues on or off social media. 🧪 www.sciencewithoutanguish.com/blog/we-are-...
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Tom Driedonks @tomdriedonks.bsky.social · 19/11/2024
EV people unite! 😁
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Reposted by Lizzie Dellar
PRIDE Database @pride-ebi.bsky.social · 19/11/2024
PXD051859 🚨 Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 levels in asymptomatic C9orf72 hexanucleotide repeat expansion carriers. 🚨 New dataset alert! 🚨
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Lizzie Dellar @lizziedellar.bsky.social · 18/11/2024
(1/3) Happy to share our new work assessing protein changes in CSF of 48 asymptomatic C9orf72 variant carriers at higher risk of #ALS and #FTD. We find an elevation in levels of UCHL1 protein, even in the absence of elevation in #neurofilament (NFL). onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl‐Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers
Objective To identify biochemical changes in individuals at higher risk of developing amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD) via C9orf72 hexanucleotide repeat expansion...
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