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Lindsay Hohsfield, Ph.D.

@lindsayhohsfield.bsky.social

Neuroscientist. Alzheimer’s researcher. CNS myeloid cell enthusiast in Kim Green’s lab @UCI. Founder of Youngtimers. Advocate for rare early onset Alzheimer’s. Toddler and husky mom.

Posts Replies Media

Lindsay Hohsfield, Ph.D. @lindsayhohsfield.bsky.social · 03/06/2025

Excited to share our new paper out in @cp-neuron.bsky.social today! We discovered the neuroanatomical route that myeloid cells use to enter the brain parenchyma. Check it out here: authors.elsevier.com/c/1lCYs3BtfH...

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Reposted by Lindsay Hohsfield, Ph.D.

John Lukens @lukensjohnr.bsky.social · 03/06/2025

Identification of the velum interpositum as a meningeal-CNS route for myeloid cell trafficking into the brain: @cp-neuron.bsky.social www.cell.com/neuron/fullt...

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Reposted by Lindsay Hohsfield, Ph.D.

Science Magazine @science.org · 03/06/2025

"… we are in a propitious position to accurately and precisely determine who is at high risk of developing #AlzheimersDisease years before signs of even mild cognitive deficit," writes @erictopol.bsky.social‬ in a new #ScienceExpertVoices article. Read more: scim.ag/4koj8F5

"… there has never been a greater opportunity to identify individuals at high risk for Alzheimer’s and prevent them from developing the disease …" Eric Topol, Scripps Translational Science Institute

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Lindsay Hohsfield, Ph.D. @lindsayhohsfield.bsky.social · 04/12/2024

Hi Bluesky! I’m Lindsay Hohsfield and I work as an Associate Researcher at the University of California, Irvine in Kim Green’s lab. I study #microglia and #Alzheimer’s disease. I also founded Youngtimers, a nonprofit for rare young onset Alzheimer’s disease.

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Reposted by Lindsay Hohsfield, Ph.D.

John Lukens @lukensjohnr.bsky.social · 26/11/2024

Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients www.nature.com/articles/s41...

nature.com

Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients - Nature Communications

In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ther...

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