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Lee Bardwell

@leebardwell.bsky.social

Scientist, educator, father, concerned citizen. Professor at UC Irvine Dunlop School of Biological Sciences.

Lee Bardwell @leebardwell.bsky.social · 08/01/2026

A preprint of our latest manuscript is out on bioRxiv. We used AlphaFold3 to predict the structure of the human GLI1-SUFU, GLI2-SUFU and GLI3-SUFU complexes (and fly Ci-Sufu), revealing three novel interfaces. www.biorxiv.org/content/10.6...

Structure of human GLI2-SUFU complex, Figure 1D from Bardwell et al. preprint

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Reposted by Lee Bardwell

Gwênlyn Glusman (she/her) ☸️ @gwenlyn.bsky.social · 12/07/2025

"Announcing the Biomedical Data Translator: Initial Public Release" pubmed.ncbi.nlm.nih.gov/40635371/ Translator is the knowledge-graph integration system we're developing to support hypothesis generation by scientists. Funded by NCATS. As I said in the past, best consortium ever. Awesome people. 🧪

pubmed.ncbi.nlm.nih.gov

Announcing the Biomedical Data Translator: Initial Public Release - PubMed

The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the ...

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Reposted by Lee Bardwell

Grace Bower @gracebower.bsky.social · 22/11/2024

It was exciting to dig into all the new discoveries in long range gene regulation while writing this!

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Reposted by Lee Bardwell

Katherine Xue @ksxue.bsky.social · 19/11/2024

Hi friends new and old! I study how microbes interact and evolve in complex communities like the human gut microbiome.🦠🧬💩 I'm thrilled to share that I'm starting a lab at UC Irvine in April 2025 and am recruiting at all levels - please spread the word! kxuelab.com More about my work below...🧵1/n

kxuelab.com

Xue lab at UC Irvine

Ecology and evolution in the human gut microbiome

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Lee Bardwell @leebardwell.bsky.social · 19/11/2024

Cell division in the developing embryo needs to be fast, but not sloppy. An illuminating paper on this topic, from the labs of Pablo Lara-Gonzalez and Arshad Desai (which my lab was privileged to help with) is in this issue of JCB. Also a spotlight article on our work by Boland and Kamenz!

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Lee Bardwell @leebardwell.bsky.social · 18/11/2024

This is some of what we do in my lab at UC Irvine faculty.sites.uci.edu/bardwell

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