Reposted by Luca CiandriniCees Dekker @ceesdekker.bsky.social · 22/07/2026We built a a self-dividing synthetic cell ! Check out this #CDlab preprint on BioRxiv: www.biorxiv.org/content/10.6... Great work by 1st author Charu Sharma who encoded dynaminA in a genome and expressed that in liposomes that then divide into daughter cells! Collaboration with Koenderink lab! 24726
Reposted by Luca CiandriniAaron Sojourner @aaronsojourner.org · 25/07/2026Admirable clarity @science.org 4974912713
Reposted by Luca CiandriniStatistical Physics of Cells and Genomes @spcggroup.bsky.social · 30/06/2026New SPCG review paper on "component systems" from genomes and ecosystems to language, cities, and software. How do we separate universal combinatorial patterns from system-specific signatures? journals.plos.org/complexsyste... 032
Luca Ciandrini @lciandrini.bsky.social · 03/06/2026New paper out today in PRX Life! We developed a stochastic transport model showing how antibiotic-induced ribosome pausing may trigger collective jamming on mRNA, with longer transcripts paying a disproportionate price. Read it here! 👇 🔗 doi.org/10.1103/vrqp... 183
Reposted by Luca CiandriniMaerkl Lab @maerkl-lab.bsky.social · 26/05/2026Saeed's paper is now published: "PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized proteins" www.nature.com/articles/s41...nature.comPURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized proteins - Nature CommunicationsBuilding a self-replicating biochemical system remains a challenge in synthetic biology. Here the authors demonstrate that the cell-free protein synthesis PURE system can be reconstituted from protein... 054
Reposted by Luca CiandriniCarl T. Bergstrom @carlbergstrom.com · 22/05/2026“Units of the NIH are privately directing grantees to request permission in advance for any co-authorship with a scholar affiliated with a foreign institution, even if all the work was done in the United States.” Grantees also told to remove papers with foreign authors from progress reports.science.orgU.S. researchers face new restrictions on publishing with foreign collaboratorsNIH, NASA grantees are confused and concerned amid agencies’ piecemeal communication 31417259
Reposted by Luca CiandriniStatistical Physics of Cells and Genomes @spcggroup.bsky.social · 14/05/2026New SPCG paper. With the Bokinsky lab (Milan Lacassin), Andrea Ripamonti modeled the competition for transcriptional resources. Our data and model jointly show how E. coli’s second messengers ppGpp & cAMP reshape gene expression globally. www.sciencedirect.com/science/arti...sciencedirect.comTranscriptional competition biases the effects of second messengers in Escherichia coliCells regulate gene expression by balancing transcriptional resources across different functional groups of genes. In Escherichia coli, second messeng… 052
Reposted by Luca CiandriniBiophysical Paris @parisseminar.bsky.social · 27/04/2026jmc2026.sciencesconf.org physics of bacteria and other microorganisms, which will take place at the next Condensed Matter Days in Toulouse, 26-30 october 2026.jmc2026.sciencesconf.orgJournées de la Matière Condensée 2026 - Sciencesconf.org 021
Reposted by Luca CiandriniJordy F. Botello @jbotello.bsky.social · 10/03/2026Some molecular machines, like ribosomes, can persist for long periods of time in cells. Could molecular aging of ribosomes shape how proteins are made? In our new preprint we track ribosomes as they age in cells and uncover unexpected effects on translation (1/10) www.biorxiv.org/content/10.6... 412851
Reposted by Luca CiandriniYoung Biophysicists Meeting @youngbiophymeet.bsky.social · 05/02/2026Submission open for the ninth YBM Meeting (deadline - 19th February)! Abstract submission link: forms.gle/SBeQeAp9MR2U... 044