iiinova — where your digital self keeps evolving

Reposted by Lars Henning

Health Nerd @gidmk.bsky.social · 24/06/2026

Specifically, we found that 1% of all Cochrane reviews cite a paper from authors with >24 entries for correction or retraction in the @retractionwatch.com database. People like Boldt, Fujii, Asemi, etc. This is not great.

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Lars Henning @larshenningmd.bsky.social · 10/07/2026

Fortsatt sommarläsning med lån från bibblan "Vad vi talar om när vi talar om klimakteriet" med humaniora-perspektiv. En första kvalitets-check visar högsta betyg med citering av HTA-enheten Camtös testosteronrapport och flertal referenser från idéhistoriker Karin Johannisson

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Lars Henning @larshenningmd.bsky.social · 29/06/2026

Rekommenderad sommarläsning i nyaste utgåva av Filter "Kan det vara ... förklimakteriet?" från Madelene Pollnow med massor lästips för den intresserade. Jag har precis reserverat i mitt bibliotek "Vad vi talar om när vi talar om klimakteriet"

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Reposted by Lars Henning

George Davey Smith @mendelrandom.bsky.social · 18/06/2026

How strong is the evidence that live shingles vaccination prevents the risk of dementia? A talk yesterday @oxprimarycare.bsky.social on this available here youtu.be/qlTnnQytOJ0

youtu.be

Guest Lecture 17 June 2026, does the shingles vaccine prevent dementia?

YouTube video by Nuffield Department of Primary Care Health Science

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Lars Henning @larshenningmd.bsky.social · 17/05/2026

Stor läsrekommendation"Vård utan värde - undvik lågvärdevård och blir en klokare kliniker". Två av bokens redaktörer med David Gyll och Johan Bengtsson har föreläst på en av HTA-enheten Camtös temadagar och Camtö's verksamhetschef Louise Olsson som bidragit med ett kapitel om lågvärdeforskning.

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Lars Henning @larshenningmd.bsky.social · 17/05/2026

Richard Lehman put patient values and interests always in the centre of health-care. Richard was keen about debate and critical discourse. I recommend to take a look on Richards weekly column in BMJ about important clinical trials which he wrote for 12 years. blogs.bmj.com/bmj/2018/08/...

blogs.bmj.com

Richard Lehman's sunshine act - The BMJ

Alison Tonks speaks to Richard Lehman about writing research reviews and what he’ll be doing next For 20 years, GP Richard Lehman reviewed the headline research papers in general medical [...]More...

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Lars Henning @larshenningmd.bsky.social · 24/04/2026

Funny. Here in Sweden Oracles IT-platform Millenium has been a graveyard for tax money in the billions of Swedish Kronor in two big regions.

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Lars Henning @larshenningmd.bsky.social · 18/04/2026

Efter den intellektuella kollapsen inför öppen kamera i Aktuellt igår om Finger-modellen och demens blev det helt klart att Socialstyrelsen behöver se över sitt arbetssätt om svenska befolkningen skall känna tillit i fortsättningen till denna viktiga expert myndighet www.svtplay.se/video/eEqqDL...

svtplay.se

Aktuellt – Igår 21:00

Demensvård: Hur viktig är sund livsstil? • Kriget i Ukraina: Kungen hos Zelenskyj • Schack: Konsten att tänka positivt

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Reposted by Lars Henning

Mike Johansen @mikejohansenmd.medsky.social · 22/03/2026

Shingrix rct enrolling 162k looks to be starting this month will look at MACE and dementia dx. This makes me happy to know we'll get an answer to the 9 million obs studies.

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Reposted by Lars Henning

Peter Tennant @pwgtennant.bsky.social · 25/02/2026

So, what have we learnt from this paper: First, that this "AI stethoscope" offers no apparent benefit in practice. Second, that you still can't trust a per-protocol analysis presented in a general medical journal. Third, as with anything AI, you have to look beyond the hyped headline. 🧵 16/

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Lars Henning @larshenningmd.bsky.social · 18/12/2025

On the positive side this 👇 stresses the importance as part of critical reading to check references in scientifical publications. Much too often they didnt make any sense already in the pre-AI-era

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Lars Henning @larshenningmd.bsky.social · 12/12/2025

To achieve the same benefit with less intervention is one of the big beauties in medicine. This one 👇 has huge implications for global health.

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Lars Henning @larshenningmd.bsky.social · 12/12/2025

Den här historien bekräftar ett tidlöst citat från f.d. tyske förbundskanslern Helmut Schmidt "Den som drabbas av visioner bör gå till en läkare" lakartidningen.se/nyheter/visi...

lakartidningen.se

Vision e-hälsa – drömmen om digitalisering som sprack

2025 skulle Sverige vara bäst i världen på digitalisering inom sjukvården. Så blev det tyst. Vad hände?

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Lars Henning @larshenningmd.bsky.social · 11/12/2025

Mycket positivt att TLV tydlig markera emot olämplig förskrivning av licensläkemedel. www.tlv.se/download/18.... För kapitlet om svinsköldkörtelextrakt (s 44-45) måste rimligen CAMTÖ's systematiska översikt varit en inspiration där jag fick bidra till.

tlv.se

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Lars Henning @larshenningmd.bsky.social · 05/12/2025

"Surrendering to demands for higher drugprices (25% if I understood correctly) means that the NHS and patients will bear the cost, without any guarantee of greater innovation or improved health outcomes"

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Lars Henning @larshenningmd.bsky.social · 01/12/2025

Its 1st of december and fortunately time again to delve into Anna's new learnfull advent calendar on research Integrity.

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Reposted by Lars Henning

František Bartoš @fbartos.bsky.social · 01/12/2025

We just preprinted a huge meta-meta-analysis examining the effects of exercise on cognition, memory, and executive function In short - 2239 effect sizes - extreme between-study heterogeneity - extensive publication bias - some subgroup/exercise-specific effects More below (doi.org/10.31234/osf...)

doi.org

OSF

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Lars Henning @larshenningmd.bsky.social · 29/11/2025

A lilliputian step for mankind, a giant step for the Green Party in Germany accepting the obvious that treatments with at best placebo-effect in clinical trials like homeopathy should not get reimbursed.

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Lars Henning @larshenningmd.bsky.social · 29/11/2025

Viktig artikel i @svenskadagbladet1.bsky.social om Trumpism med betydelse om prissättning av läkemedel i Europa Trump: Européer ska betala mer för medicin www.svd.se/a/JOWXqR/tru...

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Lars Henning @larshenningmd.bsky.social · 26/11/2025

New expression of concerrn in @bmj.com possibly causing waves of concern among Swedish scientists who earn their careers by harvesting the formidable Swedish registries. When its not ok anymore to assume causal effects in observational trials where will be the fun left? www.bmj.com/content/391/...

bmj.com

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Lars Henning @larshenningmd.bsky.social · 26/11/2025

In my opinion the authors of any systematical review should not have such a tragicomical lengthy conflict of interest section like in this case

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Lars Henning @larshenningmd.bsky.social · 24/11/2025

"A massive Swedish study examined hormonal birth control risks. But the nuances of such studies get lost on social media." Comment: nuances were lost also in traditional media-outlets and the initial press-release by Uppsala University

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Lars Henning @larshenningmd.bsky.social · 24/11/2025

Superintresting and learnfull blogg on HPV-vaccination which illustrated clearly how challenging triangulation for longterm clinical effects with meaningful surrogate endpoints are. My greatest respect for not using the Danish ø a single time

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Reposted by Lars Henning

Hilda Bastian @hildabast.bsky.social · 24/11/2025

We've had to wait a long time to get to this point! With this new pair of Cochrane systematic reviews, the weight of the evidence has tipped very heavily in favor of HPV vaccination. My new post @plos.org absolutelymaybe.plos.org/2025/11/24/t... #Vaccines

absolutelymaybe.plos.org

This Evidence Fundamentally Shifts the Debate About the HPV Vaccine - Absolutely Maybe

We’ve had to wait a long time to get to this point. If cervical cancer develops after HPV infection, it will take…

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Lars Henning @larshenningmd.bsky.social · 21/11/2025

This is the kind of paper which is unethical to have behind paywall as it is directed to cancerpatients and their families. Reading might decrease unnecessary anxiety and stress and might improve quality of life and intimacy with loved ones while on chemotherapy. Recommended read.

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Lars Henning @larshenningmd.bsky.social · 21/11/2025

www.dagensmedicin.se/alla-nyheter... En av våra cancerpatienter får idag utan krångel en blodtransfusion i hemtrakten i Fagersta. Jag blev nästan gråtfärdig. Många take home messages här i artikeln: - fördel med små enheter och eget ansvar -Alltid bra att utgå från patientens behov & få jobb gjort

dagensmedicin.se

”Vi pratar inte pengar” – modellen som gjort Fagersta till ett föredöme i nära vård

När andra fastnar i ekonomi gjorde Fagersta tvärtom: de slutade prata pengar och började samarbeta. Resultatet är ett närvårdsteam som på bara tre år gjort nära vård till vardag – och förändrat patien...

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Reposted by Lars Henning

Grodaeu @groda.eu · 20/11/2025

This is a problem for scientific communication. A total lack of causation can never be proven for anything. You cannot prove that playing cello in your underwear doesn't cause autism. These charlatans exploit that.

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Lars Henning @larshenningmd.bsky.social · 20/11/2025

To fail in critical assessment of the published scientifical litterature (which implies to identify the shitty garbage part of published research) costs life

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Lars Henning @larshenningmd.bsky.social · 18/11/2025

Its bad that this important patient-centered article is not open-access. The only advice i give to my patients on chemotherapy (not backed by evidence) is that they might avoid to kiss a person with fever. And that they should try to gather some cool moments of gold while on this toxic treatment.

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Reposted by Lars Henning

ERROR @error.reviews · 14/11/2025

Are methodological and causal inference errors creating a false impression that the gut microbiome causes autism? In this strong analysis, Mitchell, Dahly, and Bishop question the evidence. They show that triangulation in science requires multiple robust lines of research.

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Lars Henning @larshenningmd.bsky.social · 06/11/2025

9th of december free 2-hour introduction online workshop on the INSPECT-SR tool for assessing trustworthiness of randomised controlled trials (RCTs. 👇

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Lars Henning @larshenningmd.bsky.social · 03/11/2025

Detection for fabricated or unlikely data in RCT's should be mandatory for HTA-units as well 👇

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Reposted by Lars Henning

Integral Answers @integralanswers.bsky.social · 02/11/2025

10/ Protecting every child protects the world. 🌍 That’s what vaccine equity means — a safer, fairer future for all. Learn more: 🔹 The Lancet: tinyurl.com/3vbkwrfx 🔹 Nature: tinyurl.com/yc3v84uj 🔹 Gavi: gavi.org #GlobalHealth

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Lars Henning @larshenningmd.bsky.social · 02/11/2025

Good study which contributes to informed decision making of women when choosing contraceptives. But also an example of failed communication of research findings in the 🇸🇪 media. A school-book example imo where it should be forbidden to use relative risks and mandatory with absolute risk.

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Reposted by Lars Henning

The Cochrane Collaboration @cochrane.org · 31/10/2025

Evidence synthesis for decision making: navigating the chaos of the real world | Online 🗓️ 6 November This webinar will discuss some of the challenges in evidence synthesis when the available evidence may not answer all the questions. 🔗 Register here: universityofgalway-ie.zoom.us/webinar/regi...

universityofgalway-ie.zoom.us

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Lars Henning @larshenningmd.bsky.social · 31/10/2025

Good example of nice description of disadvantages with multidisciplinary conferences in cancer-care and bad solutions (AI as the rescue). My 2 cents: centralization has gone too far. Invest in oncologists close to patients and listen to them and you'll do better decisions www.bmj.com/content/391/...

bmj.com

Cancer decision making needs a radical rethink

Long meetings involving dozens of clinicians can delay patient care and leave no room for service improvement. It’s time for a fresh approach, say Tom Roques and colleagues For 30 years, multidiscip...

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Lars Henning @larshenningmd.bsky.social · 31/10/2025

Debatt-artikel efter HTA-enhet Camtös rapport om exploderande CT-användning. Camtö uppmärksammade i rapporten att det saknas organiserad statistik om användning av CT där man var tvungen att använda framtagen data från ett företag ”Ökningen av CT behöver stoppas” www.svd.se/a/5EAgP6/ove...

svd.se

”Ökningen av CT behöver stoppas”

DEBATT. Överläkare: Sjukvården är fast i en farlig spiral där krav på perfektion, produktion och emellanåt omöjliga förutsättningar betalas med ett ökande antal CT-undersökningar.

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Reposted by Lars Henning

Julia M. Rohrer @dingdingpeng.the100.ci · 28/10/2025

This is an excellent point that generalizes. Researchers often defend suboptimal practices by referring to future studies with better designs. But: Why would anybody run those studies when you can just throw a bunch of variables into a regression and make sweeping "preliminary" claims?

Defences of factors associated with studies
Results are exploratory or hypothesis generating
Researchers might accept that limitations exist in
a “factors associated with” analysis, but argue that
the results give a useful initial indication of potential
risk factors. Researchers might say that the results
are hypothesis generating and can inform confirmatory
studies with a more focused study design. But
how often has an important hypothesis been generated
for the first time from a “factors associated with”
study, and then confirmed to be true? We have yet to
identify an example. If readers can identify examples,
which we would like to hear about, we wonder
if these justify the waste from the large number of
“factors associated with studies that are done each
year.

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Lars Henning @larshenningmd.bsky.social · 26/10/2025

Sociologen @rolandpaulsen.bsky.social med mycket intressant berättelse om testosteron-industrins bakgrund och idéhistorie inklusive hänvisning till HTA-enheten CAMTÖ's debattartikel och ny boktips om överdiagnos www.dn.se/kultur/rolan...

dn.se

Roland Paulsen: Jag mätte mina testosteronhalter – resultatet var chockerande

Alla från Trump till Andrew Tate skryter med sina höga testosteronhalter. En dag började Roland Paulsen undra om han själv kanske behövde tillskott.

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Lars Henning @larshenningmd.bsky.social · 22/10/2025

Dyra sprutan kan skydda mot demens www.svd.se/a/OowPbb/bal... Fascinerande artikel som ställer frågan om inte en välgjord observationsstudie som innefattar ett naturligt experiment skall vara tillräckligt för att introducera bältrosvaccination för äldre i svenska vaccinationsprogrammet.

svd.se

Dyra sprutan kan skydda mot demens

Vaccin mot bältros tycks minska risken för demens, enligt flera studier. Därför bör de dyra sprutorna nu införas i det svenska vaccinationsprogrammet, anser forskare.

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Lars Henning @larshenningmd.bsky.social · 22/10/2025

Unfortunately sold out for now. But hopefully more free online workshops in the future

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Lars Henning @larshenningmd.bsky.social · 21/10/2025

Still painful not to be able to read Cochrane Reviews during the first year in full. Much more painful that I wasted resources for far too many years with my misguided non-evidence routine to give blood transfusion to my cancer patients with Hb<100. #choosewisely

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Lars Henning @larshenningmd.bsky.social · 19/10/2025

Open access for papers with general interest for patients and their families is as well a necessity. In this screenshot from X by Bishal Gyawali you get at least the first page of an important read if you are interested or in need of cancer research

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Reposted by Lars Henning

hannaradonc.bsky.social @hannaradonc.bsky.social · 18/10/2025

Patient-, care partner-, and clinician-proposed solutions to address the time toxicity of cancer care link.springer.com/article/10.1...

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Lars Henning @larshenningmd.bsky.social · 16/10/2025

Kommentarer lyfter debattartikeln utanför lilla gyn-onkologin. Min favorit-kommentar från Jörn Schneede Läkemedelscentrum Västerbotten. Tror ni att den här debatten kommer påverka hur svenska nationella vårdprogram tas fram?

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