Big dogs age faster than little ones
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…ageing in dogs is accompanied by changes in certain chemical groups added onto DNA that can control gene activity. In big dogs, these epigenetic changes accumulate at a faster rate…
www.science.org/doi/10.1126/...
science.org
Epigenetic aging and transposon dysregulation reflect size-related lifespan compression in dogs
The extraordinary lifespan variation in domestic dogs provides a natural experiment for testing how intrinsic rates of biological aging shape lifespan. Using 1640 methylomes from 894 dogs, we develope...