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kmcdonnell.bsky.social

@kmcdonnell.bsky.social

Reposted by @kmcdonnell.bsky.social

Nikolai Slavov @slavov-n.bsky.social · 01/09/2026

Accurately quantifying over 700K precursors in a single 9-plexDIA set of 20ng proteomes is a new milestone. JMod achieves high quantitative accuracy over a 32-fold dynamic range of proteome spiked-in ratios across single-cell and bulk sample sizes. 1/ doi.org/10.1101/2025...

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kmcdonnell.bsky.social @kmcdonnell.bsky.social · 24/10/2025

Our new preprint outlining how to make 1000-plex mass tags!

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Reposted by @kmcdonnell.bsky.social

Jason Derks @jasonderks.bsky.social · 28/05/2025

We are excited to introduce ‘time’ as a new domain for proteomics multiplexing! It enables: -Label-free multiplexing -Combinatorial multiplexing with plexDIA Using combined 9-plexDIA and 3-timePlex we demonstrate 27-plex DIA 🚀

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Harrison Specht @harrisons.bsky.social · 28/05/2025

🧪 Transforming biomedical discovery needs proteomics that is specific and accurate, but also faster and cheaper @parallelsq.bsky.social is proud to introduce 9-plex PSMtags: a new mass tag that improves sequencing and increases throughput in sensitive proteomics 👇 www.biorxiv.org/content/10.1...

biorxiv.org

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kmcdonnell.bsky.social @kmcdonnell.bsky.social · 28/05/2025

Increasing throughput in mass spec proteomics requires new ways to model the increased complexity of the spectra. We are delighted to share JMod, our new open source software developed at @parallelsq.bsky.social , which enables new multiplexing approaches. 1/7 www.biorxiv.org/content/10.1...

biorxiv.org

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