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Kewin Siah

@kewinsiah.bsky.social
469 followers 759 following 63 posts

Gastroenterologist specializing in DGBIs. Adjunct A/Prof at the National University of Singapore. President of IBS Support Group Singapore. Passionate about IBS, constipation, gastroparesis, and gut health.

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Kewin Siah @kewinsiah.bsky.social · 05/07/2025
🌏 Join us in Jakarta for ANMA 2025 🇮🇩 — the premier neurogastroenterology event in Asia! 📆 4–6 September 2025 🏨 Ritz Carlton Mega Kuningan Hotel 🤝 In conjunction with IDDW 2025 Let’s advance #DGBI care together! 🔗 [iddwanma2025.com] #ANMA2025 #IDDW2025 #Neurogastroenterology #GIcare #Jakarta
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Kewin Siah @kewinsiah.bsky.social · 20/04/2025
The Korean🇰🇷 #IBS consensus is comprehensive, pragmatic, and harmonizes Western evidence with regional practice constraints, drug availability, and increasing psychosocial attention. www.jnmjournal.org/journal/view... #GIsky #DGNIsky
jnmjournal.org
2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome
Yonghoon Choi, Young Hoon Youn, Seung Joo Kang, Jeong Eun Shin, Young Sin Cho, Yoon Suk Jung, Seung Yong Shin, Cheal Wung Huh, Yoo Jin Lee, Hoon Sup Koo, Kwangwoo Nam, Hong Sub Lee, Dong Hyun Kim, Ye ...
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Kewin Siah @kewinsiah.bsky.social · 18/04/2025
We’ve put this sticker up in our hospital loo for #WorldIBSDay—proud to partner with NUHS+ to shine a light on IBS‑C. 👉 nuhsplus.edu.sg/article/back... #GISky #DGBISky
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Kewin Siah @kewinsiah.bsky.social · 01/04/2025
🆕 2025 USMSTF Bowel Prep Recommendations: ✅ Split-dose still #1 ✅ 2L preps now preferred 💧 ✅ Same-day OK for PM scopes (not AM) ✅ Low-residue > clear liquid diet ❗ Aim for >90% adequate prep 🤔 Simethicone? Possibly helpful. 🔓 Full text: www.giejournal.org/article/S001... #GIsky #MEdedsky
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Kewin Siah @kewinsiah.bsky.social · 22/03/2025
🧠💻 The AGA 2025 Guideline on CADe-assisted colonoscopy makes no recommendation—due to very low certainty in reducing #CRC incidence or mortality. ✅ ADR improve ⚠️ But more low-risk polyp detection → increased surveillance, cost & patient burden. #GiSky #GutSky www.gastrojournal.org/article/S001...
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Kewin Siah @kewinsiah.bsky.social · 15/03/2025
Vibrating Capsule shows promise in treating Chronic Constipation! Low adverse events (2.9% bloating, 2.9% abdominal pain) and high patient satisfaction (83% convenient, 71% satisfied). Read more: (link unavailable) #GISky #MedSky #DGBI 👉https://pubmed.ncbi.nlm.nih.gov/40059867/
pubmed.ncbi.nlm.nih.gov
The Vibrating Capsule: Safety and Tolerability in Patients With Chronic Idiopathic Constipation - PubMed
The Vibrating Capsule, a first in class treatment for CIC was found to be safe and well tolerated by patients in clinical trials. No patient discontinued treatment due to adverse events.
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Kewin Siah @kewinsiah.bsky.social · 13/03/2025
📚 New Research: Linaclotide outperforms Lactulose for treating Functional Dyspepsia + IBS-C overlap. 🌟 ✅ 87.2% of patients on Linaclotide reported symptom relief vs just 54.2% on Lactulose 📈 Bloating, abdominal discomfort, stool frequency 🔬 pubmed.ncbi.nlm.nih.gov/40079184/ #GutSky #IBSSky #DGBI
pubmed.ncbi.nlm.nih.gov
Efficacy of Linaclotide in Functional Dyspepsia and Constipation-Predominant Irritable Bowel Syndrome Overlap: A Randomized Trial - PubMed
ClinicalTrials.gov: NCT05134584.
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Kewin Siah @kewinsiah.bsky.social · 10/03/2025
"Constipation is a common GI symptom in pure autonomic failure, affecting nearly half of patients. It often shows up alongside other autonomic issues, highlighting the complexity of managing this condition. 🧠🚽 #NeurologySky #GutSky #ANSSky #https://pubmed.ncbi.nlm.nih.gov/40053259/
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Kewin Siah @kewinsiah.bsky.social · 04/03/2025
🚨 What raises your risk of #IBS? A new umbrella review of 69 systematic reviews highlights key factors: female gender, anxiety, depression & gastroenteritis. How can we improve prevention? #GutHealth #DGBISky #GISky
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Kewin Siah @kewinsiah.bsky.social · 04/03/2025
🚀 A breakthrough in motility testing! The #AtmoCapsule emerges as a solid alternative to the discontinued #SmartPill, showing strong correlation for gastric emptying & colonic transit times. A new era for GI transit assessment? #DrGutBrainExplains #GISky #DGBISky 🔓 www.cghjournal.org/article/S154...
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Kewin Siah @kewinsiah.bsky.social · 22/02/2025
🔥New study: Psychological stress can break oral tolerance to food, triggering IgE-mediated mast cell activation & gut pain hypersensitivity—offering insights into stress-induced IBS. #GISky #GutSky #DGBI #MedSky 📃https://els-jbs-prod-cdn.jbs.elsevierhealth.com/article/S0016-5085(25)00371-3/fulltext
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Kewin Siah @kewinsiah.bsky.social · 20/02/2025
Kudos to @AndySamberg & @BowenYang for tackling anxiety & #IBS in their #SNL song! Using comedy to break down stigma & spark conversations. Authentic representation matters! #MentalHealthMatters #GutHealthMatters #GITwitter 👉https://youtu.be/k94SUJ8UMKk?si=1QZhXfJO-L5RgDy_
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Kewin Siah @kewinsiah.bsky.social · 20/02/2025
First meeting of the APAGE Emerging Leader Committee DGBI Special Interest Group! Discussing initiatives for 2025 and beyond. Stay tuned for updates! #GiSky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 15/02/2025
Can't wait to reconnect with old friends at #DDW2025! 📷 So many events, so little time! See you all in 77 days and 4 hours! 📷📷 #BeGutsy #gicommunity #ddw2025 #DGBI #GISky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 10/02/2025
New study shows an IgG-based elimination diet improved #IBS symptoms in 59.6% of patients vs 42.1% on a sham diet (n=223). Interesting, but subgroup analysis suggests it may work better for IBS-C and IBS-M than IBS-D. #GISky #GutSky #DGBI pubmed.ncbi.nlm.nih.gov/39894284/
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Kewin Siah @kewinsiah.bsky.social · 08/02/2025
Advanced #Parkinson’s led to severe colonic dysmotility, fecal impaction, & kidney issues in a 77-yr-old. Treated with rectal tube + meds, but no cure for alpha-synuclein damage. 🚨 Early recognition key! #stoolcankill 🧠💩 #GISky #GutSky #constipation #DGBI #FGID pubmed.ncbi.nlm.nih.gov/39917098/
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Kewin Siah @kewinsiah.bsky.social · 08/02/2025
Are you thinking of signing up for #BlueSky? ▶️Use Sky follower bridge extension to follow people on bluesky that you follow on twitter! I www.sky-follower-bridge.dev/get-started.... ▶️Follow me! @kewinsiah.bsky.social Check out the #BlueSky's #DGBI Starter Pack also! 🌟➡️https://go.bsky.app/5PZzEvd
sky-follower-bridge.dev
Sky Follower Bridge
Instantly find and follow the same users from your 𝕏 followers on Bluesky
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Kewin Siah @kewinsiah.bsky.social · 07/02/2025
#Stoolcankill: Rare case of ileal fecaloma causing small bowel obstruction in a 60yo 🧓with chronic #constipation. Surgical intervention successfully resolved the obstruction. Highlights importance of considering fecaloma in SBO differentials. #GiSky #Gutsky #DGBI pubmed.ncbi.nlm.nih.gov/39905511/
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Reposted by Kewin Siah
Altmetric @altmetric.com · 18/11/2024
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
docs.bsky.app
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
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Reposted by Kewin Siah
Motilent @motilent.bsky.social · 19/11/2024
Gastroparesis: the chronic feeling of bloating, nausea & upper GI discomfort. With #GLP1 helping to boost the prevalence to 1-2% of the population, is it finally getting the attention it deserves? 🧵⬇️ #gisky #gastrosky #gastroparesis #IBD
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Kewin Siah @kewinsiah.bsky.social · 04/02/2025
Digital eHealth vs onsite 2-day IBS education: Digital program significantly ⬇️ symptom severity in 41% of pts & improved QoL, anxiety, depression. Both interventions scored high on client satisfaction. eHealth is a viable, for IBS self-management. #GutSky #GISky humanfactors.jmir.org/2025/1/e43618
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Kewin Siah @kewinsiah.bsky.social · 04/02/2025
#Gastroparesis Dx requires Sx like nausea/vomiting; asymptomatic cases excluded. N&V are key; bloating, pain less linked to severity. Overlaps with #FDyspepsia, but distinct patterns. QoL, mental health impacted. Weight loss not always present. #GutSky #GISky www.thelancet.com/journals/lan...
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Kewin Siah @kewinsiah.bsky.social · 01/02/2025
🚨 New @AmerGastroAssn update! 🚨 Screening & surveillance are key for #gastric cancer prevention in high-risk U.S. groups. Endoscopy + H. pylori eradication = crucial steps. Personalized risk-based approach needed. 🔗 doi.org/10.1053/j.ga... #GISky #medsky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 31/01/2025
A Japanese multicenter study found that comorbid #constipation was linked to a 90%⬆️mortality risk in #HeartFailure pts (P < 0.001) Among 715 patients, those with constipation had worse 2-year survival and higher cardiovascular mortality. #GISky #CardioSky #HeartSky pubmed.ncbi.nlm.nih.gov/39877026/
pubmed.ncbi.nlm.nih.gov
Impact of comorbid constipation on the survival of patients with heart failure: a multicenter, prospective cohort study conducted in Japan - PubMed
Constipation can negatively affect the survival of patients with heart failure. Although the causal link between constipation and decreased survival remains unclear, identifying comorbid constipation ...
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Kewin Siah @kewinsiah.bsky.social · 31/01/2025
🔍 Overtesting in IBS? A study of 26,732 IBS patients found that 85.3% of advanced serologic tests were ordered by GIs, yet only 12.5% followed guidelines, with a mere 2.1% positive rate. 💰 $39K wasted on unnecessary tests. Stick to Rome IV criteria! #GISky #GutSky pubmed.ncbi.nlm.nih.gov/39853154/
pubmed.ncbi.nlm.nih.gov
Specialty laboratory testing for chronic abdominal pain in irritable bowel syndrome - PubMed
The findings emphasize the effectiveness and importance of adhering to Rome IV criteria, as advanced testing often fails to improve diagnostic accuracy and increases unnecessary healthcare costs.
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Kewin Siah @kewinsiah.bsky.social · 28/01/2025
🌟 Recognizing #DGBI in patients with organic GI disease remission prevents overtreatment with risky drugs and ensures targeted care. Let’s focus on better outcomes! 👉 bit.ly/3Ee3iwv #GISky #MedSky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 27/01/2025
Excited share that our @romefoundation.bsky.social Working Team's manuscript 📄 on Overlap in Disorders of Gut-Brain Interaction #DGBI is now published in @natrevgastrohep.bsky.social! Grateful for this amazing journey with global experts. Read here: nature.com/articles/s41... #DGBI #GISky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 26/01/2025
New meta-analysis highlights acupuncture's potential for IBS-D patients—relieving symptoms, anxiety, and depression while boosting response rates. Promising steps forward for the gut-brain connection! 🌱🧠 #IBS #GutHealth #MentalHealth dx.doi.org/10.1097/MD.0... #GISky #GutSky #Medsky #DGBI #FGID
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Kewin Siah @kewinsiah.bsky.social · 26/01/2025
Heartburn is a key driver of healthcare utilization in GERD, yet insurance restrictions often shape management. Emerging #PCABs could reduce costs, improve QALYs, and align drug pricing ($8.57/pill) with clinical and economic value.#GERD #PCAB #DGBI www.cghjournal.org/article/S154...
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
I’ve been on Bluesky for a bit and felt we needed a space to bring the DGBI community together. So, I created the #DGBI Starter Pack! A place to connect, share ideas, and grow as a network. Join in and let’s make gut health the focus! #GISky #GutSKy #IBS 🌟➡️https://go.bsky.app/5PZzEvd
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
I've been on Bluesky for a while now, waiting for a starter pack to bring the #DGBI community together. Since none existed, I decided to create one myself! The DGBI Starter Pack is here to help us connect, share, and grow together. Join us and make gut health a priority! 🌐🌱 #GISky #GutSky #IBS #FGID
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
"How does colonoscopy impact gut microbiota? 🦠 New insights on changes, mechanisms, and probiotics for recovery in Clinical Endoscopy (2025). Highly recommended 🤓 ! 📖 doi.org/10.5946/ce.2... #GutSky #GISky #Microbiota
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
The brain and gut are closely connected through the brain-gut axis. 🧠💩 Anxiety can influence gut motility, while constipation can exacerbate psychological distress. Managing both is vital for overall well-being. 🌱 #GutHealth #MentalHealth bmcgastroenterol.biomedcentral.com/articles/10....
bmcgastroenterol.biomedcentral.com
Association of anxiety status and anxiety duration with constipation in adult Americans: a cross-sectional study using data from the NHANES 2007–2010 - BMC Gastroenterology
Background Constipated patients may exhibit anxious behaviors, but the relationship between the two remains unclear. This population-based study aims to investigate the relationships of anxiety status...
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Reposted by Kewin Siah
Johannah Ruddy @johannahruddy.bsky.social · 24/01/2025
A recent study found a complex, bidirectional relationship between marital quality and #DGBI symptoms in married Malay women. These findings underscore the importance of considering psychosocial factors when treating women with DGBIs.
A recent study found a complex, bidirectional relationship between marital quality and #DGBI symptoms in married Malay women. These findings underscore the importance of considering psychosocial factors when treating women with DGBIs.
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Reposted by Kewin Siah
Dr van Tilburg @drvantilburg.bsky.social · 24/01/2025
Children with #DGBI (e.g., Irritable Bowel, Constipation) face a higher risk of experiencing adverse childhood events ( #ACE ). Anxiety could be the missing link. 🧠 #MentalHealth #Pediatrics pubmed.ncbi.nlm.nih.gov/39584227/
pubmed.ncbi.nlm.nih.gov
The relationship between adverse childhood experiences and disorders of the gut-brain interaction - PubMed
Among patients receiving pediatric GI specialty care, higher ACE scores were associated with a higher likelihood of a DGBI diagnosis. Anxiety largely mediates this relationship, suggesting potential a...
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Reposted by Kewin Siah
Eric Topol @erictopol.bsky.social · 24/01/2025
Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions." www.nature.com/articles/d41...
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
Brilliant work by Christopher J. Black and Alexander on #IBS! 🌟 Comprehensive insights into diagnosis, dietary approaches, pharmacology, and gut-brain therapies. A must-read for anyone in #GIHealth #GutSky #GISky #DGBI pubmed.ncbi.nlm.nih.gov/39835671/
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Kewin Siah @kewinsiah.bsky.social · 24/01/2025
Autoimmune Pancreatitis: 🌟 From its classification into types 1 & 2 to cutting-edge treatments like glucocorticoids & B-cell depletion therapies, new insights redefine AIP care. Dive into this UEG review . 🔗 doi.org/10.1002/ueg2... #GIHealth #AutoimmunePancreatitis #GISky #GutSky
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Kewin Siah @kewinsiah.bsky.social · 22/01/2025
Constipation & fecal incontinence in neurological diseases go beyond the gut—they deeply impact mental health. Anxiety, distress, & ⬇️ QoL highlight the need for holistic care. It's time to prioritize psychological support in bowel management. 🧠 #GISKY #DGBI www.cochranelibrary.com/cdsr/doi/10....
cochranelibrary.com
Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central neurological diseases - Todd, CL - 2024 | Cochrane Library
Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.
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Kewin Siah @kewinsiah.bsky.social · 22/01/2025
#GLP-1 receptor agonists are transforming diabetes and obesity care but come with significant GI risks, including GERD, nausea, abdo pain, diarrhoea, and gastroparesis. Personalized care is key as we navigate these complexities. Read more: doi.org/10.1038/s415... #Gastrosky #GIsky #DGBI #ozempic
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Kewin Siah @kewinsiah.bsky.social · 18/01/2025
Is Lubiprostone still available in your country? 🤔 Lubiprostone shows efficacy in managing chronic idiopathic constipation, IBS-C, and opioid-induced constipation. This meta-analysis highlights improved bowel movements & quality of life. #Gutsky #GIsky #Gastrosky #DGBI doi.org/10.1002/jgh3...
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Reposted by Kewin Siah
Motilent @motilent.bsky.social · 20/11/2024
🤔Are all strictures created equal #gisky / #gastrosky? What's driving the obstruction? Fibrosis, inflammation, muscular hypertrophy or a combination? 🧵⬇️ #medsky
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Kewin Siah @kewinsiah.bsky.social · 17/01/2025
#Constipation is more than a nuisance in hemodialysis pts—it’s a risk factor. A Korean study of 35,230 pts links constipation to a 15% higher risk of stroke, myocardial infarction, or death. It’s time to address this silent threat. #Gutsky #GIsky #DGBI #Nephrology 🔗 krcp-ksn.org/journal/view...
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Kewin Siah @kewinsiah.bsky.social · 17/01/2025
Exciting update from @AmerGastroAssn! New quality indicators for #IBS emphasize evidence-based diagnosis, dietary interventions, and #brain–gut therapies to enhance patient care. 🌟 #GutHealth #Gisky #gutsky #DGBIsky Dive in: doi.org/10.1053/j.ga...
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
🚨 Asked to do a task outside your role? 🤔 ✅ Clarify boundaries ✅ Assess competence & patient safety ✅ Seek support if overwhelmed ✅ Use it as a chance to grow if feasible Know when to step up or step back—balance is key! 🩺 #GIsky #Gutsky #DGBI #Medsky www.bmj.com/content/388/...
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
Looking at integrative health for GI disorders? 🌟 This review dives into complementary approaches like nutrition, #mindfulness, and #acupuncture within a whole-person care model. Exciting advancements in holistic care! 🔗 doi.org/10.21037/tgh... #Gisky #gutsky #IntegrativeHealth #DGBI
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
93% of fibromyalgia patients meet criteria for at least one DGBI, with IBS present in 64%. Higher fibromyalgia severity is linked to greater gut dysfunction, emphasizing the gut-brain connection. Explore the data: doi.org/10.1002/ejp.... 🌟 #Fibromyalgia #DGBI #GutBrain #GIsky #Gutsky
doi.org
Fibromyalgia severity and symptoms are associated with the disorders of gut–brain interaction
Introduction Fibromyalgia remains an idiopathic common disorder characterised by widespread pain with no universally accepted treatment. Irritable bowel syndrome is prevalent among women living with...
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
Disaccharidase deficiencies are common in adults with chronic gas, #bloating, and abdominal pain (42% prevalence). Routine evaluation enables targeted treatments like dietary changes or enzyme therapy. 🧪 #GutSky #GISky #DGBI 🔗 journals.lww.com/ctg/abstract...
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
Machine learning stratified 1,044 #hEDS/HSD patients into 3 clusters: 466 #IBS + foregut disorders, 180 IBS only, and 337 with no DGBI. The IBS + foregut group had the highest rates of anxiety (p<0.0001), PoTS (45.5%) & reduced QoL (p<0.0001). #DGBIsky #gutsky #GIsky doi.org/10.1111/nmo....
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Kewin Siah @kewinsiah.bsky.social · 13/01/2025
New in Scientific Reports: inadequate bowel preparation in Chinese outpatients: 6 key risk factors: male sex, diabetes, chronic constipation, colorectal surgery history, high-fiber diet, and >5-hour interval before colonoscopy. Suggestion for improvement. #GIsky #Gutsky doi.org/10.1038/s415...
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