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Johannah Ruddy

@johannahruddy.bsky.social
329 followers 602 following 317 posts

GI researcher, author, speaker, patient advocacy director, passionate about IBS and patient care, doctorate in rural health

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Johannah Ruddy @johannahruddy.bsky.social · 29/09/2026
OIC starts fast. A new study shows ~24% of patients meet OIC criteria within 3 days of starting weak opioids, yet fewer than 2% show a drop in bowel movement frequency. 🩺 Listening to early patient self-awareness & symptoms like straining by Day 3 catches OIC early.
OIC starts fast. A new study shows ~24% of patients meet OIC criteria within 3 days of starting weak opioids, yet fewer than 2% show a drop in bowel movement frequency. 🩺

Listening to early patient self-awareness & symptoms like straining by Day 3 catches OIC early.
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Johannah Ruddy @johannahruddy.bsky.social · 23/09/2026
It’s Sepsis Awareness Month. Living with a CVC brings constant infection anxiety, but many patients feel unsure how to advocate for themselves. 🩺 @KidneyPatients created a pocket guide giving families clear questions for their care team to catch risks early & prevent sepsis!
linkedin.com
#sepsisawarenessmonth #everypatientsafe | American Association of Kidney Patients
Dialysis patients with a central venous catheter (CVC) can take steps to help prevent infections. This #SepsisAwarenessMonth, check out AAKP’s Pocket Guide to Managing Infection Risks for practical tips to help protect your health and stay informed. https://lnkd.in/eAKEvPaq #EveryPatientSafe
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Johannah Ruddy @johannahruddy.bsky.social · 21/09/2026
Heading to NYC next week for the 2026 PM360 Trailblazer Awards! 🩺 Thrilled to represent @Ardelyx alongside an incredible team nominated for Small Biotech of the Year, Best CEO, Best Marketing Team, & Best Podcast. I'm so excited to see all of you. Please reach out if you'd like to meet up!
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Johannah Ruddy @johannahruddy.bsky.social · 19/09/2026
Because substance use disorders often manifest as GI or liver complications, GI clinics can serve as a vital front line. 💡 Loved this guide because it highlights how Motivational Interviewing builds trust, dismantles stigma, and turns routine visits into bridges to care.
news.gastro.org
Substance use disorders in gastroenterology and hepatology: A practical guide for the general gastroenterologist
American Gastroenterological Association's official newspaper
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Johannah Ruddy @johannahruddy.bsky.social · 19/09/2026
This CGHjournal study tracking 40,000+ IBD patients shows psychiatric risks rise 2–3 years before formal diagnosis and stay elevated for years. When the gut and brain are connected this early, we can't treat mental health as an afterthought. Caring for the whole person starts on day one. 💛
news.gastro.org
Psychiatric risks rise before IBD diagnosis
American Gastroenterological Association's official newspaper
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Johannah Ruddy @johannahruddy.bsky.social · 18/09/2026
For millions with DGBIs, finding treatment is a game of trial & error. Researchers just built a "digital twin" of the gut-brain axis to map vagus nerve signals and test bioelectronic therapies. We're moving closer to repairing root signal disruptions rather than just managing symptoms.
news-medical.net
Digital twin of the gut-brain axis aims to advance neurostimulation therapies
The gut and brain are in constant conversation, exchanging signals that regulate hunger and digestion, as well as the body's response to stress.
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Johannah Ruddy @johannahruddy.bsky.social · 03/09/2026
Endoscopic surveillance is important to keep tabs on as our patients age. 💡 A new @AGA_Gastro update highlights when to de-escalate care. After age 75, risks often outweigh benefits. De-escalating isn't about withholding treatment; it’s practicing high-value, patient-centered bedside care.
news.gastro.org
AGA update sets limits on endoscopic surveillance in older adults
American Gastroenterological Association's official newspaper
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Johannah Ruddy @johannahruddy.bsky.social · 02/09/2026
Having purpose doesn't make the hard days in healthcare easy, but it gives them context. It reminds me why we push for better clinical protocols, advocate for patients, and take time to truly listen. When you know your why, even the most exhausting work becomes part of something deeply beautiful.
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Johannah Ruddy @johannahruddy.bsky.social · 01/09/2026
The fed vs. state AI debate has come for healthcare. States want guidance but a national standard is only as good as its protections. We need guardrails to stop insurers from auto-denying care while still advancing safe clinical practice. AI must enhance clinical judgment, not replace human care!
gi.org
AI Anarchy: The Federal-State Showdown Over Regulating Artificial Intelligence - American College of Gastroenterology
ACG opposes the recent OMB proposal to have political appointees approve all NIH research grants
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Johannah Ruddy @johannahruddy.bsky.social · 27/08/2026
True patient-centered trial design happens when patient advisors help shape the protocol before it's locked. Early engagement catches unfeasible visit schedules, improves quality-of-life endpoints, and prevents costly changes later on. Patient voice need to be heard on day one!
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Johannah Ruddy @johannahruddy.bsky.social · 26/08/2026
Really appreciated Dr. Kumkum Patel's breakdown on what diversifying income in GI actually looks like in practice. I learned a lot, especially about building entrepreneurial ventures alongside clinical work. It’s a realistic look at how women in medicine can build their business. Check it out!
gi.org
The ACG Women in Gastroenterology Podcast - American College of Gastroenterology
The ACG Women in Gastroenterology Podcast brings attention to impactful issues for the female gastroenterologist during fellowship and beyond.
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Johannah Ruddy @johannahruddy.bsky.social · 25/08/2026
Trial metrics like NNT directly shape bedside care. A new @AmJGastro study shows modern FDA endpoints raise IBS NNTs by ~2 units. Standardizing this data helps clinicians set honest expectations with patients and navigate treatment trial-and-error with real transparency. This is good!
journals.lww.com
https://journals.lww.com/ajg/fulltext/10.14309/ajg.0000000000003968~a-systematic-review-of-efficacy-in-irritable-bowel-syndrome
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Johannah Ruddy @johannahruddy.bsky.social · 24/08/2026
Nearly 80% of Americans search social media for health info, yet uncredentialed voices dominate the space. 💡 A great new G&H guide provides a practical framework for GI clinicians to navigate HIPAA, FTC rules & compliance. Meeting patients online with evidence & integrity matters!
news.gastro.org
A framework for ethical and legal social media use among gastroenterologists
American Gastroenterological Association's official newspaper
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Johannah Ruddy @johannahruddy.bsky.social · 14/08/2026
Patient advocacy in drug development isn't soft science, it's good strategy for the FDA. Building Patient-Reported Outcomes (PROs) into protocols pre-Phase 2 avoids costly trial amendments and aligns directly with FDA guidance on quality-of-life endpoints. Early insights build better pipelines.
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Johannah Ruddy @johannahruddy.bsky.social · 13/08/2026
Really exciting developments happening in endobariatric care! Dr. Shelby Sullivan highlights how expanding access to EBMTs delivers durable, cost-effective care and helps destigmatize chronic disease management. Absolutely loved reading this one.
gastroenterologyandhepatology.net
Riding the Wave of Rapid Innovation in Endobariatric Care - Gastroenterology & Hepatology
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Johannah Ruddy @johannahruddy.bsky.social · 10/08/2026
26% of EoE patients also have joint hypermobility, yet non-GI symptoms rarely get brought up in GI visits. A new @JACInews study links dysautonomia to active EoE. When we look beyond the esophagus and ask about the whole picture, we validate real patient experiences and deliver better care!
eosnetwork.org
Dysautonomia and joint hypermobility as a subtype of EoE
In a 2026 study, researchers identified a new subtype of EoE, characterised by dysautonomia, POTs and joint hypermobility. Learn more about this subtype and how it affects quality of life.
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Johannah Ruddy @johannahruddy.bsky.social · 07/08/2026
Trauma-informed GI care isn't just about empathy, it’s neurobiology. 🧠 Research shows that psychological processing can positively alter central nervous system responses, mitigating the development of DGBIs. Never minimize that addressing trauma is a real biological intervention!
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Johannah Ruddy @johannahruddy.bsky.social · 04/08/2026
When a treatment offers high efficacy with less post-procedure pain, getting guidelines right is a big deal for patients. Excited for this new @AmJGastro study establishing the 1st expert consensus for spray cryotherapy (LNSC) in Barrett’s & Esophageal Cancer. Safer care in action!
journals.lww.com
https://journals.lww.com/ajg/fulltext/10.14309/ajg.0000000000003752~spray-cryotherapy-esophageal-consortium-consensus
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Johannah Ruddy @johannahruddy.bsky.social · 30/07/2026
Patient engagement shouldn't be measured only by ROI, but by the value it creates throughout development. Bringing patients into decision-making early can improve study feasibility, strengthen evidence, and lead to therapies that better reflect real-world needs.
pharmaphorum.com
Moving from patient centricity to patient partnership
The desire for patients to be active partners in research challenges how organisations approach patient engagement.
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Johannah Ruddy @johannahruddy.bsky.social · 28/07/2026
Sometimes the biggest opportunity to improve outcomes is using the tools we already have more consistently. Better CKD screening can identify patients earlier, enabling timely intervention and reminding us that implementation is a powerful form of innovation.
pharmacytimes.com
Pharmacists Can Catch Missed CKD With One Question | Pharmacy Times
Boston University researchers say flat chronic kidney disease (CKD) prevalence conceals a growing diabetes-linked burden, and pharmacists have a key role in closing screening gaps.
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Johannah Ruddy @johannahruddy.bsky.social · 27/07/2026
Nutrition is one of healthcare's most underutilized interventions. Evidence shows that programs making healthy food more accessible can improve blood pressure, A1c, and hospitalizations, reminding us that supporting healthy choices is just as important as recommending them.
ama-assn.org
Ditching the “SAD plate” to prevent and control chronic disease
The Standard American Diet—or SAD plate—contributes to high rates of chronic disease. Using the “food is medicine” approach can help your patients. 
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Johannah Ruddy @johannahruddy.bsky.social · 23/07/2026
Patient-centricity isn’t separate from innovation or business outcomes. Research suggests every $1 invested in patient insights can generate up to a $500 return by improving recruitment, accelerating timelines, and supporting stronger commercialization.
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Johannah Ruddy @johannahruddy.bsky.social · 22/07/2026
IBS has long been viewed through the gut–brain connection, but new research highlights another piece: metabolism. Findings from nearly 2.8M people suggest IBS may be driven by multiple pathways, bringing us closer to more personalized approaches based on each patient’s biology.
the-scientist.com
Fat Metabolism Plays an Unexpected Role in IBS | The Scientist
A global genetic study of 2.8 million people revealed that blood triglyceride levels and liver function help drive irritable bowel syndrome risk.
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Johannah Ruddy @johannahruddy.bsky.social · 20/07/2026
Patient-centricity shouldn't begin after approval. When medical affairs helps bring patient perspectives into development earlier, studies become more relevant, evidence becomes more meaningful, and therapies are better positioned for real-world success.
appliedclinicaltrialsonline.com
Bringing the Voice of Clinical Practice and Patients into Drug Development | Applied Clinical Trials Online
The evolving role of medical affairs in connecting patients, physicians, and evidence generation.
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Johannah Ruddy @johannahruddy.bsky.social · 16/07/2026
The promise of remote patient monitoring is the shift from reactive to proactive care. One program reduced hospitalizations by 59%, while another saved Medicare $1,302 per patient annually. www.fastcompany.com/91567643/how-re…
The promise of remote patient monitoring is the shift from reactive to proactive care. One program reduced hospitalizations by 59%, while another saved Medicare $1,302 per patient annually.

https://www.fastcompany.com/91567643/how-remote-patient-monitoring-advances-affordable-healthcare
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Johannah Ruddy @johannahruddy.bsky.social · 14/07/2026
Healthcare starts long before a diagnosis. Supporting food security, education, children's health, and community programs is also an investment in better health outcomes. Philanthropy has the power to strengthen the environments where well-being begins.
goodgoodgood.co
Taylor Swift and Travis Kelce's big wedding present: $26M donated to charity
The couple still has yet to confirm their nuptials, but it seems they’re in the mood to celebrate something big.
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Johannah Ruddy @johannahruddy.bsky.social · 13/07/2026
One of the biggest shifts in GI research is moving beyond "IBS causes anxiety" or "anxiety causes IBS." Studies like this suggest they're part of the same interconnected gut-brain system—a perspective that could lead to more personalized care.
medicalxpress.com
A species of gut bacteria could ease anxiety and diarrhea-predominant IBS
Irritable bowel syndrome (IBS) is a condition characterized by abdominal pain, bloating and changes in bowel movements, estimated to affect between 10% and 15% of people worldwide. Past studies suggest that in many cases this condition is accompanied by anxiety, an emotional state marked by worry, fear and/or overthinking about specific life events.
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Johannah Ruddy @johannahruddy.bsky.social · 09/07/2026
Healthcare is very effective at measuring activity—discharges completed, portal activations, bills sent, follow-ups scheduled. These are important operational indicators, but they do not answer whether the patient’s issue was actually resolved.
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Johannah Ruddy @johannahruddy.bsky.social · 09/07/2026
In IBD, symptoms like urgency and abdominal pain often become routine before patients seek care. Creating space for honest conversation is key because earlier, more open dialogue can directly impact diagnosis and outcomes.
hcplive.com
Open Communication Between Patients and Providers in IBD | HCPLive
Embarrassing gut issues deserve answers: testing can uncover IBS or Crohn’s, and early biologic treatment helps achieve remission.
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Johannah Ruddy @johannahruddy.bsky.social · 30/06/2026
On Gut Matters, I spoke with Mike Raab and Dr. Laura Williams about what patient centricity looks like in practice. And we kept coming back to this idea: it’s not what we say or intend, it’s what we choose when tradeoffs show up.
bloodstreammedia.com
Beyond the Bumper Sticker: What Patient Centricity Really Means — BloodStream Media
On this episode of Gut Matters, host Johannah Ruddy sits down with Ardelyx CEO Mike Raab and Chief Patient Officer Dr. Laura Williams to explore what patient centricity truly means in practice, not as a corporate buzzword, but as a guiding principle that shapes company culture, strategy, and decisio
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Johannah Ruddy @johannahruddy.bsky.social · 25/06/2026
We’re still learning just how deeply connected the brain and gut really are, and PTSD is one of the clearest examples of that link:
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Johannah Ruddy @johannahruddy.bsky.social · 24/06/2026
Even after Crohn’s symptoms improve, biology may not fully reset. A new study of >1M gut cells found persistent gene activity changes across 50+ cell types and a “molecular scar” in gut stem cells. It challenges how we define remission in IBD.
news-medical.net
Gut cell study discovers lasting molecular scars of Crohn's disease
A detailed cellular study of Crohn’s disease has mapped how gene activity changes across more than 50 cell types in the gut.
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Johannah Ruddy @johannahruddy.bsky.social · 19/06/2026
As AI becomes more embedded in healthcare, trust may depend less on perfect accuracy and more on transparency. Patients want to know how AI is being used, where human judgment fits in, and how decisions are made. Technology advances when trust advances with it.
ohio.edu
Transparency is vital for AI usage in health care, patient-provider relationship, OHIO researchers find
Ohio University Professors Gaurav Bansal and Vic Matta have found that addressing transparency concerns is the most critical way to foster trust in primary care providers and improve patient outcomes.
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Johannah Ruddy @johannahruddy.bsky.social · 17/06/2026
One of the biggest shifts in GI care has been recognizing that symptoms aren't just driven by what's happening in the gut. Biology, stress, environment, and lived experience all play a role. The future of gut-brain care is personalized medicine and understanding.
medicalxpress.com
How culture, stress, and social life may shape gut health
Abdominal pain before an important exam, nausea during intense stress, or sudden intestinal problems following difficult life experiences—many people regard such symptoms as a temporary bodily reaction. However, a growing body of evidence confirms that the relationship between the brain and the gut is far deeper. A publication co-authored by Professor Agata Mulak of Wroclaw Medical University indi
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Johannah Ruddy @johannahruddy.bsky.social · 16/06/2026
Proud to see our team support Youth Enrichment Services and Scientific Adventures for Girls through partnerships with Life Science Cares Boston and Bay Area. Investing in young people’s curiosity, confidence, and opportunities today helps shape the innovators and leaders of tomorrow.
Proud to see our team support Youth Enrichment Services and Scientific Adventures for Girls through partnerships with Life Science Cares Boston and Bay Area.

Investing in young people’s curiosity, confidence, and opportunities today helps shape the innovators and leaders of tomorrow.Proud to see our team support Youth Enrichment Services and Scientific Adventures for Girls through partnerships with Life Science Cares Boston and Bay Area.

Investing in young people’s curiosity, confidence, and opportunities today helps shape the innovators and leaders of tomorrow.
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Johannah Ruddy @johannahruddy.bsky.social · 12/06/2026
In many cases, a second opinion doesn’t change the recommendation; it changes understanding. Especially in GI care, where decisions involve trade-offs, clarity in the “why” behind a plan can be just as important as the plan itself.
theconversation.com
Should you get a second medical opinion? A surgeon explains why doing so can make you a more confident patient
Seeking a second opinion is a patient’s right. Knowing how empowering another perspective can be may make it less awkward to ask for one.
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Johannah Ruddy @johannahruddy.bsky.social · 11/06/2026
Revisiting this Pride Month episode on GI care in the LGBTQIA+ community. Access to affirming care shapes patient outcomes! www.bloodstreammedia.com/gut-matter…
Revisiting this Pride Month episode on GI care in the LGBTQIA+ community. Access to affirming care shapes patient outcomes!

https://www.bloodstreammedia.com/gut-matters-discoveries-and-innovations-episodes/embrace-the-rainbow-digestive-health-in-the-lgbtqia-community
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Johannah Ruddy @johannahruddy.bsky.social · 05/06/2026
The conversation around hormone replacement therapy for menopause has been shaped for years by concerns that the evidence doesn't actually support, at least not the way patients have heard them.
medscape.com
Don’t Let Fear Guide Your Approach to Menopause Care
Are we overestimating the harms of menopausal hormone therapy? The Curbsiders debunk common fears about hormone therapy and share practical prescribing pearls for primary care physicians.
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Johannah Ruddy @johannahruddy.bsky.social · 04/06/2026
Stress slowing digestion isn't new information. What's new is understanding exactly where in the gut it breaks down, and that restoring that pathway brought gut function back in preclinical models. A potential treatment target for IBS-C worth watching.
news.harvard.edu
How stress hormones disrupt the gut — Harvard Gazette
New study traces network of nerves that disrupt digestion, pointing to potential IBS treatment.
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Johannah Ruddy @johannahruddy.bsky.social · 03/06/2026
Endometriosis affects roughly 170 million women globally. On average, it takes 6.8 years to get a diagnosis. In the US, that number can stretch to 11 years. That's not a small gap; in fact, that's years of pain, disease progression, and in many cases, lost fertility.
ajmc.com
5 Conditions Endometriosis Is Commonly Mistaken For—and Why Getting It Right Matters | AJMC
Endometriosis is often mistaken for IBS, fibroids, UTIs, PID, and ovarian cysts, potentially delaying diagnosis, treatment, and fertility care for years.
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Johannah Ruddy @johannahruddy.bsky.social · 02/06/2026
Most people think celiac looks one way. In kids, it often doesn't. Subtle symptoms get missed, and the longer it goes undiagnosed, the higher the stakes. If something hasn't been explained, it's worth asking your doctor about celiac.
walb.com
Tiny Guts, Tough Fight: Celiac Disease in Children
Celiac disease is something that most people may not know they have.
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Johannah Ruddy @johannahruddy.bsky.social · 01/06/2026
Pancreatic cancer is the 11th most common cancer in the U.S. right now. But based on current trends, it's projected to become the 2nd leading cause of cancer-related death by 2030. That gap between where it ranks and where it's heading is worth paying attention to.
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Johannah Ruddy @johannahruddy.bsky.social · 27/05/2026
In this study, insomnia affected over a third of IBS patients, but wasn’t driven mainly by GI symptoms; it was more closely tied to psychological distress and comorbidities. A great reminder that similar symptoms can mask very different lived experiences.
medscape.com
Insomnia Tied to Greater Symptom Burden in IBS
Insomnia affects a substantial subset of patients with irritable bowel syndrome and is linked to a higher burden of somatic and psychological symptoms and impaired quality of life.
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Johannah Ruddy @johannahruddy.bsky.social · 22/05/2026
In chronic GI conditions, clinical success and lived experience are not always aligned. This celiac disease research reinforces that managing symptoms is only part of care—the daily burden of food, vigilance, and social navigation still deeply affects quality of life.
celiac.com
Why Life with Celiac Disease Hasn't Improved in 10 Years, According to New Study
A new decade-long study from Spain reveals that quality of life for adults with celiac disease has not significantly improved, highlighting ongoing challenges beyond a gluten-free diet.
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Johannah Ruddy @johannahruddy.bsky.social · 20/05/2026
Below, Dr. Laura Williams and two patients discuss life with chronic illness beyond the clinical lens, showing that care improves through trust: www.bloodstreammedia.com/gut-matter…
Below, Dr. Laura Williams and two patients discuss life with chronic illness beyond the clinical lens, showing that care improves through trust:

https://www.bloodstreammedia.com/gut-matters-discoveries-and-innovations-episodes/finding-your-care-partner-patient-stories-that-break-the-stigma
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Johannah Ruddy @johannahruddy.bsky.social · 19/05/2026
Love this chart-- it's a great reminder that whether disabilities are visible or not, they impact the patient experience. Some helpful points to keep in mind below!
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Johannah Ruddy @johannahruddy.bsky.social · 18/05/2026
This research highlights an important point: patients don’t necessarily want “AI or human” interpretation. What they really want is communication that feels clear, timely, and appropriate for the moment. In healthcare, flexibility may sometimes matter more than standardization.
digitaljournal.com
Overcoming the healthcare language barrier with AI
The AI approach is grounded in a modified technology acceptance model (TAM) that assesses patient perspectives.
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Johannah Ruddy @johannahruddy.bsky.social · 14/05/2026
IBS is often framed as diet-related, but it’s far more complex. Food triggers vary widely, and without guidance, over-restriction can cause new issues. This study reinforces that structure and support—paired with digital tools—are key to effective, personalized IBS care.
medicalxpress.com
A new online tool for tackling irritable bowel syndrome
Irritable bowel syndrome (IBS) is the most common gastrointestinal condition worldwide, affecting about 1 in 10 people, primarily women. Those who have it suffer abdominal pains and also often develop mental-health issues such as anxiety and depression, significantly impacting their quality of life. IBS cannot be cured and no single treatment is universally effective, so what's left is to manage t
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Johannah Ruddy @johannahruddy.bsky.social · 13/05/2026
Landmarks lit purple for #WorldIBSDay2026 were a powerful reminder of growing awareness for IBS-C. It's continued visibility like this that helps improve understanding, earlier diagnosis, and more empathetic conversations in care. Grateful for the Ardelyx team for making this happen!
Landmarks lit purple for #WorldIBSDay2026 were a powerful reminder of growing awareness for IBS-C. It's continued visibility like this that helps improve understanding, earlier diagnosis, and more empathetic conversations in care. 

Grateful for the Ardelyx team for making this happen!Landmarks lit purple for #WorldIBSDay2026 were a powerful reminder of growing awareness for IBS-C. It's continued visibility like this that helps improve understanding, earlier diagnosis, and more empathetic conversations in care. 

Grateful for the Ardelyx team for making this happen!Landmarks lit purple for #WorldIBSDay2026 were a powerful reminder of growing awareness for IBS-C. It's continued visibility like this that helps improve understanding, earlier diagnosis, and more empathetic conversations in care. 

Grateful for the Ardelyx team for making this happen!
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Johannah Ruddy @johannahruddy.bsky.social · 12/05/2026
This research reinforces that overeating is both behavioral and physiological. When gut-brain communication is disrupted, hunger and fullness signals change. That shifts the conversation from willpower to biology, and potentially to better treatment models.
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