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Kevin Blake PhD

@kevinsblake.bsky.social
36 followers 37 following 60 posts

Scientist + Writer.

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Kevin Blake PhD @kevinsblake.bsky.social · 06/08/2026
Can we treat infectious disease *without* killing microbes? 🦠💊🧪 Scientists are investigating how to end the War on Bacteria with more "diplomatic" approaches. They are: 1. Disarming virulence 2. Building tolerance 3. Promoting colonization resistance Read more about it here 👉
kevinsblake.substack.com
Pathogens to Pacifists
Curing infections without killing bacteria.
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Saloni @scientificdiscovery.dev · 28/05/2026
We take it for granted today that DNA is the genetic code of life, but until the 1940s most scientists thought genes were made of protein! In a new piece, @kevinsblake.bsky.social tells the story of how scientists discovered that DNA is the code of life.
worksinprogress.co
How bacteria solved the mystery of inheritance - Works in Progress Magazine
In the 1940s, scientists made a discovery now fundamental to biology: genes are encoded in DNA. The story involves bacteria, dead mice, and a kitchen cream separator.
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Kevin Blake PhD @kevinsblake.bsky.social · 28/05/2026
The foundational discovery of modern genetics -- that genes are made of DNA -- came from an organism many doubted even had genes: bacteria 🧬🧫 Read more in my piece @worksinprogress.bsky.social worksinprogress.co/issue/how-ba...
worksinprogress.co
How bacteria solved the mystery of inheritance - Works in Progress Magazine
In the 1940s, scientists made a discovery now fundamental to biology: genes are encoded in DNA. The story involves bacteria, dead mice, and a kitchen cream separator.
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Kevin Blake PhD @kevinsblake.bsky.social · 05/05/2026
Did you know: Mark Twain wrote a book about a microbiologist who is accidentally transformed into a "cholera germ"? 🦠🧪 Though written over 100 years before the term “microbiome” was coined, its descriptions of the human body from the microbe’s-eye view could be home in any modern text.
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Pablo Ivan Nikel @pabnik.bsky.social · 27/01/2026
Should an iconic #bacterial #chassis be renamed without community consensus? Our @mbio.bsky.social #article vindicates the established identity of #Pseudomonas putida KT2440 & argues for continuity, community practice & common sense in naming · @vdlorenzo.bsky.social journals.asm.org/doi/10.1128/...
journals.asm.org
The disputed identity of Pseudomonas putida KT2440: when taxonomists rename your favorite microbe | mBio
Names matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad...
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Kevin Blake PhD @kevinsblake.bsky.social · 26/01/2026
Tech CEOs claim there's been a "Cambrian Explosion in AI." This is usually just marketing-speak for "rapid, transformative growth." But assuming the metaphor is accurate, maybe we can find clues for what's next--is there a bubble?--in what followed the ACTUAL Cambrian explosion?
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STCmicrobeblog @stcmicrobeblog.bsky.social · 26/01/2026
These Are the Times by Roberto — Microbiologists continue to advance the frontiers of knowledge.
smallthingsconsidered.blog
These Are the Times
by Roberto — Microbiologists continue to advance the frontiers of knowledge.
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CMI Communications @cmicomms.bsky.social · 01/12/2025
We are very excited to have launched this new collaboration with @gardp.bsky.social! 🚀 This first jointly published commentary on #AMR by @kevinsblake.bsky.social & Gautam Dantas can also be read on our journal page: www.cmi-comms.org/article/S295... #IDSky #clinmicro
cmi-comms.org
Ecological strategies to end the war on resistance
Military metaphors are pervasive in the language of antibiotics and resistance [1]. Bacterial pathogens are foreign invaders with whom we are at war. To fight them, we deploy antibiotic chemical weapo...
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Global Antibiotic R&D Partnership (GARDP) @gardp.bsky.social · 30/11/2025
📝 A new Antimicrobial Viewpoint by Kevin Blake and Gautam Dantas examines public framing of AMR and proposes alternatives to the war metaphor. The piece is jointly published on REVIVE and CMI Communications. 🔗https://tinyurl.pulse.ly/jjtqv3dn37 Got a topic idea? Write to revive@gardp.org
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Kevin Blake PhD @kevinsblake.bsky.social · 24/11/2025
Every biologist knows the story of Fleming's chance discovery of penicillin. But is it true? Here, with @asimovpress.bsky.social, I write about inconsistencies in the canonical story, and explore a few alternative theories about what really happened in that St. Mary's lab in the summer of 1928.
press.asimov.com
The Penicillin Myth
Competing theories seek to explain inconsistencies surrounding Alexander Fleming’s famed discovery.
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Kevin Blake PhD @kevinsblake.bsky.social · 05/11/2025
Darwin thought evolution required thousands of years, and was therefore out of reach from human experimentation. But in one of the few forms of life he didn’t study -- microorganisms -- evolution can happen in mere months or weeks 🦠🧫
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Kevin Blake PhD @kevinsblake.bsky.social · 27/10/2025
The "war on antibiotic resistance" won't end with brute force alone 💊🧫 Instead, eco-evo strategies take a more diplomatic approach. These seek to foster co-existence with microbes, rather than kill them. We metaphorize these as: disarmament, non-proliferation, and soft power.
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Kevin Blake PhD @kevinsblake.bsky.social · 29/09/2025
Antibiotic resistance is portrayed as the enemy of modern medicine. But nothing in biology is inherently evil. Could it be useful, even “good”? 💊🔬 I wrote about using resistance enzymes to protect the gut microbiome from antibiotics and prevent secondary infections. 🧫🦠
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Kevin Blake PhD @kevinsblake.bsky.social · 29/05/2025
Are chromosomes merely a laundry list of genes? I wrote for @stcmicrobeblog.bsky.social about new research which finds that natural selection has organized nearly 2/3s of bacterial genes into specific positions on the chromosome 🧪 🧫 🧬
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Kevin Blake PhD @kevinsblake.bsky.social · 22/05/2025
Where does antibiotic resistance come from? 💊🧫 I wrote for @asimovpress.bsky.social about proactive approaches for fighting resistance that shift focus from studying it in clinical pathogens to studying it at the source: soil-dwelling bacteria.
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Kevin Blake PhD @kevinsblake.bsky.social · 07/05/2025
Mark Twain wrote, “If the Eiffel tower were now representing the world’s age, the skin of paint on the pinnacle-knob at its summit would represent man’s share of that age.” 🧪🌐
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Kevin Blake PhD @kevinsblake.bsky.social · 30/04/2025
Multichannel pipette, in LEGO 🧪🔬
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Kevin Blake PhD @kevinsblake.bsky.social · 13/04/2025
I wrote about the discovery of lariocidin, a new class of antibiotic from slow-growing soil bacteria.
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Kevin Blake PhD @kevinsblake.bsky.social · 03/04/2025
{NatParksPalettes} now has >10k downloads! 🧪🎨⛰️🏜️ Very cool to see this little side project (really, done to procrastinate thesis experiments) be used by so many people.
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Kevin Blake PhD @kevinsblake.bsky.social · 27/03/2025
LEGO’s DNA Helix Isn’t “Right” 🧪 #MicroSky kevinsblake.substack.com/p/legos-dna-...
kevinsblake.substack.com
LEGO's DNA Helix Isn't "Right"
The Evolution of STEM is a wonderful new set marred by an unfortunate scientific inaccuracy.
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Kevin Blake PhD @kevinsblake.bsky.social · 13/03/2025
Call me old fashioned, but I’d think the mission of the Environmental Protection Agency should be something like, “protecting the environment.”
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Kevin Blake PhD @kevinsblake.bsky.social · 23/02/2025
Excited to share the final paper of my PhD! We competed dozens of tetracycline-resistant strains in the context of different generations of tet drugs—in effect, reconstructing the history of tet resistance in a test tube.
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Katie Mack @astrokatie.com · 12/02/2025
I have work to do but I'm distracted by watching US scientific progress & leadership being irreversibly undermined because a few unelected malcontents are penalizing researchers for following legal requirements set out by congressional orders to augment basic research with benefits to society.
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Kevin Blake PhD @kevinsblake.bsky.social · 05/02/2025
The Medium Blog featured my essay on the 2024 Nobel Prize in Chemistry in their guide for academics writing on the platform, as "recommended reading." 🧪 blog.medium.com/three-academ...
blog.medium.com
Three Academic and Scholarly Experts Share Their Top Medium Tips
Plus, our Academics Hour video recording and full transcript
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Katie Mack @astrokatie.com · 28/01/2025
I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service. “Pausing” grants means people don’t eat.
washingtonpost.com
White House pauses all federal grants, sparking confusion
The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.
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Tyler Kent @tylervkent.bsky.social · 28/01/2025
University of Chicago is asking researchers to halt purchases, starting new experiments, and travel in light of the federal pause on grants
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Kevin Blake PhD @kevinsblake.bsky.social · 17/12/2024
Why it's the phrase "the only good Helicobacter pylori is a dead [one]" that should be eliminated, not the bacterium 🧪🦠🔬
medium.com
Penatekas and Pylori: The Extermination of a Stomach Pathogen
Why it’s the phrase “the only good Helicobacter pylori is a dead [one]” that should be eliminated, not the bacterium
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Kevin Blake PhD @kevinsblake.bsky.social · 26/11/2024
Probiotics are one of the most commonly consumed dietary supplements. But a growing body of mixed and mostly unconvincing scientific research shows many aren't doing anything at all. 🧪🦠🔬 Read my article on it here 👉 medium.com/the-quantast...
medium.com
Probiotics Don’t Help “Gut Health”
Probiotics manufacturers are full of, well, the same stuff that has their customers backed up
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Kevin Blake PhD @kevinsblake.bsky.social · 20/11/2024
Had a blast working with the Dantas Lab team to create this graphical abstract, now published in Cell Chem Biol. This was a tour de force of scientific work, including: 🧪 in vitro biochemistry 🧬 genetic engineering 🚦 gut transit dynamics 🐁 in vivo mouse models #scienceart #sciencecommunication
Front page of journal article, including an illustration of a mouse ingesting engineered yeast, which reduces tumor burden.
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Kevin Blake PhD @kevinsblake.bsky.social · 14/11/2024
Replace "Canva" with "BioRender" and this article becomes an excellent critique on the homogenization of scientific illustration. 🧪 medium.com/westenberg/t...
medium.com
The Canva-ification of everything
Scroll through any social feed for a few moments, and every image seems to blend together into a uniform aesthetic. It’s all pastel colors…
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Kevin Blake PhD @kevinsblake.bsky.social · 14/11/2024
Important reasons to use a professional scientific illustrator to make your figures, rather than BioRender: www.chemistryworld.com/news/thousan...
chemistryworld.com
Thousands of published studies may contain images with incorrect copyright licences
Questions raised over copyright licence that covers images created using scientific illustration service Biorender
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Kevin Blake PhD @kevinsblake.bsky.social · 03/09/2024
The 16S rRNA gene is the standard for differentiating between bacterial taxa by DNA sequencing. But what does it mean when one species' sole copy isn’t encoded on the chromosome, but a 9-kb plasmid? Read my story about this evolutionary oddball #MicroSky 🧪 medium.com/the-quantast...
medium.com
New species of plant bacteria reshapes our views on DNA organization
The unorthodox way one bacterium organizes its genome blurs the line between “essential” chromosomes and “accessory” plasmids.
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Kevin Blake PhD @kevinsblake.bsky.social · 12/08/2024
I wrote about a fatal case of MDR E. coli bacteremia which adapted to evade antibiotic treatment not once, but TWICE in ~1 month. With just a handful of mutations it became resistant to every antibiotic thrown at it.
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Kevin Blake PhD @kevinsblake.bsky.social · 23/05/2024
Such a disingenuous take. A paper without data / code is just a press release. Industry research shouldn't be held to a different standard (a lower standard) than academic research. www.nature.com/articles/d41...
nature.com
AlphaFold3 — why did Nature publish it without its code?
Criticism of our decision to publish AlphaFold3 raises important questions. We welcome readers’ views. Criticism of our decision to publish AlphaFold3 raises important questions. We welcome readers’ v...
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